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  1. 574221
    “…Since the risk score was low in the overall SURMOUNT-1 population, a subgroup analysis was conducted in participants with higher ASCVD risk at baseline (score≥7.5%, ACC/AHA intermediate-to-high risk). …”
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    SAT658 Tirzepatide Reduces The Predicted Risk Of Developing Atherosclerotic Cardiovascular Disease: A Post-hoc Analysis Of The Surmount-1 Trial
  2. 574222
    “…Methods and Study design: Secondary analysis of specimens obtained from a single-arm, open-label clinical trial (NCT01378299) on pharmacogenetics of response to T therapy conducted between 2011-2016 N=105 men (40-74 years old), with average morning T <300 ng/dL who were given intramuscular T cypionate 200 mg every 2 weeks for 18 months As earlier results from our lab, effect of T therapy is maximal after 6 months, we chose to study the specimens at baseline (BL) and 6 months (6M). …”
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    OR27-01 Upregulated Prdm16 Impairs Adipogenesis And Promotes Myogenesis Via PAX7 And Osteogenesis In Testosterone-treated Hypogonadal Men
  3. 574223
    “…To investigate the binding interactions between the core active components and key targets, we conducted docking studies using Chem3D, autoDock1.5.6, SYBYL2.0, and PYMOL2.4 software. …”
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    Molecular mechanism of Danshenol C in reversing peritoneal fibrosis: novel network pharmacological analysis and biological validation
  4. 574224
    “…Grants awarded to Zucker Hillside Hospital/Feinstein Institutes for Medical Research during the conduct of the brexanolone injection and zuranolone clinical trials (Sage Therapeutics), Consultant of: Sage Therapeutics, Inc., Brii Biosciences, Inc., and GH Research Ireland Limited, J. …”
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    Rapid improvements in MADRS with zuranolone in major depressive disorder and postpartum depression: results from the LANDSCAPE/NEST clinical development programmes
  5. 574225
    “…METHODS: A global Phase 3, multi-stage efficacy study (NCT04904549) among adults (≥18 years) was conducted in 53 research centres in eight countries (United States, Honduras, Japan, Colombia, Kenya, India, Ghana, Nepal). …”
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    Efficacy of a monovalent (D614) SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in adults: a phase 3, multi-country study
  6. 574226
    “…Subgroup analysis was conducted to examine whether the TyG index's association with mortality varied across different subgroups. …”
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    Association of triglyceride glucose index with all-cause and cardiovascular mortality in the general population
  7. 574227
    “…METHODS: This phase 2, randomized, observer-blind, placebo-controlled, dose-finding trial of mRNA-1647 was conducted in CMV-seronegative and -seropositive healthy adults aged 18-40 years (NCT04232280). …”
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    2892. Safety and Immunogenicity of mRNA-1647, an mRNA-Based Cytomegalovirus Vaccine in Healthy Adults: Results of a Phase 2, Randomized, Observer-Blind, Placebo-Controlled, Dose-Finding Trial
  8. 574228
    “…A secondary analysis of the data was conducted to assess impact of rapid testing on appropriateness of antibiotic spectrum by pathogen and resistance profile. …”
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    857. Impact of Rapid Antibiotic Susceptibility Testing for Gram Negative Bacteremia Varies by Pathogen Type and Resistance: A Secondary Analysis of the RAPIDS GN Trial
  9. 574229
    “…We assessed predictors of antiviral receipt for influenza in hospitalized children. METHODS: We conducted active, population-based surveillance of children presenting with fever or respiratory symptoms from December 1, 2016, to March 31, 2020, at seven children’s hospitals in the CDC NVSN. …”
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    1742. Predictors of Antiviral Receipt for Influenza in Hospitalized U.S. Children, New Vaccine Surveillance Network (NVSN), 2016–2020
  10. 574230
    “…Traveler-based2 and National SARS-CoV-2 Strain3 genomic surveillance data from the CDC and genomic surveillance conducted in VA for the U.S. and for ten HHS regions were used. …”
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    2292. Measuring Effectiveness against a Shifting Variant Landscape: COVID-19 Example in the Department of Veterans Affairs
  11. 574231
    “…BACKGROUND: Respiratory viruses are a substantial cause of hospitalization in infants and young children; less is known about their contribution to ARI-associated hospitalizations in children ≥ 5 years of age. METHODS: We conducted prospective, active surveillance among children ages 5–17 years hospitalized for acute respiratory illness (ARI) at 7 pediatric medical institutions comprising the New Vaccine Surveillance Network (NVSN) during December 1, 2016 through April 1, 2020. …”
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    1755. Hospitalizations for Respiratory Viruses among Children 5–17 Years of Age in the Pre-COVID-19 Pandemic Era, the New Vaccine Surveillance Network, 2016–2020
  12. 574232
    “…Bleeds occurred on days 1 (prior to vaccination), 8, 29, 90 and 180, and safety monitoring was conducted for 180d. An external comparison group of healthy adults who received a 4(th) dose booster of a licensed bivalent mRNA COVID vaccine were evaluated for immunogenicity. …”
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    377. Phase I trial of two novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as 4th dose boosters
  13. 574233
    “…A Pilot Study describes the treatment outcomes in group A. METHODS: We conducted a retrospective chart review of patients treated with Evusheld under EUA between January 18 and June 21, 2022, to assess their response to treatment by evaluating outcomes listed in Figure 2. …”
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    493. ENDURANCE - EffectiveNess of Evusheld for COVID-19 Pre-exposUre PRophylAxis iN ImmunoCompromised PatiEnts – A Pilot Study
  14. 574234
    “…BACKGROUND: The EnACT trial was a phase 2 randomized clinical trial conducted in Uganda, which evaluated a novel orally delivered lipid nanocrystal (LNC) amphotericin B for treatment of cryptococcal meningitis. …”
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    829. 5-Flucytosine Longitudinal Antifungal Susceptibility Testing of Cryptococcus neoformans: A Sub-study of the EnACT Trial Testing Oral Amphotericin
  15. 574235
    “…The host-response pathways associated with the progression to severe influenza disease and mechanisms of vaccination on mitigating illness severity are not well understood. METHODS: We conducted a prospective study of children aged 2 to 18 years hospitalized with PCR-confirmed influenza infection from 2020-2022. …”
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    301. Immune Responses to Influenza Infection in Hospitalized Children Using Transcriptomics
  16. 574236
    “…PROBLEM/CONDITION: CDC conducts abortion surveillance to document the number and characteristics of women obtaining legal induced abortions and number of abortion-related deaths in the United States. …”
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    Abortion Surveillance — United States, 2021
  17. 574237
    “…Flow cytometry assays were conducted to assess apoptosis rates and the G1/S ratio in the cell cycle. …”
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    Upregulated PARP1 confers breast cancer resistance to CDK4/6 inhibitors via YB-1 phosphorylation
  18. 574238
    “…DESIGN: Modified Delphi method with a consensus conference of 55 international experts, several subsequent meetings of subgroups and key individuals, teleconferences, and electronic-based discussion among subgroups and among the entire committee. This process was conducted independently of any industry funding. METHODS: We used the GRADE system to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations. …”
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    Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
  19. 574239
    “…Separate analyses were conducted for participants in the original sample (n = 575) and those who completed both posttests (n = 278). …”
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    Effectiveness of a Web-Based Brief Alcohol Intervention and Added Value of Normative Feedback in Reducing Underage Drinking: A Randomized Controlled Trial
  20. 574240
    “…We analyzed data from 1607 towed-diver surveys (>1 ha transects surveyed by observers towed behind a boat) conducted at 46 reefs in the central-western Pacific Ocean, reefs that included some of the world's most pristine coral reefs. …”
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    Re-Creating Missing Population Baselines for Pacific Reef Sharks
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