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  1. 302081
    “…The orbitofrontal cortex is critical to subsequent memory formation in control subjects and patients. …”
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    A functional magnetic resonance imaging study mapping the episodic memory encoding network in temporal lobe epilepsy
  2. 302082
    “…BACKGROUND: Public health surveillance and epidemiologic investigations are critical public health functions for identifying threats to the health of a community. …”
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    The epidemiology and surveillance response to pandemic influenza A (H1N1) among local health departments in the San Francisco Bay Area
  3. 302083
    “…Coinhibitory PD-1/PD-L1 (B7-H1) interactions provide critical signals for the regulation of autoreactive T-cell responses. …”
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    A Missing PD-L1/PD-1 Coinhibition Regulates Diabetes Induction by Preproinsulin-Specific CD8 T-Cells in an Epitope-Specific Manner
  4. 302084
    “…BACKGROUND: Recent findings suggest that the intake of specific nutrients during the critical period in early life influence cognitive and behavioural development profoundly. …”
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    The effects of prenatal and early postnatal tocotrienol-rich fraction supplementation on cognitive function development in male offspring rats
  5. 302085
    “…Keeping health care providers and other first-line responders informed during an emergency is critical. Better coordination between organizations disseminating alerts, advisories and other messages may improve the ability of health care providers to recall public health emergency messages, potentially impacting effective response to public health emergency messages.…”
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    Public health communications and alert fatigue
  6. 302086
    “…Health and public health professionals should educate the public about acquiring health information online and how to critically appraise it, and provide tools to navigate to the highest-quality information. …”
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    Parents Seeking Health-Related Information on the Internet: Cross-Sectional Study
  7. 302087
    “…Therefore, HIV prevention in HIV-positive MSM is a critical issue. OBJECTIVE: Condom-Him, an Internet-based intervention tailored to increase condom use among HIV-positive MSM, was developed with the aim of improving condom use, self-efficacy, and intentions to use condoms among these individuals. …”
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    An Internet-Based Intervention (Condom-Him) to Increase Condom Use Among HIV-Positive Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial
  8. 302088
    “…Case management of newborns with signs of infection, safe oxygen management and supportive care for those with respiratory complications, and care for those with significant jaundice are all critical, and are especially dependent on competent nursing care. …”
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    Born Too Soon: Care for the preterm baby
  9. 302089
    “…ABSTRACT: Pregnancy and childbirth represent a critical time period when a woman can be reached through a variety of mechanisms with interventions aimed at reducing her risk of a preterm birth and improving her health and the health of her unborn baby. …”
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    Born Too Soon: Care during pregnancy and childbirth to reduce preterm deliveries and improve health outcomes of the preterm baby
  10. 302090
    “…This finding might also be functionally important as GCDFP-15/PIP has previously been shown to bind to Aquaporin 5 (AQP5), a salivary gland water channel, critical to saliva formation that is known to be downregulated in pSS. …”
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    Gross Cystic Disease Fluid Protein-15(GCDFP-15)/Prolactin-Inducible Protein (PIP) as Functional Salivary Biomarker for Primary Sjögren’s Syndrome
  11. 302091
    “…As public discourse on a number of critical health topics continues to be influenced and sometimes shaped by discussions online from Twitter to Facebook, it would seem that greater discourse is needed about when and how public health professionals should engage in these media, and also how personal, institutional, and professional barriers to greater use of social media may be overcome.…”
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    Mind the Gap: Social Media Engagement by Public Health Researchers
  12. 302092
    por Gandhi, Gian, Lydon, Patrick
    Publicado 2014
    “…Understanding the changing face of delivery costs and cost structures for SIAs will continue to be critical to avoid funding gaps and in order to improve vaccination coverage, reduce health inequities, and achieve the ADC/E/E goals many of which have been endorsed by the World Health Assembly and are included in the Decade of Vaccines Global Vaccine Action Plan.…”
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    Updating the evidence base on the operational costs of supplementary immunization activities for current and future accelerated disease control, elimination and eradication efforts
  13. 302093
    “…BACKGROUND: In mammalians, HIF is a master regulator of hypoxia gene expression through direct binding to DNA, while its role in microRNA expression regulation, critical in the hypoxia response, is not elucidated genome wide. …”
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    Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia
  14. 302094
    “…BACKGROUND: Allograft fibrosis still remains a critical problem in transplantation, including heart transplantation. …”
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    IL-13 signaling via IL-13Rα(2) triggers TGF-β(1)-dependent allograft fibrosis
  15. 302095
    “…BACKGROUND: MicroRNAs (miRNAs) can post-transcriptionally regulate gene expression and have been shown to be critical regulators to the fine-tuning of epithelial immune responses. …”
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    Transcriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureus bacteria reveals pathogen directed microRNA expression profiles
  16. 302096
    “…The TCR complementarity-determining region 3 (CDR3) contains variable α and β loops critical for pMHC recognition. During any immune response, tuning of TCR usage through progressive clonal selection occurs. …”
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    Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile
  17. 302097
    “…Understanding how members of multidisciplinary development teams experience the UCD process might help to gain insight into factors that members with different backgrounds consider critical during the development of telecare products and services. …”
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    Experiences of Multidisciplinary Development Team Members During User-Centered Design of Telecare Products and Services: A Qualitative Study
  18. 302098
    “…Complications during hospital treatment included sepsis and organ failure according to the criteria of the American College of Chest Physicians/Society of Critical Care Medicine (ACCP/SCCM) consensus conference committee and the Sequential Organ Failure Assessment (SOFA) score. …”
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    Survival benefit of helicopter emergency medical services compared to ground emergency medical services in traumatized patients
  19. 302099
    “…NF- κB amyloid and STAT3, critical transcriptional factors regulating not only inflammation but also amyloidogenesis, were also inhibited in a concentration dependent manner by ent-Sauchinone by blocking the phosphorylation of I κB and STAT3 in cultured astrocytes and microglial BV-2 cells. …”
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    Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells
  20. 302100
    “…The ligand OX26 plays a critical role in transporting the lipoplexes across the BBB, and CTX acts as a major role in targeting brain glioma cells. …”
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    OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma
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