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571761por Siegler, Aaron J, Brock, James B, Hurt, Christopher B, Ahlschlager, Lauren, Dominguez, Karen, Kelley, Colleen F, Jenness, Samuel M, Wilde, Gretchen, Jameson, Samuel B, Bailey-Herring, Gina, Mena, Leandro A“…OBJECTIVE: The goal of this study is to assess the initiation and persistence in PrEP care for those randomized to a home-care intervention (electronic PrEP, ePrEP) relative to those assigned to the standard of care (control) condition. We will conduct additional assessments, including quantitative and qualitative analyses, to contextualize trial results and facilitate scale-up. …”
Publicado 2019
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571762por Arzika, Ahmed M., Maliki, Ramatou, Boubacar, Nameywa, Kane, Salissou, Cotter, Sun Y., Lebas, Elodie, Cook, Catherine, Bailey, Robin L., West, Sheila K., Rosenthal, Philip J., Porco, Travis C., Lietman, Thomas M., Keenan, Jeremy D.“…METHODS AND FINDINGS: In a cluster-randomized trial conducted from 23 November 2014 until 31 July 2017, 30 rural communities in Niger were randomized to 2 years of biannual mass distributions of either azithromycin (20 mg/kg oral suspension) or placebo to children aged 1 to 59 months. …”
Publicado 2019
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571763por Zakus, David, Moussa, Moise, Ezechiel, Mahamane, Yimbesalu, Joannes Paulus, Orkar, Patsy, Damecour, Caroline, Ghee, Annette E, MacFarlane, Matthew, Nganga, Grace“…METHODS: A two-arm cluster randomized trial was conducted from March to October 2016 in Dosso and Doutchi districts. …”
Publicado 2019
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571764The association between endometriosis and autoimmune diseases: a systematic review and meta-analysispor Shigesi, Nina, Kvaskoff, Marina, Kirtley, Shona, Feng, Qian, Fang, Hai, Knight, Julian C, Missmer, Stacey A, Rahmioglu, Nilufer, Zondervan, Krina T, Becker, Christian M“…OBJECTIVE AND RATIONALE: The aim of this study was to systematically review the literature on population-based studies investigating an association between endometriosis and autoimmune diseases and to conduct a meta-analysis of combinable results to investigate the extent and robustness of evidence. …”
Publicado 2019
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571765por Ma, Xiao-Hong, Wang, Shuang, Liu, Si-Yun, Chen, Kun, Wu, Zhi-Yuan, Li, Deng-Feng, Mi, Yong-Tao, Hu, Long-Bin, Chen, Zhong-Wei, Zhao, Xin-Ming“…The physical characterization including morphology (transmission electron microscopy), hydrodynamic size, and zeta potential (dynamic light scattering) was conducted for each of the probes. The antigen targeting and MRI ability for these four kinds of USPIO probes were studied in the GPC3-expressing murine hepatoma cell line Hepa1-6/GPC3. …”
Publicado 2019
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571766por Hollander, Karsten, Liebl, Dominik, Meining, Stephanie, Mattes, Klaus, Willwacher, Steffen, Zech, Astrid“…Before and after the intervention period, a 3-dimensional biomechanical analysis for barefoot and shod running was conducted on an instrumented treadmill. The passive control group did not receive any intervention but was also tested prior to and after 8 weeks. …”
Publicado 2019
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571767por Sáez de Asteasu, Mikel L., Martínez-Velilla, Nicolás, Zambom-Ferraresi, Fabricio, Casas-Herrero, Álvaro, Cadore, Eduardo L., Galbete, Arkaitz, Izquierdo, Mikel“…METHODS AND FINDINGS: We performed a secondary analysis of a single-blind randomized clinical trial (RCT) conducted from February 1, 2015, to August 30, 2017 in an Acute Care of the Elderly (ACE) unit in a tertiary public hospital in Navarre (Spain). 370 hospitalized patients (aged ≥75 years) were randomly allocated to an exercise intervention (n = 185) or a control (n = 185) group (usual care). …”
Publicado 2019
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571768por Xing, Yan, Lin, Nancy U., Maurer, Matthew A., Chen, Huiqin, Mahvash, Armeen, Sahin, Aysegul, Akcakanat, Argun, Li, Yisheng, Abramson, Vandana, Litton, Jennifer, Chavez-MacGregor, Mariana, Valero, Vicente, Piha-Paul, Sarina A., Hong, David, Do, Kim-Anh, Tarco, Emily, Riall, Dianna, Eterovic, Agda Karina, Wulf, Gerburg M., Cantley, Lewis C., Mills, Gordon B., Doyle, L. Austin, Winer, Eric, Hortobagyi, Gabriel N., Gonzalez-Angulo, Ana Maria, Meric-Bernstam, Funda“…BACKGROUND: The PI3K/AKT pathway is activated through PIK3CA or AKT1 mutations and PTEN loss in breast cancer. We conducted a phase II trial with an allosteric AKT inhibitor MK-2206 in patients with advanced breast cancer who had tumors with PIK3CA/AKT1 mutations and/or PTEN loss/mutation. …”
Publicado 2019
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571769“…METHODS: Average weekly alcohol consumption for men aged 16+ from the cross-sectional nationally representative Health Survey for England were used to 1) calculate annual population prevalence estimates for newly defined at-risk (> 14 to ≤21 units/week) male drinkers from 2011 to 2015 (N = 3487–3790), and 2) conduct logistic regression analyses for at-risk vs low risk male drinkers under the previous (> 21 vs ≤21 units/week) and new (> 14 vs ≤14 units/week) guidelines to assess characteristics associated with being at-risk drinkers under each guideline using 2015 data (N = 2982). …”
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571770por Starks, Tyrel J, Robles, Gabriel, Pawson, Mark, Jimenez, Ruben H, Gandhi, Monica, Parsons, Jeffrey T, Millar, Brett M“…Follow-up assessments are conducted at 3-, 6-, 9-, and 12-months postbaseline. …”
Publicado 2019
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571771por Sahiledengle, Biniyam“…METHODS: Data from the fourth round of the Ethiopian Health and Demographic Survey (EDHS) conducted in 2016 was used for this analysis. Descriptive statistics were computed. …”
Publicado 2019
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571772por Müller, Ivan, Smith, Danielle, Adams, Larissa, Aerts, Ann, Damons, Bruce P, Degen, Jan, Gall, Stefanie, Gani, Zaahira, Gerber, Markus, Gresse, Annelie, van Greunen, Darelle, Joubert, Nandi, Marais, Tracey, Nqweniso, Siphesihle, Probst-Hensch, Nicole, du Randt, Rosa, Seelig, Harald, Steinmann, Peter, Utzinger, Jürg, Wadhwani, Christina, Walter, Cheryl, Pühse, Uwe“…METHODS: A randomized controlled trial (RCT) will be conducted in 8 schools. Approximately 1000 grade 4 to grade 6 school children, aged 9 to 13 years, and approximately 60 teachers will be recruited during a baseline survey in early 2019. …”
Publicado 2019
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571773por Choi, Brian G, Dhawan, Tania, Metzger, Kelli, Marshall, Lorraine, Akbar, Awdah, Jain, Tushina, Young, Heather A, Katz, Richard J“…BACKGROUND: Randomized controlled trials conducted in Mediterranean countries have shown that the Mediterranean diet lowers adverse cardiovascular events. …”
Publicado 2019
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571774por Stewart, Rebekah J, Rossow, John, Eckel, Seth, Bidol, Sally, Ballew, Grant, Signs, Kimberly, Conover, Julie Thelen, Burns, Erin, Bresee, Joseph S, Fry, Alicia M, Olsen, Sonja J, Biggerstaff, Matthew“…METHODS: During an outbreak of H3N2v virus infections among agricultural fair attendees, we deployed a text-illness monitoring (TIM) system to conduct active illness surveillance among households of youth who exhibited swine at fairs. …”
Publicado 2019
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571775por Topalian, Suzanne L., Hodi, F. Stephen, Brahmer, Julie R., Gettinger, Scott N., Smith, David C., McDermott, David F., Powderly, John D., Sosman, Jeffrey A., Atkins, Michael B., Leming, Philip D., Spigel, David R., Antonia, Scott J., Drilon, Alexander, Wolchok, Jedd D., Carvajal, Richard D., McHenry, M. Brent, Hosein, Fareeda, Harbison, Christopher T., Grosso, Joseph F., Sznol, Mario“…DESIGN, SETTING, AND PARTICIPANTS: This was a secondary analysis of the phase 1 CA209-003 trial (with expansion cohorts), which was conducted at 13 US medical centers and included 270 patients with advanced melanoma, RCC, or NSCLC who received nivolumab and were enrolled between October 30, 2008, and December 28, 2011. …”
Publicado 2019
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571776“…Methods: A cross-sectional survey was conducted between August 2016 and December 2016. Self-administered questionnaires were completed, including a self-developed and structured socio-demographic questionnaire; a self-developed, validated, and self-reported Medication Literacy Scale for Hypertensive Patients (C-MLSHP) used for medication literacy measurement; and the Chinese Version of the Morisky Medication Adherence Scale-8 (C-MMAS-8), an eight-item validated, self-report scale for adherence measurement with a total score range of 0–8. …”
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571777por Ofori-Asenso, Richard, Chin, Ken L., Mazidi, Mohsen, Zomer, Ella, Ilomaki, Jenni, Zullo, Andrew R., Gasevic, Danijela, Ademi, Zanfina, Korhonen, Maarit J., LoGiudice, Dina, Bell, J. Simon, Liew, Danny“…DATA EXTRACTION AND SYNTHESIS: The methodological quality of included studies was assessed using The Joanna Briggs Institute’s Critical Appraisal Checklist for Prevalence and Incidence Studies. Meta-analysis was conducted using a random-effects (DerSimonian and Laird) model. …”
Publicado 2019
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571778por Nakimuli-Mpungu, Etheldreda, Musisi, Seggane, Wamala, Kizito, Okello, James, Ndyanabangi, Sheila, Birungi, Josephine, Nanfuka, Mastula, Etukoit, Michael, Mojtabai, Ramin, Nachega, Jean, Harari, Ofir, Mills, Edward“…Spearman rank order correlation analyses were conducted to determine associations between baseline depression symptoms and adherence to antiretroviral therapy (ART), viral load suppression, and other psychosocial variables. …”
Publicado 2019
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571779por Okala, Sandra G., Darboe, Momodou K., Sosseh, Fatou, Sonko, Bakary, Faye-Joof, Tisbeh, Prentice, Andrew M., Moore, Sophie E.“…METHODS AND FINDINGS: The Early Nutrition and Immune Development (ENID) trial was a randomised, partially blinded trial conducted between April 2010 and February 2015 in the rural West Kiang region of The Gambia, a resource-poor region affected by chronic undernutrition. …”
Publicado 2019
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571780“…METHODS: A single-center, prospective, randomized controlled study was conducted. The obese patients receiving hysteroscopy under intravenous anesthesia were randomly divided into three groups: Control group maintaining oxygen supply via face masks (100% oxygen, flow at 6 L/min), the WNJ Oxygen Group with WNJ (100% oxygen, flow: 6 L/min) and the WNJ SJOV Group with SJOV via WNJ [Jet ventilator working parameters:100% oxygen supply, driving pressure (DP) 0.1 MPa, respiratory rate; (RR): 15 bpm, I/E; ratio 1:1.5]. …”
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