“…The association between vaccination and graft rejection remains unclear. METHODS: We conducted a nested case-control study to evaluate the association between graft rejection and vaccination in corneal transplant recipients at Kaiser Permanente Southern California (KPSC) between January 2008 and August 2022. …”
Enlace del recurso
Enlace del recurso

“…In vitro time to kill assay was conducted according to ASTM protocol E2315-16. We reported CFU/ml at 3 different timepoints after exposure (30s, 60s, and 120s). …”
Enlace del recurso
Enlace del recurso

“…Adjusted 5-year survival between E. coli and ECFA was similar but significantly different between ECFA and ECFM BSI (29.2% vs. 21.7%; p=0.002). The analysis conducted on monomicrobial ECFM and VRE BSI indicated that their respective 5-year survival was similar (19.6% vs. 21.2%; p=0.753). …”
Enlace del recurso
Enlace del recurso

“…Subgroups analyses were conducted excluding clindamycin receipients with clinda-R isolates (subgroup 1) and also missing clindamycin AST(including D-test; subgroup 2). …”
Enlace del recurso
Enlace del recurso

“….: Advisor/Consultant|Moderna: Grant/Research Support|Novavax: Grant/Research Support|Pfizer: Advisor/Consultant|Seqirus: Advisor/Consultant Andrew Ustianowski, MD, PhD, Gilead: Honoraria|Gilead: Advisory Board|GSK: Honoraria|Janssen: Honoraria|Merck: Honoraria|Merck: Advisory Board|Sanofi: Honoraria|ViiV Healthcare/GSK: Advisory Board Stéphane De Wit, MD, AstraZeneca: Financial support for the conduct of this study Rohini Beavon, PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Jesse Thissen, MSc, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Seth Seegobin, PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Katie Streicher, PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Alexandre Kiazand, MD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Mark T. …”
Enlace del recurso
Enlace del recurso

“…The long-term prognosis and duration that patients harbor CRE is not well described. METHODS: We conducted a retrospective study of patients who had a culture that grew CRE within the VHA from 2016-2022. …”
Enlace del recurso
Enlace del recurso

“…We present our experience implementing in-house PCR testing on admission for screening of colonization with CA in an area of high prevalence. METHODS: Study conducted across the acute care and inpatient rehabilitation hospitals at a large integrated, university affiliated, public health system in Miami, Florida. …”
Enlace del recurso
Enlace del recurso

“…Our objective was to determine the incidence of PJI occurring ≤ 3 months (early), between > 3 and ≤ 12 months (delayed), and > 12 months (late) after primary TKA and to identify the organisms isolated from microbiologic cultures during each of these periods. METHODS: We conducted a retrospective study of patients in the Veterans Aging Cohort Study- National Cohort who underwent elective primary TKA in the VA between October 1, 1999 to September 30, 2019. …”
Enlace del recurso
Enlace del recurso

“…METHODS: This study was a Phase 3, randomized trial conducted in 8 countries (NCT03583333). Participants 18–90 years of age with HABP/VABP requiring intravenous (IV) antibiotic treatment were randomized 1:1 to receive either IV IMI/REL (500 mg IMI/250 mg REL) or PIP/TAZ (4000 mg/500 mg) administered every 6 h for 7–14 days. …”
Enlace del recurso
Enlace del recurso

“…METHODS: This prospective study was conducted at a single institution, where primary total joint arthroplasty and spine surgeries were performed. …”
Enlace del recurso
Enlace del recurso

“…METHODS: The Antibiotic Choice On ReNal outcomes (ACORN) study was a pragmatic randomized trial comparing piperacillin-tazobactam versus cefepime, conducted from November 2021 to October 2022; patient follow up concluded on November 4, 2022. …”
Enlace del recurso
Enlace del recurso

“…During Omicron variant sublineage predominance, September 4, 2022 – February 4, 2023, we conducted a multicenter prospective cohort study at 7 sites in the United States to assess vaccine effectiveness (VE) of bivalent COVID-19 vaccine boosters against laboratory-confirmed SARS-CoV-2 virus infection among children aged 5–17 years. …”
Enlace del recurso
Enlace del recurso

“…In support of these efforts, a systematic review of peer-reviewed literature was conducted to synthesize the evidence for risk factors for severe pediatric COVID-19. …”
Enlace del recurso
Enlace del recurso

“…In the HARMONIE trial conducted in the UK, France, and Germany (EudraCT 2022-000099-20), we evaluated the impact of nirsevimab on all cause LRTI hospitalisations, as well as RSV LRTI specifically. …”
Enlace del recurso
Enlace del recurso

“…MIC testing with ATM and relebactam (set at 4 mg/L) was conducted on isolates recovered from the model at 96 hrs. …”
Enlace del recurso
Enlace del recurso

“…METHODS: mDNA-seq analysis and subsequent xHYB targeted enrichment were conducted on two effluent samples per month from November 2018 to May 2021 from a sewer pipe connected to inpatient buildings at a university hospital with 1,200 beds and approximately 1,000 new admissions per month. …”
Enlace del recurso
Enlace del recurso

“…We explored the impact of outpatient C. difficile infection (oCDI) on patients’ healthcare-related quality of life (HRQoL). METHODS: We conducted this prospective study of adults aged ≥ 50 years within the Kaiser Permanente Southern California (KPSC) and Northwest (KPNW) healthcare delivery systems. …”
Enlace del recurso
Enlace del recurso

“…Structural analysis of identified substitutions was conducted on a prior cryo-electron microscopy-based model of the replication-transcription complex. …”
Enlace del recurso
Enlace del recurso

“…A noncompartmental analysis (NCA) was conducted, and a population PK model was developed to characterize adult PK and predict pediatric PK using allometric scaling. …”
Enlace del recurso
Enlace del recurso

“…Study staff sent weekly structured messages, and the message content was based on social support theory and encouraged unstructured peer-to-peer messaging and support. We conducted a single-arm pilot among 55 youth living with HIV aged 14-24 years recruited from a government health care facility serving a mixed-income area of Nairobi. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso