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28861por Zhong, Jingyi, Zhong, Chenghui, Qiu, Lan, Li, Jiayi, Lai, Jiayi, Lu, Wenfeng, Wang, Shuguang, Zhong, Jiacai, Zhao, Jing, Zhou, Yun“…We further developed a new score to simplify the assessment of anxiety during COVID-19 crisis. RESULTS: Among 19,802 participants, we found that those who were front-line medical personnel, suffered from chronic disease, with present symptoms of SARS-CoV-2 infection or contact history had 112, 93, 40 and 15% increased risk of higher anxiety level; while those with knowledge about personal protective measures or wore masks had 75 and 29% lower risk of higher anxiety level respectively. …”
Publicado 2021
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28862por Völkel, Gunnar, Fürstberger, Axel, Schwab, Julian D, Werle, Silke D, Ikonomi, Nensi, Gscheidmeier, Thomas, Kraus, Johann M, Groß, Alexander, Holderried, Martin, Balig, Julien, Jobst, Franz, Kuhn, Peter, Kuhn, Klaus A, Kohlbacher, Oliver, Kaisers, Udo X, Seufferlein, Thomas, Kestler, Hans A“…BACKGROUND: Overcoming the COVID-19 crisis requires new ideas and strategies for online communication of personal medical information and patient empowerment. …”
Publicado 2021
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28863por Paez, Diana, Mikhail-Lette, Miriam, Gnanasegaran, Gopinath, Dondi, Maurizio, Estrada-Lobato, Enrique, Bomanji, Jamshed, Vinjamuri, Sobhan, El-Haj, Noura, Morozova, Olga, Alonso, Omar, Pellet, Olivier, Orellana, Pilar, Navarro, Maria C., Delgado Bolton, Roberto C., Giammarile, Francesco“…To best navigate the future, NM must continue to learn from this crisis and must continue to bring new questions, evidence, ideas, and warranted systematic updates to the figurative table.…”
Publicado 2022
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28864por Lee, Linda Yin-king, Chan, Issac Chun-wing, Wong, Owen Pak-man, Ng, Yaki Hoi-ying, Ng, Crystal Kit-ying, Chan, Max Hin-wa, Ng, Joe Ka-chun, Koo, Hailey Hei-tung, Lam, Suk-ting, Chu, Ada Cho-wai, Wong, Rachel Yuen-shan, Leung, Heidi Po-ying, Pun, Angel Lok-ching“…This study aimed to examine the practice of reusing face masks among adults in Hong Kong during the COVID-19 pandemic and its association with their health beliefs toward this health crisis. METHODS: A cross-sectional descriptive study was conducted. …”
Publicado 2021
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28865por Makali, Samuel Lwamushi, Malembaka, Espoir Bwenge, Lambert, Anne-Sophie, Karemere, Hermès Bimana, Eboma, Christian Molima, Mwembo, Albert Tambwe, Ssali, Steven Barnes, Balaluka, Ghislain Bisimwa, Donnen, Phillippe, Macq, Jean“…CONCLUSIONS: Armed conflicts have a significantly negative impact on people’s perceived health, particularly in crisis health zones. In this area, we must accentuate actions aiming to strengthen people’s psychosocial well-being.…”
Publicado 2021
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28866por Lambraki, Irene Anna, Majowicz, Shannon Elizabeth, Parmley, Elizabeth Jane, Wernli, Didier, Léger, Anaïs, Graells, Tiscar, Cousins, Melanie, Harbarth, Stephan, Carson, Carolee, Henriksson, Patrik, Troell, Max, Jørgensen, Peter Søgaard“…BACKGROUND: Antimicrobial resistance (AMR) is an escalating global crisis with serious health, social, and economic consequences. …”
Publicado 2021
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28867“…During the hospitalization showed bilateral nephrocalcinosis, hypercalcemic crisis. She has a background of total thyroidectomy and subtotal parathyroidectomy because a thyroid adenomatous hyperplasia and parathyroid hyperplasia with removal of a total of three parathyroid glands. …”
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28868“…INTRODUCTION: The COVID-19 pandemic led to an international health crisis and restrictions. While the phenotype associated with COVID-19 severity in people with diabetes has rapidly been explored, the impact of restrictive measures, including lockdown, and tertiary care disruption on metabolic control and access to healthcare remained unknown. …”
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28869por Beetz, Oliver, Thies, Juliane, Weigle, Clara A., Ius, Fabio, Winkler, Michael, Bara, Christoph, Richter, Nicolas, Klempnauer, Jürgen, Warnecke, Gregor, Haverich, Axel, Avsar, Murat, Grannas, Gerrit“…Thus, we advocate for a “kidney-after-heart” program in such patients to ensure responsible and reasonable utilization of scarce resources in times of ongoing organ shortage crisis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12882-021-02430-x.…”
Publicado 2021
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28870por Ames-Guerrero, Rita J., Barreda-Parra, Victoria A., Huamani-Cahua, Julio C., Banaszak-Holl, Jane“…Its rapid spread has overwhelmed populations in all corners of Latin-American countries resulting in individual psychological reactions that may aggravate the health crisis. This study reports on demographics, self-reported psychological disturbances and associated coping styles during the COVID-19 pandemic for the Peruvian population. …”
Publicado 2021
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28871por Siewe Fodjo, Joseph Nelson, Ngarka, Leonard, Njamnshi, Wepnyu Y., Nfor, Leonard N., Mengnjo, Michel K., Mendo, Edwige Laure, Angwafor, Samuel A., Atchou Basseguin, Jonas Guy, Nkouonlack, Cyrille, Njit, Edith N., Ahidjo, Nene, Chokote, Eric S., Dema, Fidèle, Fonsah, Julius Y., Tatah, Godwin Y., Palmer, Nancy, Seke Etet, Paul F., Palmer, Dennis, Nsagha, Dickson S., Etya’ale, Daniel E., Perrig, Stephen, Sztajzel, Roman, Annoni, Jean-Marie, Zoung-Kanyi Bissek, Anne-Cécile, Leke, Rose G. F., Abena Ondoa Obama, Marie-Thérèse, Nkengasong, John N., Colebunders, Robert, Njamnshi, Alfred K.“…CONCLUSION: Depression amidst the COVID-19 crisis is less prevalent in Cameroon than in other countries. …”
Publicado 2021
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28872por Giannakopoulos, George, Mylona, Savvina, Zisimopoulou, Anastasia, Belivanaki, Maria, Charitaki, Stella, Kolaitis, Gerasimos“…RESULTS: Regarding their knowledge of the impact of the current pandemic, almost all adolescents focused on information about the nature of coronavirus and on existing crisis management practices. Almost all patients identified predominantly negative changes due to the quarantine state, including restrictions on both social life and personal freedom as well as excessive contact with family members during home isolation. …”
Publicado 2021
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28873por Aljouie, Abdulrhman Fahad, Almazroa, Ahmed, Bokhari, Yahya, Alawad, Mohammed, Mahmoud, Ebrahim, Alawad, Eman, Alsehawi, Ali, Rashid, Mamoon, Alomair, Lamya, Almozaai, Shahad, Albesher, Bedoor, Alomaish, Hassan, Daghistani, Rayyan, Alharbi, Naif Khalaf, Alaamery, Manal, Bosaeed, Mohammad, Alshaalan, Hesham“…CONCLUSION: The experimental results demonstrate the practicality of the proposed COVID-19 predictive tool for hospital resource planning and patients’ prioritization in the current COVID-19 pandemic crisis.…”
Publicado 2021
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28874por Liu, Ming, Wu, Na, Xu, Keman, Saaoud, Fatma, Vasilopoulos, Eleni, Shao, Ying, Zhang, Ruijing, Wang, Jirong, Shen, Haitao, Yang, William Y., Lu, Yifan, Sun, Yu, Drummer, Charles, Liu, Lu, Li, Li, Hu, Wenhui, Yu, Jun, Praticò, Domenico, Sun, Jianxin, Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng“…To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. Similarly, sepsis and trauma plus organ failures upregulated seven OCRG groups including vesicle, MT fission, mitophagy, sarcoplasmic reticulum–MT, MT fusion, autophagosome–lysosome fusion, and autophagosome/endosome–lysosome fusion, classified as the cell failure-handling OCRGs; (3) suppression of autophagosome–lysosome fusion in endothelial and epithelial cells is required for viral replications, which classify this decreased group as the viral replication-suppressed OCRGs; (4) pro-atherogenic damage-associated molecular patterns (DAMPs) such as oxidized low-density lipoprotein (oxLDL), lipopolysaccharide (LPS), oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (oxPAPC), and interferons (IFNs) totally upregulated 33 OCRGs in endothelial cells (ECs) including vesicle, MT fission, mitophagy, MT fusion, endoplasmic reticulum (ER)–MT contact, ER– plasma membrane (PM) junction, autophagosome/endosome–lysosome fusion, sarcoplasmic reticulum–MT, autophagosome–endosome/lysosome fusion, and ER–Golgi complex (GC) interaction as the 10 EC-activation/inflammation-promoting OCRG groups; (5) the expression of OCRGs is upregulated more than downregulated in regulatory T cells (Tregs) from the lymph nodes, spleen, peripheral blood, intestine, and brown adipose tissue in comparison with that of CD4(+)CD25(−) T effector controls; (6) toll-like receptors (TLRs), reactive oxygen species (ROS) regulator nuclear factor erythroid 2-related factor 2 (Nrf2), and inflammasome-activated regulator caspase-1 regulated the expressions of OCRGs in diseases, virus-infected cells, and pro-atherogenic DAMP-treated ECs; (7) OCRG expressions are significantly modulated in all the 28 cancer datasets, and the upregulated OCRGs are correlated with tumor immune infiltrates in some tumors; (8) tumor promoter factor IKK2 and tumor suppressor Tp53 significantly modulate the expressions of OCRGs. …”
Publicado 2021
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28875por Marchand, Kirsten, Tallon, Corinne, Katan, Christina, Fairbank, Jill, Fogarty, Oonagh, Pellatt, Katrina Marie, Turuba, Roxanne, Mathias, Steve, Barbic, Skye“…BACKGROUND: Opioid use is one of the most critical public health issues as highly potent opioids contribute to rising rates of accidental opioid-related toxicity deaths. This crisis has affected people from all age groups, including youth (ages 15–24) who are in a critical developmental period where the stakes of opioid use are especially high. …”
Publicado 2021
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28876por Giampaolo, Rosaria, Marotta, Rosaria, Biagiarelli, Francesco Saverio, Zampa, Antonella, Moramarco, Stefania, Buonomo, Ersilia“…This exacerbating condition highlights the need of better assisting this fragile population that is at most risk of poverty, food insecurity and social exclusion in Italy, particularly during this pandemic crisis.…”
Publicado 2021
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28877por Kwaghe, Ayi Vandi, Ilesanmi, Olayinka Stephen, Amede, Peter Okpeh, Okediran, James Olatunde, Utulu, Rowland, Balogun, Muhammad Shakir“…BACKGROUND: COVID-19 pandemic has resulted in global health and economic crisis. We investigated the experiences of frontline health care workers recovering from COVID-19 in Lagos State Nigeria. …”
Publicado 2021
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28878por Wozniaki, Natalia, Lacerda, Marcelo Pitombeira, Baptista, JoãoPedro Ribeiro, Cassi, Helio Vida, Neves, Gabriela Duarte, Boettcher, Ivan Schneider, Dall’Oglio, Ana Claudia, Tavares, Fabiana Sanchez, Gastal, Gabriela Roncone, Schwingel, Fabiano Luis“…CONTEXT: COVID-19 has become the largest health crisis in recent history, with complex healthcare challenges in frontline and critical care settings or in assisting patients with chronic diseases and cancer. …”
Publicado 2021
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28879por Parabhoi, Lambodara, Sahu, Ramani Ranjan, Dewey, Rebecca Susan, Verma, Manoj Kumar, Kumar Seth, Arbind, Parabhoi, Damodar“…This limitation needs to be addressed so that the vital distribution services offered by platforms like YouTube can be fully utilized for increasing public understanding of healthcare science, particularly during a crisis such as a pandemic.…”
Publicado 2021
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28880por Gorton, H. C., Macfarlane, H., Edwards, R., Farid, S., Garner, E., Mahroof, M., Rasul, S., Keating, D., Zaman, H., Scott, J., Maidment, I., Strawbridge, J.“…MPharm programmes need sufficient focus on real-world skills such as communication and crisis response, to complement the fundamental science. …”
Publicado 2021
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