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574661“…METHODS/STUDY POPULATION: A retrospective cohort analysis was conducted using the ACS-NSQIP database from 2005 to 2017. …”
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574662por Iwata, Nakao, Ishigooka, Jun, Naoi, Ichiro, Matsumoto, Masahiro, Kanamori, Yuichi, Nakamura, Hiroshi, Higuchi, Teruhiko“…METHODS: An open-label study was conducted in adults with schizophrenia at 37 sites in Japan. …”
Publicado 2019
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574663por Abdullahi, Leila H, Kagina, Benjamin M, Ndze, Valantine Ngum, Hussey, Gregory D, Wiysonge, Charles S“…Twelve studies were conducted in the USA, while there was one study each from: Australia, Sweden, Tanzania, and the UK. …”
Publicado 2020
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574664por Barnabas, Ruanne V., Brown, Elizabeth, Bershteyn, Anna, Miller, R. Scott, Wener, Mark, Celum, Connie, Wald, Anna, Chu, Helen, Wesche, David, Baeten, Jared M.“…This multisite trial will be conducted at seven sites in Seattle (UW), Los Angeles (UCLA), New Orleans (Tulane), Baltimore (UMB), New York City (NYU), Syracuse (SUNY-Upstate), and Boston (BMC). …”
Publicado 2020
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574665por Sivapalan, Pradeesh, Ulrik, Charlotte Suppli, Bojesen, Rasmus Dahlin, Lapperre, Therese Sophie, Eklöf, Josefin Viktoria, Håkansson, Kjell Erik Julius, Browatzki, Andrea, Tidemansen, Casper, Wilcke, Jon Torgny, Janner, Julie, Gottlieb, Vibeke, Meteran, Howraman, Porsbjerg, Celeste, Madsen, Birgitte Lindegaard, Moberg, Mia, Pedersen, Lars, Benfield, Thomas Lars, Lundgren, Jens Dilling, Knop, Filip Krag, Biering-Sørensen, Tor, Ghanizada, Muzhda, Sonne, Tine Peick, Bødtger, Uffe Christian Steinholtz, Jensen, Sidse Graff, Rasmussen, Daniel Bech, Brøndum, Eva, Tupper, Oliver Djurhuus, Sørensen, Susanne Wiemann, Alstrup, Gitte, Laursen, Christian Borbjerg, Møller, Ulla Weinrich, Sverrild, Asger, Jensen, Jens-Ulrik Stæhr“…Fertile women* must not be pregnant, i.e. negative pregnancy test must be available at inclusion • Informed consent signed by the patient *Defined as after menarche and until postmenopausal (no menstruation for 12 months) Exclusion criteria: • At the time of recruitment, the patient uses >5 LO2/min (equivalent to 40% FiO2 if measured) • Known intolerance/allergy to azithromycin or hydroxychloroquine or hypersensitivity to quinine or 4-aminoquinoline derivatives • Neurogenic hearing loss • Psoriasis • Retinopathy • Maculopathy • Visual field changes • Breastfeeding • Severe liver diseases other than amoebiasis (INR> 1.5 spontaneously) • Severe gastrointestinal, neurological and hematological disorders (investigator-assessed) • eGFR <45 ml/min/1.73 m2 • Clinically significant cardiac conduction disorders/arrhythmias or prolonged QTc interval (QTc (f) of> 480/470 ms). • Myasthenia gravis • Treatment with digoxin* • Glucose-6-phosphate dehydrogenase deficiency • Porphyria • Hypoglycaemia (Blood glucose at any time since hospitalization of <3.0 mmol/L) • Severe mental illness which significantly impedes cooperation • Severe linguistic problems that significantly hinder cooperation • Treatment with ergot alkaloids *The patient must not be treated with digoxin for the duration of the intervention. …”
Publicado 2020
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574666por Chen, Xinxia, Kong, Linghua, Piltonen, Terhi T, Gissler, Mika, Lavebratt, Catharina“…Particularly, the risk was increased for sleeping disorders (HR 1.46; 95% CI 1.27–1.67), attention-deficit/hyperactivity disorders and conduct disorders (HR 1.42; 95% CI 1.33–1.52), tic disorders (HR 1.42; 95% CI 1.21–1.68), intellectual disabilities (HR 1.41; 95% CI 1.24–1.60), autism spectrum disorder (HR 1.40; 95% CI 1.26–1.57), specific developmental disorders (HR 1.37; 95% CI 1.30–1.43), eating disorders (HR 1.36; 95% CI 1.15–1.61), anxiety disorders (HR 1.33; 95% CI 1.26–1.41), mood disorders (HR 1.27; 95% CI 1.18–1.35) and other behavioral and emotional disorders (ICD-10 F98, HR 1.49; 95% CI 1.39–1.59). …”
Publicado 2020
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574667por Marty, Francisco M, Malhotra, Prashant, Gottlieb, Robert L, Tashima, Karen T, Galli, Massimo, Chai, Louis Yi Ann, SenGupta, Devi, Hyland, Robert H, Wang, Hongyuan, Zhong, Lijie, Cao, Huyen, Chokkalingam, Anand, Osinusi, Anu, Brainard, Diana M, Brown, Michael, Goikoetxea, Ane Josune, Jain, Mamta, Hui, David Shu Cheong, Bernasconi, Enos, Spinner, Christoph“…Its effect in patients with moderate COVID-19 remains unclear. METHODS: We conducted an open-label, phase 3 trial (NCT04252664) involving hospitalized patients with confirmed SARS-CoV-2 infection, evidence of pulmonary infiltrates, and oxygen saturation >94% on room air. …”
Publicado 2020
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574668por Juul, Sophie, Nielsen, Emil Eik, Feinberg, Joshua, Siddiqui, Faiza, Jørgensen, Caroline Kamp, Barot, Emily, Holgersson, Johan, Nielsen, Niklas, Bentzer, Peter, Veroniki, Areti Angeliki, Thabane, Lehana, Bu, Fanlong, Klingenberg, Sarah, Gluud, Christian, Jakobsen, Janus Christian“…METHODS AND FINDINGS: We planned to conduct aggregate data meta-analyses, trial sequential analyses, network meta-analysis, and individual patient data meta-analyses. …”
Publicado 2021
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574669“…SETTING: This study was conducted from January 2012 to December 2016 in a single tertiary IBD center. …”
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574670“…Then double immunofluorescence was conducted to verify the overexpression of S100A6 protein in intrahepatic bile duct cells of BDL mice. …”
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574671por Shi, Chunhu, Dumville, Jo C, Cullum, Nicky, Rhodes, Sarah, Leung, Vannessa, McInnes, Elizabeth“…Almost all studies were conducted in the regions of Europe and America. Of the 17 included studies, two (223 participants) compared reactive air surfaces with surfaces that were not well described and therefore could not be classified. …”
Publicado 2021
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574672“…Almost all studies were conducted in Europe and America. Of the 20 studies, 11 (2826 participants) included surfaces that were not well described and therefore could not be fully classified. …”
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574673por Vonasek, Bryan, Ness, Tara, Takwoingi, Yemisi, Kay, Alexander W, Wyk, Susanna S, Ouellette, Lara, Marais, Ben J, Steingart, Karen R, Mandalakas, Anna M“…Studies were eligible if conducted for screening rather than diagnosing tuberculosis. …”
Publicado 2021
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574674por Abdelaal, Mahmoud A.Z., Abdelrahman, Dyala, Cengiz, Mahir, Yavuzer, Hakan, Yavuzer, Serap, Bien, Ivy, Bhuva, Preeti, Pham, Jessica V, Siu, Royal, Tang, Mengdi, Ward, Ashley, Goodrow, Jason, Ludlum, Peter, Stark, Charles W., Perrine, Susan P.“…We focused on contributors to cytokine storm and acute respiratory distress syndrome (ARDS), the leading causes of mortality in COVID-19 (Huang, Lancet, 2020). We also conducted a clinical trial in hospitalized COVID-19 patients on ESPEN-recommended nutrition +/- GLN. …”
Publicado 2020
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574675por Vijenthira, Abi, Gong, Inna, Fox, Thomas A, Booth, Stephen, Cook, Gordon, Fattizzo, Bruno, Martín Moro, Fernando, Razanamahery, Jerome, Riches, John, Zwicker, Jeffrey I., Patell, Rushad, Vekemans, Marie Christiane, Scarfo, Lydia, Chatzikonstantinou, Thomas, Yildiz, Halil, Lattenist, Raphael, Mantzaris, Ioannis, Wood, William, Hicks, Lisa K.“…Sensitivity analyses were conducted on the primary outcomes limiting to studies with low risk of bias, and to studies including both outpatients and hospitalized patients. …”
Publicado 2020
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574676por Halford, Sarah, Wan, Susan, Dragoni, Ilaria, Silvester, Julie, Nazarov, Bobojon, Anthony, Daniel, Anthony, Suzie, Ladds, Emma, Norrie, John, Dhaliwal, Kevin“…A formal interim analysis will be performed once 50% of the maximum sample size has been recruited PARTICIPANTS: The trial will recruit adults (≥ 18 years) who score moderate to very high risk according to COVID-age risk calculation, with typical symptoms of COVID-19 infection as per Public Health England guidance or equivalent organisations in the UK, Health Protection Scotland, Public Health Wales, Public Health Agency (Northern Ireland) and with evidence of current COVID-19 infection from a validated assay. The trial is being conducted in the UK and patients are recruited through primary care and hospital settings. …”
Publicado 2021
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574677por Dudani, Shaan, Marginean, Horia, Gotfrit, Joanna, Tang, Patricia A., Monzon, Jose Gerard, Dennis, Kristopher, Kennecke, Hagen F., Powell, Erin D., Babak, Sam, Cheung, Winson Y., Vickers, Michael M.“…SETTINGS: This study was conducted at academic and community cancer centers participating in the Canadian Health Outcomes Research Database Consortium Rectal Cancer Database. …”
Publicado 2021
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574678por Llata, Eloisa, Cuffe, Kendra M., Picchetti, Viani, Braxton, Jimmy R., Torrone, Elizabeth A.“…SSuN is a collaboration of competitively selected state and city health departments that conduct facility-based sentinel surveillance in STD clinics. …”
Publicado 2021
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574679por Deng, Zhe, Teng, Yong-Jie, Zhou, Qing, Ouyang, Zhao-Guang, Hu, Yu-Xing, Long, Hong-Ping, Hu, Mei-Jie, Mei, Si, Lin, Feng-Xia, Dai, Xin-Jun, Zhang, Bo-Yu, Feng, Ting, Tian, Xue-Fei“…An immunofluorescence assay was conducted to examine the expression of CD4+ T cells and CD8+ T cells. …”
Publicado 2021
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574680por Cicin-Sain, Caroline, Huang, Alice, Pasin, Chloe, Epp, Selina, Mueller, Nicolas J, Nilsson, Jakob, Vilinovszki, Oliver, Nair, Gayathri, Wolfensberger, Nathan, Hockl, Philipp, Schanz, Urs, Trkola, Alexandra, Kouyos, Roger, Hasse, Barbara, Zinkernagel, Annelies, Manz, Markus G, Abela, Irene A, Mueller, Antonia MS“…However, pivotal studies have been conducted in healthy volunteers, while recipients of allogeneic hematopoietic cell transplantations (allo-HCT) may have different dynamics and patterns of response to the vaccine and data in this cohort is lacking. …”
Publicado 2021
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