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572661por Lauck, Sandra B., Baron, Suzanne J., Irish, William, Borregaard, Britt, Moore, Kimberly A., Gunnarsson, Candace L., Clancy, Seth, Wood, David A., Thourani, Vinod H., Webb, John G., Wijeysundera, Harindra C.“…METHODS AND RESULTS: We conducted a retrospective cohort study of patients treated in the United States between 2012 and 2019 using data from the Medicare Data Set Analytic File 100% Fee for Service database. …”
Publicado 2021
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572662por Zhang, Jie, Pan, Yueyin, Shi, Qin, Zhang, Guojun, Jiang, Liyan, Dong, Xiaorong, Gu, Kangsheng, Wang, Huijuan, Zhang, Xiaochun, Yang, Nong, Li, Yuping, Xiong, Jianping, Yi, Tienan, Peng, Min, Song, Yong, Fan, Yun, Cui, Jiuwei, Chen, Gongyan, Tan, Wei, Zang, Aimin, Guo, Qisen, Zhao, Guangqiang, Wang, Ziping, He, Jianxing, Yao, Wenxiu, Wu, Xiaohong, Chen, Kai, Hu, Xiaohua, Hu, Chunhong, Yue, Lu, Jiang, Da, Wang, Guangfa, Liu, Junfeng, Yu, Guohua, Li, Junling, Bai, Jianling, Xie, Wenmin, Zhao, Weihong, Wu, Lihong, Zhou, Caicun“…BACKGROUND: Lipusu is the first commercialized liposomal formulation of paclitaxel and has demonstrated promising efficacy against locally advanced lung squamous cell carcinoma (LSCC) in a small‐scale study. Here, we conducted a multicenter, randomized, phase 3 study to compare the efficacy and safety of cisplatin plus Lipusu (LP) versus cisplatin plus gemcitabine (GP) as first‐line treatment in locally advanced or metastatic LSCC. …”
Publicado 2021
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572663por Wilton, James, Wong, Stanley, Purssell, Roy, Abdia, Younathan, Chong, Mei, Karim, Mohammad Ehsanul, MacInnes, Aaron, Bartlett, Sofia R., Balshaw, Rob F., Gomes, Tara, Yu, Amanda, Alvarez, Maria, Dart, Richard C., Krajden, Mel, Buxton, Jane A., Janjua, Naveed Z.“…DESIGN, SETTING, AND PARTICIPANTS: A population-based, retrospective cohort study of individuals tested for HCV in British Columbia, Canada, with linkage to outpatient pharmacy dispensations, was conducted. Individuals with an initial HCV-negative test result followed by 1 additional test between January 1, 2000, and December 31, 2017, and who had no history of substance use at baseline (first HCV-negative test), were included. …”
Publicado 2022
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572664“…A retrospective analysis was conducted on the coincidence rate of the rapid intraoperative and routine postoperative pathological examinations of the 90 cases with GGNs. …”
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572665por Tayfur, Abdulhamit, Haque, Arman, Salles, Jose Inacio, Malliaras, Peter, Screen, Hazel, Morrissey, Dylan“…OBJECTIVE: Our objective was to investigate whether landing biomechanics among jumping athletes are associated with PT and can predict onset. METHODS: We conducted a systematic review with evidence gap map and meta-analysis. …”
Publicado 2021
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572666por Tufa, Tafese Beyene, Mackenzie, Colin R., Orth, Hans Martin, Wienemann, Tobias, Nordmann, Tamara, Abdissa, Sileshi, Hurissa, Zewdu, Schönfeld, Andreas, Bosselmann, Matthias, Häussinger, Dieter, Pfeffer, Klaus, Luedde, Tom, Fuchs, Andre, Feldt, Torsten“…Species identification and detection of resistance genes were conducted using MALDI-ToF MS (VITEK® MS) and PCR, respectively. …”
Publicado 2022
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572667por Li, Yiran, Guo, Yan, Hong, Y Alicia, Zeng, Yu, Monroe-Wise, Aliza, Zeng, Chengbo, Zhu, Mengting, Zhang, Hanxi, Qiao, Jiaying, Xu, Zhimeng, Cai, Weiping, Li, Linghua, Liu, Cong“…Generalized linear mixed effects models were conducted to investigate the dose–response relationships between patient engagement and outcomes. …”
Publicado 2022
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572668por Brody, Carinne, Chhoun, Pheak, Tuot, Sovannary, Fehrenbacher, Anne E, Moran, Alexander, Swendeman, Dallas, Yi, Siyan“…METHODS: A randomized controlled trial was conducted between March 2018 and June 2019 in the capital city and 3 other provinces in Cambodia. …”
Publicado 2022
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572669por Krepostman, N, Collins, M, Merchant, K, De Sirkar, S, Chan, L, Allen, S, Newman, J, Patel, D, Fareed, J, Berg, S, Darki, A“…PURPOSE: The objective of our study was to identify predictors of prolonged hospitalization, intensive care unit (ICU) admission, intubation, and death in patients infected with SARS-CoV-2. METHODS: We conducted a retrospective analysis of all patients hospitalized with SARS-CoV-2 at our health system that includes one tertiary care center and two community hospitals located in the Chicago metropolitan area. …”
Publicado 2021
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572670por Yusoff, N A, Ong, H S R, Cao, Y, Huang, Y H, Ang, T B, Loh, H F D, Foong, M M, Huang, W L, Oh, Y Z, Teo, Z W, Lee, S G S“…We hypothesized that the pandemic and lockdown restrictions (called a “circuit breaker (CB)”) will influence heart failure (HF) admission rates. METHODS: We conducted a retrospective analysis of patients who were admitted with a principal diagnosis of HF to a tertiary hospital in a SEA country. …”
Publicado 2021
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572671“…Inverse probability weighted (IPW) regressions and geotemporospatial regressions conducted for selected CAs. RESULTS: Data on 18,328,529 births from an aggregated population of 2,377,483,589 for mid-year analyses 2005–2013 comprehending 12,611 CARs for 62 CAs was assembled and ETOPFA-corrected (ETOPFACAR) where appropriate. …”
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572672“…A patient satisfaction survey on their knowledge about prescribed psychotropic medication was also conducted pre and post-intervention. RESULT: Results of Phase I and Phase 11 were compared. …”
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572673por Wölffer, Marcus, Battke, Florian, Schulze, Martin, Feldhahn, Magdalena, Flatz, Lukas, Martus, Peter, Forschner, Andrea“…We checked the data in view of potential associations between copy number variations (CNVs), small variations (VARs), human leucocyte antigen (HLA), sex, blood count parameters, pre-existing autoimmune diseases and the occurrence of IRAE. We conducted a literature research on genetic alterations hypothesized to be associated with the occurrence of IRAE. …”
Publicado 2022
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572674Publicado 2022“…BACKGROUND: The mental disorders included in the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 were depressive disorders, anxiety disorders, bipolar disorder, schizophrenia, autism spectrum disorders, conduct disorder, attention-deficit hyperactivity disorder, eating disorders, idiopathic developmental intellectual disability, and a residual category of other mental disorders. …”
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572675por Liu, Sophia, D’Amico, Davide, Shankland, Eric, Bhayana, Saakshi, Garcia, Jose M., Aebischer, Patrick, Rinsch, Chris, Singh, Anurag, Marcinek, David J.“…DESIGN, SETTING, AND PARTICIPANTS: This double-blind, placebo-controlled randomized clinical trial in adults aged 65 to 90 years was conducted at a medical center and a cancer research center in Seattle, Washington, from March 1, 2018, to July 30, 2020. …”
Publicado 2022
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572676por Kromydas, Theocharis, Campbell, Mhairi, Chambers, Stephanie, Boon, Michele Hilton, Pearce, Anna, Wells, Valerie, Craig, Peter“…The aim of the current research was to investigate inequality changes in children’s mental health and cognitive ability across the summer holidays. METHODS: We conducted linear and logistic regression analysis of mental health (borderline-abnormal total difficulty and prosocial scores on the strengths and difficulties questionnaire (SDQ)) and verbal cognitive ability (reading, verbal reasoning or vocabulary) at ages 7, 11 and 14, comparing UK Millennium Cohort Study members who were interviewed before and after the school summer holidays. …”
Publicado 2022
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572677por Thombre Kulkarni, Madhavi, Shafrir, Amy, Farland, Leslie V., Terry, Kathryn L., Whitcomb, Brian W., Eliassen, A. Heather, Bertone-Johnson, Elizabeth R., Missmer, Stacey A.“…Cumulative follow-up rate was greater than 90%, and participants continued follow-up until the onset of ENM, age 45 years, hysterectomy, oophorectomy, cancer diagnosis, death, loss to follow-up, or end of follow-up in May 2017, whichever occurred first. Data analyses were conducted from October 26, 2020, to April 27, 2021. …”
Publicado 2022
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572678por Anguita-Ruiz, Augusto, Zarza-Rebollo, Juan Antonio, Pérez-Gutiérrez, Ana M, Molina, Esther, Gutiérrez, Blanca, Bellón, Juan Ángel, Moreno-Peral, Patricia, Conejo-Cerón, Sonia, Aiarzagüena, Jose María, Ballesta-Rodríguez, M Isabel, Fernández, Anna, Fernández-Alonso, Carmen, Martín-Pérez, Carlos, Montón-Franco, Carmen, Rodríguez-Bayón, Antonina, Torres-Martos, Álvaro, López-Isac, Elena, Cervilla, Jorge, Rivera, Margarita“…An enrichment functional analysis was finally conducted with the aim of providing a general understanding of the biological pathways mapped by analyzed SNPs. …”
Publicado 2022
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572679por Bhaskaran, Krishnan, Rentsch, Christopher T., Hickman, George, Hulme, William J., Schultze, Anna, Curtis, Helen J., Wing, Kevin, Warren-Gash, Charlotte, Tomlinson, Laurie, Bates, Chris J., Mathur, Rohini, MacKenna, Brian, Mahalingasivam, Viyaasan, Wong, Angel, Walker, Alex J., Morton, Caroline E., Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M., Inglesby, Peter, Douglas, Ian J., McDonald, Helen I., Cockburn, Jonathan, Williamson, Elizabeth J., Evans, David, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen JW, Bacon, Sebastian, Smeeth, Liam, Goldacre, Ben“…METHODS AND FINDINGS: With the approval of NHS-England, we conducted a cohort study, using linked primary care and hospital data in OpenSAFELY to compare risks of hospital admission and death, overall and by specific cause, between people discharged from COVID-19 hospitalisation (February to December 2020) and surviving at least 1 week, and (i) demographically matched controls from the 2019 general population; and (ii) people discharged from influenza hospitalisation in 2017 to 2019. …”
Publicado 2022
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572680por Bachtiger, Patrik, Petri, Camille F, Scott, Francesca E, Ri Park, Se, Kelshiker, Mihir A, Sahemey, Harpreet K, Dumea, Bianca, Alquero, Regine, Padam, Pritpal S, Hatrick, Isobel R, Ali, Alfa, Ribeiro, Maria, Cheung, Wing-See, Bual, Nina, Rana, Bushra, Shun-Shin, Matthew, Kramer, Daniel B, Fragoyannis, Alex, Keene, Daniel, Plymen, Carla M, Peters, Nicholas S“…We aimed to test an artificial intelligence (AI) algorithm applied to a single-lead ECG, recorded during ECG-enabled stethoscope examination, to validate a potential point-of-care screening tool for LVEF of 40% or lower. METHODS: We conducted an observational, prospective, multicentre study of a convolutional neural network (known as AI-ECG) that was previously validated for the detection of reduced LVEF using 12-lead ECG as input. …”
Publicado 2022
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