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302421por Polanczyk, Magdalena J., Walker, Edwin, Haley, Daniel, Guerrouahen, Bella S., Akporiaye, Emmanuel T.“…BACKGROUND: The pleiotropic cytokine, transforming growth factor (TGF)-β, and CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) play a critical role in actively suppressing antitumor immune responses. …”
Publicado 2019
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302422por Ouayogodé, Mariétou H., Mainor, Alexander J., Meara, Ellen, Bynum, Julie P. W., Colla, Carrie H.“…MAIN OUTCOMES AND MEASURES: All-cause prevention quality indicator admissions, 30-day all-cause readmissions, acute care and critical access hospital admissions, evaluation and management visits in ambulatory settings, inpatient days, emergency department visits, total spending, post–acute care spending, health care contact days, and continuity of care (from Medicare claims). …”
Publicado 2019
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302423por Alimujiang, Aliya, Wiensch, Ashley, Boss, Jonathan, Fleischer, Nancy L., Mondul, Alison M., McLean, Karen, Mukherjee, Bhramar, Pearce, Celeste Leigh“…There are interventions available to influence life purpose; thus, understanding the association of life purpose with mortality is critical. OBJECTIVE: To evaluate whether an association exists between life purpose and all-cause or cause-specific mortality among older adults in the United States. …”
Publicado 2019
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302424por Masyuko, Sarah J, Cherutich, Peter K, Contesse, Marielle G, Maingi, Peter M, Wamuti, Beatrice M, Macharia, Paul M, Bukusi, David E, Otieno, Felix A, Spiegel, Hans ML, Dunbar, Matthew D, Golden, Matthew R, Richardson, Barbra A, Farquhar, Carey“…Understanding these differences and their drivers will be critical as aPS is brought to scale in order to ensure all PLHIV have access to these services.…”
Publicado 2019
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302425por Olson-Kennedy, Johanna, Chan, Yee-Ming, Garofalo, Robert, Spack, Norman, Chen, Diane, Clark, Leslie, Ehrensaft, Diane, Hidalgo, Marco, Tishelman, Amy, Rosenthal, Stephen“…CONCLUSIONS: This longitudinal, observational study is collecting critical data on the existing models of care for transgender youth that have been used in clinical settings for close to a decade, although with limited empirical research to support them. …”
Publicado 2019
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302426por Singha, Nayan Ranjan, Dutta, Arnab, Mahapatra, Manas, Roy, Joy Sankar Deb, Mitra, Madhushree, Deb, Mousumi, Chattopadhyay, Pijush Kanti“…The in situ strategic protrusion of APMPS, grafting of STR into the TerPol matrix, variation of crystallinity, thermal stabilities, surface properties, mechanical properties, swellability, adsorption capacities (ACs), and ligand-selective superadsorption have been inferred via analyses of unadsorbed and/or adsorbed STR-g-TerPol using Fourier transform infrared (FTIR), (1)H/(13)C NMR, UV–vis, thermogravimetric analysis, differential scanning calorimetry, X-ray diffraction, field emission scanning electron microscopy, energy-dispersive X-ray, dynamic light scattering, and rheological analyses and measuring the lower critical solution temperature, % gel content, pH at point of zero charge (pH(PZC)), and network parameters, such as ρ(c) and M(c). …”
Publicado 2019
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302427por Permyakov, Sergey E., Vologzhannikova, Alisa S., Nemashkalova, Ekaterina L., Kazakov, Alexei S., Denesyuk, Alexander I., Denessiouk, Konstantin, Baksheeva, Viktoriia E., Zamyatnin, Andrey A., Zernii, Evgeni Yu., Uversky, Vladimir N., Permyakov, Eugene A.“…Taken together, these data confirm the scaffolding function of several cluster-forming residues and point to their critical role in supporting physiological activity of recoverin.…”
Publicado 2019
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302428por Rafi, Syed K., Fernández-Jaén, Alberto, Álvarez, Sara, Nadeau, Owen W., Butler, Merlin G.“…Analysis of predicted atomic threading models of the mutant and the native SYTL4 proteins suggest a potential structural change induced by the R279C variant which eliminates the stabilizing Arg279-Asp60 salt bridge in the N-terminal half of the SYTL4, affecting the functionality of the protein’s critical RAB-Binding Domain. In the European (Non-Finnish) population, the allele frequency for this variant is 0.00042. …”
Publicado 2019
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302429“…BACKGROUND: Good quality information is critical for valid informed consent to trials, but current paper-based consent procedures are potentially unwieldy and can be difficult to comprehend, which may deter people from participating. …”
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302430por Schild, Stefanie, Sedlmayr, Brita, Schumacher, Ann-Kathrin, Sedlmayr, Martin, Prokosch, Hans-Ulrich, St.Pierre, Michael“…CONCLUSIONS: Anesthesiology—as an acute medical field—is particularly characterized by its high demands on decision making and action in dynamic, or time-critical situations. The integration of usability aspects is essential for everyday and emergency suitability. …”
Publicado 2019
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302431por Berntsen, Gro, Strisland, Frode, Malm-Nicolaisen, Kristian, Smaradottir, Berglind, Fensli, Rune, Røhne, Mette“…The authors then reviewed each intervention regarding the presence of critical elements, study design quality, and intervention effects. …”
Publicado 2019
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302432por Woldaregay, Ashenafi Zebene, Årsand, Eirik, Botsis, Taxiarchis, Albers, David, Mamykina, Lena, Hartvigsen, Gunnar“…After a thorough assessment and screening, 47 articles remained, which were critically analyzed. The interrater agreement was measured using a Cohen kappa test, and disagreements were resolved through discussion. …”
Publicado 2019
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302433por Sorrentino, Carlo, Yin, Zhinan, Ciummo, Stefania, Lanuti, Paola, Lu, Li-Fan, Marchisio, Marco, Bellone, Matteo, Di Carlo, Emma“…BACKGROUND: Interleukin(IL)-30/IL-27p28 production by Prostate Cancer (PC) Stem-Like Cells (SLCs) has proven, in murine models, to be critical to tumor onset and progression. In PC patients, IL-30 expression by leukocytes infiltrating PC and draining lymph nodes correlates with advanced disease grade and stage. …”
Publicado 2019
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302434por Janssens, Rosanne, Russo, Selena, van Overbeeke, Eline, Whichello, Chiara, Harding, Sarah, Kübler, Jürgen, Juhaeri, Juhaeri, Bywall, Karin Schölin, Comanescu, Alina, Hueber, Axel, Englbrecht, Matthias, Nikolenko, Nikoletta, Pravettoni, Gabriella, Simoens, Steven, Stevens, Hilde, Hermann, Richard, Levitan, Bennett, Cleemput, Irina, de Bekker-Grob, Esther, Veldwijk, Jorien, Huys, Isabelle“…As the adoption of PP heavily relies on these stakeholders, knowledge of their perceptions of PP is critical. OBJECTIVE: This study aimed to characterize stakeholders’ attitudes, needs, and concerns with respect to PP in decision making along the medical product lifecycle. …”
Publicado 2019
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302435por Yang, Hongtian, Graham, Leah C., Reagan, Alaina M., Grabowska, Weronika A., Schott, William H., Howell, Gareth R.“…BACKGROUND: Environmental factors are critical in the development of age-related cognitive decline and dementia. …”
Publicado 2019
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302436por Wollersheim, Tobias, Grunow, Julius J., Carbon, Niklas M., Haas, Kurt, Malleike, Johannes, Ramme, Sara F., Schneider, Joanna, Spies, Claudia D., Märdian, Sven, Mai, Knut, Spuler, Simone, Fielitz, Jens, Weber‐Carstens, Steffen“…BACKGROUND: Early mobilization improves physical independency of critically ill patients at hospital discharge in a general intensive care unit (ICU)‐cohort. …”
Publicado 2019
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302437“…Microglia plays a critical role in neuroinflammation after ischemic stroke by releasing diverse inflammatory cytokines. …”
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302438por Caleyachetty, Rishi, Uthman, Olalekan A., Bekele, Hana Nekatebeb, Martín-Cañavate, Rocio, Marais, Debbie, Coles, Jennifer, Steele, Briony, Uauy, Ricardo, Koniz-Booher, Peggy“…Breastfeeding within the first hour of birth is critical to newborn survival, and exclusive breastfeeding for 6 months is recognised to offer significant health benefits to mothers and their infants. …”
Publicado 2019
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302439por Tabi, Katarina, Randhawa, Abnashi Singh, Choi, Fiona, Mithani, Zamina, Albers, Friederike, Schnieder, Maren, Nikoo, Mohammadali, Vigo, Daniel, Jang, Kerry, Demlova, Regina, Krausz, Michael“…In this context, a reliable medication management tool adaptable to the patient’s needs becomes critical. As most people have a mobile phone, mobile apps offer a platform for such a personalized support tool available on the go. …”
Publicado 2019
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302440por Nguyen, Diep Thi Ngoc, Hughes, Suzanne, Egger, Sam, LaMontagne, D. Scott, Simms, Kate, Castle, Phillip E., Canfell, Karen“…These findings emphasize the critical importance of women in family outcomes and the importance of health care for women during the intrapartum and postpartum periods and throughout their child rearing years. …”
Publicado 2019
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