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  1. 302001
    “…Malignant degeneration and infertility are two critical points in terms of treatment. Early diagnosis with increased awareness is essential in preserving fertility and preventing malignant degeneration.…”
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    Persistent Mullerian duct syndrome: An atypical clinical presentation
  2. 302002
    “…Familial hyperphosphatemic TC, which will be presented in this case, causes by relative deficiency or resistance of FGF-23, which is the critical regulatory hormone in the phosphorus metabolism. …”
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    A rare disease: Familial hyperphosphatemic tumoral calcinosis
  3. 302003
    “…As a result, determining the readiness of health facilities that offer FP services is critical for identifying weaknesses and opportunities for continued development of FP health systems in those regions. …”
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    Assessing the readiness of health facilities to provide family planning services in low-resource settings: Insights from nationally representative service provision assessment surveys in 10 Countries
  4. 302004
    “…CONCLUSIONS: Few scoring systems, including proposed ones, had high AUCs, sensitivity, and reasonable specificities, which could potentially aid in safely selecting adult patients with acute appendicitis for nonoperative management. CRITICAL RELEVANCE STATEMENT: The study suggests few scoring systems for predicting complicated appendicitis with high AUCs and reasonable sensitivities, potentially aiding in selecting patients for nonoperative management. …”
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    Validation of scoring systems for the prediction of complicated appendicitis in adults using clinical and computed tomographic findings
  5. 302005
    “…The AgF application could be easily implemented into the training program of Indigenous health workers and yield critical information in the management armamentarium of health and well-being recommendations for Australia’s First Peoples. …”
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    A Silver Fluoride Intervention to Improve Oral Health Trajectories of Young Indigenous Australians: Protocol for a Cluster Randomized Controlled Trial
  6. 302006
    “…In this setting, the study further aimed to collect data on critical predictors of user acceptance and technology adoption in education, including perceived usability, usefulness, and engagement, while also assessing training impacts. …”
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    Evaluation of a Virtual Reality Platform to Train Stress Management Skills for a Defense Workforce: Multisite, Mixed Methods Feasibility Study
  7. 302007
    “…Narrative transfer (ie, patients sending handwritten trauma accounts to therapists) was the first target for design solution development as it was deemed most critical to WET delivery. In the Design and Build phase, we identified design constraints and brainstormed solution ideas. …”
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    Improving the Usability of Written Exposure Therapy for Therapists in the Department of Veterans Affairs Telemental Health: Formative Study Using Qualitative and User-Centered Design Methods
  8. 302008
    “…Vegetation patterns represented by the Vegetation Heterogeneity Index, created ad hoc for this study, emerged as a critical factor, with 2 significant predictors related to it (P=.002 and P=.004) alongside impervious surface density with a significant predictor (P<.001). …”
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    The Relationship Between Soil-Transmitted Helminth Infections and Environmental Factors in Puerto Iguazú, Argentina: Cross-Sectional Study
  9. 302009
    “…An analysis of local cattle populations reveals that LR faces the most critical situation. This particular population has been steadily declining for a number of years, necessitating additional measures and efforts to safeguard the LR’s ancestral genetic makeup. …”
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    Genetic Variability and Conservation Challenges in Lithuanian Dairy Cattle Populations
  10. 302010
    “…SIMPLE SUMMARY: Ovum pick up and in vitro embryo production (OPU-IVEP) is a critical technique in the dairy industry that is attracting a lot of attention, especially in China’s dairy industry. …”
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    Phenotypic and Genetic Analyses of In Vitro Embryo Production Traits in Chinese Holstein Cattle
  11. 302011
    “…Background: Falls and related injuries are critical issues in several disease states, as well as aging, especially when interactions between vestibular and visual sensory inputs are involved. …”
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    The Effect of Roll Circular Vection on Roll Tilt Postural Responses and Roll Subjective Postural Horizontal of Healthy Normal Subjects
  12. 302012
    “…However, as these novel technologies gain momentum, a critical gap is the lack of comprehensive studies evaluating their efficacy and the unique experiences of patients in Africa. …”
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    Acceptability, Usefulness, and Ease of Use of an Enhanced Video Directly Observed Treatment System for Supporting Patients With Tuberculosis in Kampala, Uganda: Explanatory Qualitative Study
  13. 302013
    “…Understanding how flu antiviral use affects transmission to household (HH) members is critical to inform clinical practice. Objectives of this study were to compare the incidence of HH transmission (primary) and healthcare resource utilization (HRU, secondary) in influenza patients treated with baloxavir (BALOX) compared with oseltamivir (OSELT). …”
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    919. Household Flu Transmission and Healthcare Resource Use among Patients Treated with Baloxavir versus Oseltamivir for Influenza: An Outpatient Prospective Survey in the United States
  14. 302014
    “…Active surveillance of VREfm is essential to monitor the epidemiology of this critical pathogen in South America. DISCLOSURES: William R. …”
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    735. Vancomycin-Resistant vanB- and vanA/vanB-type Enterococcus faecium Causing Invasive Infections in Adult Patients in Chile
  15. 302015
    “…While early initiation of effective therapy is critical in serious infections, the impact of time to CZA initiation on CRE infection-related outcomes has yet to be assessed. …”
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    2779. Early Administration of Ceftazidime-Avibactam for Carbapenem-Resistant Enterobacterales Is Associated with Improved Clinical Success
  16. 302016
    “…CONCLUSION: Enforced expression of a critical number of factors offers a developmental path for unlimited expansion of neutrophil precursors, making the generation of therapeutic neutrophil transfusions a realistic and feasible countermeasure for chemotherapy or radiation-induced neutropenia. …”
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    276. A Focused Screen Identifies Essential Genes Enabling Increased Expansion in Hematopoietic Stem Cells to Generate Human Neutrophils
  17. 302017
    “…COVID-19 testing and early detection are critical but can be hindered by socioeconomic status (SES) and care access measures (CAM)-related barriers. …”
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    468. Associations of Socioeconomic Status and Care Access Measures with COVID-19 Testing in Patients with Breast Cancer
  18. 302018
    “…First, the concentrations were selected to reflect those achievable in vivo in critically ill patients using optimal dosing strategies, i.e., 16/4 mg/L for TZP, 8 mg/L for MEM, 4 mg/L for IMI. …”
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    2746. Assessment of in vitro synergy between Piperacillin-Tazobactam-Meropenem and Imipenem-Meropenem against OXA-48 Producing Klebsiella pneumoniae Using Time-Kill Assays
  19. 302019
    “…BACKGROUND: Carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (CRABC) is recognized as an urgent/critical antimicrobial resistant threat by the Centers for Disease Control and Prevention and World Health Organization. …”
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    566. Development of a Prototype Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus complex (CRABC) Assay for use on the cobas® 5800/6800/8800 System Utility Channel
  20. 302020
    “…The program resulted in significant cost and resource savings, the latter in terms of the availability of hospital rooms for other patients needing critical services. DISCLOSURES: Christina G. Rivera (O'Connor), Pharm.D, Gilead Sciences: Advisor/Consultant|Gilead Sciences: Board Member|Gilead Sciences: Grant/Research Support|Gilead Sciences: Honoraria Bijan J. …”
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    519. Early Transition to Outpatient Remdesivir Increases Patient Satisfaction while Decreasing Hospital Costs
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