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302181por Wu, Zhe, Zhang, Ting, Li, Lei, Xu, Jian, Qin, Xiaodong, Zhang, Tinglin, Cui, Li, Lou, Qunfeng, Li, Ji, Chen, Jinfeng“…Finding novel and effective quantitative trait loci (QTLs) is a critical step towards understanding its genetic mechanism. …”
Publicado 2016
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302182por Chaet, Alexis V, Morshedi, Bijan, Wells, Kristen J, Barnes, Laura E, Valdez, Rupa“…BACKGROUND: As consumer health information technology (IT) becomes more thoroughly integrated into patient care, it is critical that these tools are appropriate for the diverse patient populations whom they are intended to serve. …”
Publicado 2016
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302183por Wagner, Natascha, Ouedraogo, Denis, Artavia-Mora, Luis, Bedi, Arjun, Thiombiano, Boundia Alexandre“…BACKGROUND: Retention in care and adherence to antiretroviral therapy (ART) among people living with human immunodeficiency virus (PLHIV) is a critical challenge in many African countries including Burkina Faso. …”
Publicado 2016
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302184por Mosissa, Lemi, Kebede, Abebaw, Mindaye, Tedla, Getahun, Muluwork, Tulu, Sisay, Desta, Kassu“…Tuberculosis microscopy centers have several weaknesses like overworking, insufficiently trained personnel, inconsistent reagent supplies, and poorly maintained equipments; thus, there is a critical need for investments in laboratory infrastructure, capacity building, and quality assurance schemes. …”
Publicado 2016
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302185por Tang, Dalin, del Nido, Pedro J., Yang, Chun, Zuo, Heng, Huang, Xueying, Rathod, Rahul H., Gooty, Vasu, Tang, Alexander, Wu, Zheyang, Billiar, Kristen L., Geva, Tal“…BACKGROUND: Accurate calculation of ventricular stress and strain is critical for cardiovascular investigations. Sarcomere shortening in active contraction leads to change of ventricular zero-stress configurations during the cardiac cycle. …”
Publicado 2016
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302186“…Daily field notes and meticulous oversight of collected data were critical to ensuring data quality. CONCLUSIONS: Mobile technology can support timely and accurate data collection and also help monitor data quality through the use of real-time uploads. …”
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302187“…OBJECTIVES: The aims were to perform a systematic review of the literature in order to (1) identify all measurable risk factors associated with adult hospital inpatients that potentially lead to a pharmaceutical intervention; (2) critically evaluate the quality of the identified research; and (3) further subcategorise potential risk factors, so that pharmaceutical services may be targeted to patients “at risk” by identifying potential risk factors in a patient’s electronic hospital record. …”
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302188por Kim, Jin Hyoung, Patil, Ajit Mahadev, Choi, Jin Young, Kim, Seong Bum, Uyangaa, Erdenebelig, Hossain, Ferdaus Mohd Altaf, Park, Sang-Youel, Lee, John Hwa, Eo, Seong Kug“…CONCLUSIONS: CCR5 regulates JE progression via governing timely and appropriate CNS infiltration of CD4(+)Foxp3(+) Tregs, thereby facilitating host survival. Therefore, this critical and extended role of CCR5 in JE raises possible safety concerns regarding the use of CCR5 antagonists in human immunodeficiency virus (HIV)-infected individuals who inhabit regions in which both HIV and flaviviruses, such as JEV and West Nile virus, are endemic.…”
Publicado 2016
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302189por Smit, Marije, Werner, Maureen J. M., Lansink-Hartgring, Annemieke Oude, Dieperink, Willem, Zijlstra, Jan G., van Meurs, Matijs“…BACKGROUND: Intra-abdominal hypertension (IAH) is frequently present in critically ill patients and is an independent predictor for mortality. …”
Publicado 2016
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302190por Brooks, Alexandra K., Lawson, Marcus A., Rytych, Jennifer L., Yu, Kevin C., Janda, Tiffany M., Steelman, Andrew J., McCusker, Robert H.“…Increased expression of Gal-9 may be critical for neuroinflammation-dependent induction of DO expression, either acting alone (Tdo2-v1 and Tdo2-v2) or to enhance IFNγ activity (Ido1-FL and Ido2-v1). …”
Publicado 2016
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302191por Kline, Jeffrey A., Jimenez, David, Courtney, D. Mark, Ianus, Juliana, Cao, Lynn, Lensing, Anthonie W.A., Prins, Martin H., Wells, Philip S.“…Major bleeding was defined as ≥2 g/dL drop in hemoglobin or ≥2‐unit blood transfusion, bleeding in critical area, or bleeding contributing to death. The authors examined the incidence of major bleeding in patients with low‐risk assignment by the systems of Ruiz‐Gimenez et al. …”
Publicado 2016
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302192por Sahu, Manoj Kumar, Singal, Anuradha, Menon, Ramesh, Singh, Sarvesh Pal, Mohan, Alka, Manral, Mala, Singh, Divya, Devagouru, V., Talwar, Sachin, Choudhary, Shiv Kumar“…BACKGROUND AND OBJECTIVES: Adequate nutritional supplementation in infants with cardiac malformations after surgical repair is a challenge. Critically ill infants in the early postoperative period are in a catabolic stress. …”
Publicado 2016
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302193por Katirayi, Leila, Chouraya, Caspian, Kudiabor, Kwashie, Mahdi, Mohammed Ali, Kieffer, Mary Pat, Moland, Karen Marie, Tylleskar, Thorkild“…Therefore, ensuring that ART eligible women are initiated on ART is critical for PMTCT and for mother and baby survival. …”
Publicado 2016
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302194“…Such countries should induce home-based directly observed therapy programs to reduce costs due to attending health facilities, intensify home treatment of critically-ill patients with impaired mobility, and reduce the spread of TB due to patients traveling to seek care. …”
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302195por Fyfe, Jackson J., Bartlett, Jonathan D., Hanson, Erik D., Stepto, Nigel K., Bishop, David J.“…This suggests endurance training intensity is not a critical mediator of interference to maximal strength gain during short-term concurrent training.…”
Publicado 2016
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302196“…BACKGROUND: Central vision, critical for everyday tasks such as reading and driving, is impacted by age-related changes in the eye and by diseases such as age-related macular degeneration. …”
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302197por Wibmer, Constantinos Kurt, Gorman, Jason, Anthony, Colin S., Mkhize, Nonhlanhla N., Druz, Aliaksandr, York, Talita, Schmidt, Stephen D., Labuschagne, Phillip, Louder, Mark K., Bailer, Robert T., Abdool Karim, Salim S., Mascola, John R., Williamson, Carolyn, Moore, Penny L., Kwong, Peter D., Morris, Lynn“…The cocrystal structure of CAP257-RH1 bound to RHPA gp120 revealed critical interactions with the N276 glycan, loop D, and V5, but not with aspartic acid 368, similarly to HJ16 and 179NC75. …”
Publicado 2016
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302198“…RESULTS: Demographic as well as baseline and pretreatment characteristics were comparable for the randomly selected data sets of both index groups without any indicators for critical selection biases. Treatment with OXN resulted formally in a BRP noninferior to that of TAP and showed a significantly higher primary end point response vs TAP (39.8% vs 25.6%, odds ratio: 1.93; P=0.014), due to superior analgesic effects. …”
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302199por Frost, Steven A., Alogso, Mari-Cris, Metcalfe, Lauren, Lynch, Joan M., Hunt, Leanne, Sanghavi, Ritesh, Alexandrou, Evan, Hillman, Kenneth M.“…In particular, due to more invasive procedures, mechanical ventilation, and critical illness, patients cared for in the intensive care unit (ICU) are at greater risk of HAI and associated poor outcomes. …”
Publicado 2016
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302200por Saldanha, Ian J., Schmid, Christopher H., Lau, Joseph, Dickersin, Kay, Berlin, Jesse A., Jap, Jens, Smith, Bryant T., Carini, Simona, Chan, Wiley, De Bruijn, Berry, Wallace, Byron C., Hutfless, Susan M., Sim, Ida, Murad, M. Hassan, Walsh, Sandra A., Whamond, Elizabeth J., Li, Tianjing“…BACKGROUND: Data abstraction, a critical systematic review step, is time-consuming and prone to errors. …”
Publicado 2016
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