“…More accurate diagnosis and management of febrile illnesses is critically needed both now and as fever aetiologies change with further reductions in malaria.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: From the 900 references initially screened, 172 articles were selected and critically assessed until 48 articles remained. The majority originated in North-America (USA: n=24, Canada: n=11). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Developing and evaluating new ways to increase consumer demand for evidence-based cessation services is critical to cost-efficiently reduce population smoking prevalence. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Thus, the development and characterization of mutant and/or knock out zebrafish are critical to help define immune cell and immune gene functions in the zebrafish model. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The protein product, TNF-α, activates the nuclear factor kappa beta (NF-κB) transcription factor, and is critical for inflammatory and apoptotic responses in cancer progression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Since complete virus particles are not found inside the cell, the processes of assembly, morphogenesis, budding and release of progeny virus particles at the plasma membrane of the infected cells are critically important for the production of infectious virions and pathogenesis of influenza viruses as well. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Educational and technical assistance for lay users and providers are critical to meet challenges related to: access to PCHRs, especially among older cohorts; workflow demands and resistance to change among providers; inadequate health and technology literacy; clarification of boundaries and responsibility for ensuring accuracy and integrity of health information across distributed data systems; and understanding confidentiality and privacy risks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Effects were not seen in eyes treated with buffer or with ODNs having the rd1 mutant sequence, a definitive control for this therapeutic approach. Importantly, critical experiments were confirmed in two laboratories by several different researchers using independent mouse colonies and ODN preparations from separate sources. …”
Enlace del recurso
Enlace del recurso

“…Abnormal mineral metabolism in chronic kidney disease plays a critical role in vascular calcification and arterial stiffness. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Distribution of ClpB proteins to different cell organelles indicates that their functioning might be critical in different cell locations. From the complementation assays, OsClpD1 appears to be more effective than OsClpB-cyt protein in rescuing the thermosensitive defect of the yeast ScΔhsp104 mutant cells.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Conducting these five trials in a period of six years provided us with invaluable insights into trial implementation, community participation, recruitment and retention, provision of care and dissemination of trial results. The critical mass of scientists trained as clinical trialists will continue to address the relentless HIV epidemic in our setting and ensure our commitment to finding a biomedical HIV prevention option for women in the future.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among the genes induced by HSF1, Bcl-2- associated athanogene 3 (BAG3) is notable for its actions in promoting cell survival through stabilization of antiapoptotic Bcl-2 proteins, appearing to have a critical role in mediating cellular protection against electrophile-induced death.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Studies were selected and critically appraised by two independent reviewers. Results Fifty four studies were included. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Detailed patterns of population genetic diversity of Atlantic salmon at a sub-continent-wide level have been evaluated, demonstrating the existence of regional genetic signatures. Critically, these appear to be independent of more commonly recognised terrestrial biogeographical and political boundaries, allowing reporting regions to be defined. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Considering their importance, the measurement of household food resources becomes critical. Because most studies use a single point of data collection to determine the types of foods that are present in the home, which can miss the change in availability within a month and when resources are not available, the primary objective of this pilot study was to examine the feasibility and value of conducting weekly in-home assessments of household food resources over the course of one month among low-income Mexicano families in Texas colonias. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: SHANK3 is a protein in the core of the postsynaptic density (PSD) and has a critical role in recruiting many key functional elements to the PSD and to the synapse, including components of α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid (AMPA), metabotropic glutamate (mGlu) and N-methyl-D-aspartic acid (NMDA) glutamate receptors, as well as cytoskeletal elements. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Studies have shown that miRNAs play a critical role in human cancer and they can influence the level of cell proliferation and apoptosis by modulating gene expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, peri-ulceral transcutaneous oxygen partial pressures of below 10 mmHg should be considered as being critical and are an indication for a prophylactic oxygen inhalation treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Pretreatment is a critical step in the conversion of lignocellulose to fermentable sugars. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Striatin-associated PP2A is critical for Mst3 dephosphorylation and inactivation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso