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86461por Braun, Sascha D., Monecke, Stefan, Thürmer, Alexander, Ruppelt, Antje, Makarewicz, Oliwia, Pletz, Mathias, Reißig, Annett, Slickers, Peter, Ehricht, Ralf“…In direct comparison, the microarray correctly identified 98.2% of the covered carbapenemase genes. This included blaVIM (13 out of 13), blaGIM (2/2), blaKPC (27/27), blaNDM (5/5), blaIMP-2/4/7/8/13/14/15/16/31 (10/10), blaOXA-23 (12/13), blaOXA-40-group (7/7), blaOXA-48-group (32/33), blaOXA-51 (1/1) and blaOXA-58 (1/1). …”
Publicado 2014
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86462por Philpott, Martin, Rogers, Catherine M, Yapp, Clarence, Wells, Chris, Lambert, Jean-Philippe, Strain-Damerell, Claire, Burgess-Brown, Nicola A, Gingras, Anne-Claude, Knapp, Stefan, Müller, Susanne“…CONCLUSIONS: Viable FRAP assays were established for 11 representative bromodomain-containing proteins that broadly cover the bromodomain phylogenetic tree. Addition of SAHA can overcome weak binding to chromatin, and the use of tandem bromodomain constructs can eliminate masking effects of other chromatin binding domains. …”
Publicado 2014
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86463por Córdoba-Doña, Juan Antonio, San Sebastián, Miguel, Escolar-Pujolar, Antonio, Martínez-Faure, Jesús Enrique, Gustafsson, Per E“…Suicide attempts occurring between 2003 and 2012 were included, in order to cover five years prior to the crisis (2003–2007) and five years after its onset (2008–2012). …”
Publicado 2014
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86464“…Unlike full reading, ‘skim-reading’ involves the process of looking quickly over information in an attempt to cover more material whilst still being able to retain a superficial view of the underlying content. …”
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86465por López-Abente, Gonzalo, Aragonés, Nuria, Pérez-Gómez, Beatriz, Pollán, Marina, García-Pérez, Javier, Ramis, Rebeca, Fernández-Navarro, Pablo“…RESULTS: The mortality patterns observed for stomach, colorectal and lung cancer were maintained over the 20 years covered by the study. Prostate cancer and the tumours studied in women showed no defined spatial pattern, with the single exception of stomach cancer. …”
Publicado 2014
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86466por Chau, Josephine Y, Daley, Michelle, Srinivasan, Anu, Dunn, Scott, Bauman, Adrian E, van der Ploeg, Hidde P“…After the four week intervention, participants shared their perceptions and experiences of using the sit-stand workstation in focus group interviews with 4–5 participants. Topics covered in the focus groups included patterns of workstation use, barriers and facilitators to standing while working, effects on work performance, physical impacts, and feasibility in the office. …”
Publicado 2014
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86467por Samarakoon, Pubudu Saneth, Sorte, Hanne Sørmo, Kristiansen, Bjørn Evert, Skodje, Tove, Sheng, Ying, Tjønnfjord, Geir E, Stadheim, Barbro, Stray-Pedersen, Asbjørg, Rødningen, Olaug Kristin, Lyle, Robert“…The goal of our study was to develop a protocol to detect exonic CNVs (including shorter CNVs that cover 1–4 exons), combining computational prediction algorithms and a high-resolution custom CGH array. …”
Publicado 2014
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86468por Olesen, Christinna Rebecca, Nielsen, Jane Hyldgaard, Mortensen, Rikke Nørmark, Bøggild, Henrik, Torp-Pedersen, Christian, Overgaard, Charlotte“…METHOD: In Danish national registers covering the years 1994–2011 we identified 2171 birthing women whose pregnancy was complicated by first-time gestational diabetes. …”
Publicado 2014
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86469por Pujades-Rodriguez, Mar, Timmis, Adam, Stogiannis, Dimitris, Rapsomaniki, Eleni, Denaxas, Spiros, Shah, Anoop, Feder, Gene, Kivimaki, Mika, Hemingway, Harry“…METHODS: Record-linkage cohort study of 1.93 million people to examine the association between small-area socioeconomic deprivation and 12 CVDs. Health records covered primary care, hospital admissions, a myocardial infarction registry and cause-specific mortality in England (CALIBER). …”
Publicado 2014
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86470“…METHODS: To extend posterior spinal fusion to the sacrum, we used either 1 Harrington rod and 1 Luque L rod with sublaminar wires in 14 patients (Group 1) or two rods with sublaminar wires in 51 patients (Group 2) along with abundant autograft and allograft bone covering the ends of the rods. RESULTS: Diagnoses were Duchenne muscular dystrophy 53, spinal muscular atrophy 4, myopathy 3, limb girdle muscular dystrophy 2, infantile FSH muscular dystrophy 1, cerebral palsy 1, and Friedreich ataxia 1. …”
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86471por Lee, Clara N, Wetschler, Matthew H, Chang, Yuchiao, Belkora, Jeffrey K, Moy, Beverly, Partridge, Ann, Sepucha, Karen R“…Most providers reported that the knowledge items covered essential content. Two of the five goal items had a ceiling effect, and one goal had low content validity. …”
Publicado 2014
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86472“…The Po plain woodlands which once covered the whole Plain, today are reduced in isolated highly threatened remnants by modern intensive agriculture. …”
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86473por Lorenz, Julia, Seebach, Elisabeth, Hackmayer, Gerit, Greth, Carina, Bauer, Richard J., Kleinschmidt, Kerstin, Bettenworth, Dominik, Böhm, Markus, Grifka, Joachim, Grässel, Susanne“…Unchallenged Mc1re/e mice display smaller articular cartilage covered area without OA-related surface erosions indicating that MC1-signaling is critical for proper cartilage matrix integrity and formation. …”
Publicado 2014
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86474“…The primary outcome measure will assess upper extremity functioning (Patient-Rated Wrist Evaluation [PRWE]), while secondary outcome measures cover subjective wrist function (Disabilities of the Arm and Shoulder; [DASH], objective impairment (range of motion, grip force) and quality of life (EuroQol-5D, [EQ5D]). …”
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86475por Hsu, Hung-Te, Chou, Shah-Hwa, Chou, Chun-Yen, Tseng, Kuang-Yi, Kuo, Yi-Wei, Chen, Mei-Chun, Cheng, Kuang-I“…They were prospectively randomized into one of two groups: those intubated with a DLT angled to conceal the tracheal orifice (the tracheal orifice-covered, TOC) group or the tracheal orifice-exposed (TOE) group. …”
Publicado 2014
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86476“…METHODS: Seven different tube-restraint combinations were compared against themselves and one another at a series of discrete angles (test points) covering a hemisphere on the plane of the face. Force values for tube motion of 2 cm and 5 cm (or failure) were recorded for 3 pull tests, at each angle, for each method of tube fixation. …”
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86477por Merz, Kenneth M.“…Car–Parrinello or Born–Oppenheimer molecular dynamics approaches address the short time scale sampling issue, but how to effectively use QM to study phenomenon covering longer time scales will be the focus of future research. …”
Publicado 2014
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86478“…RESULTS: Using 1,270 post-mortem central nervous system tissue samples from 13 patient cohorts covering four neurodegenerative diseases, we identified 243 differentially expressed genes, which were similarly dysregulated in 15 additional patient cohorts of 205 samples including seven neurodegenerative diseases. …”
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86479por Feurstein, Simone, Rücker, Frank G, Bullinger, Lars, Hofmann, Winfried, Manukjan, Georgi, Göhring, Gudrun, Lehmann, Ulrich, Heuser, Michael, Ganser, Arnold, Döhner, Konstanze, Schlegelberger, Brigitte, Steinemann, Doris“…Genomic profiling led to the minimal deleted region covering the 3′-UTR of ETV6 and CDKN1B. Direct sequencing revealed one novel monoallelic frameshift mutation in ETV6 while no mutations in CDKN1B were identified. …”
Publicado 2014
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86480por Bening, Constanze, Mehlhorn, Uwe, Conzelmann, Lars Oliver, Stumpf, Nicole, Sikand, Anjuli, Vahl, Christian-Friedrich“…Calcium sensitivity is higher compared to the non-myxomatous group, which might be a compensatory mechanism to cover the physiological demand. Furthermore we suggest a higher incidence of diastolic dysfunction in patients with myxomatous mitral valve degeneration, which might have an impact on ventricular remodeling after mitral valve surgery.…”
Publicado 2014
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