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  1. 302661
    “…INTRODUCTION: Assessing the impact of COVID-19 policy is critical for informing future policies. However, there are concerns about the overall strength of COVID-19 impact evaluation studies given the circumstances for evaluation and concerns about the publication environment. …”
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    Problems with Evidence Assessment in COVID-19 Health Policy Impact Evaluation: A systematic review of study design and evidence strength
  2. 302662
    “…We chose the context of cystic fibrosis (CF) care in Sweden, where coproduction between patients, their families, and health care professionals is critical in the introduction of new drugs. The first author, who is a lawyer and parent of children with CF, was a driver in the change process. …”
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    Sharing Patient-Controlled Real-World Data Through the Application of the Theory of Commons: Action Research Case Study
  3. 302663
    “…Human leukocyte antigen-G (HLA-G) has been widely acknowledged to play critical roles in fetal-maternal maintenance. However, the significance of using maternal serum sHLA-G to detect prenatal chromosomal abnormality has not been investigated. …”
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    Evaluation of Maternal Serum sHLA-G Levels for Trisomy 18 Fetuses Screening at Second Trimester
  4. 302664
    “…INTERPRETATION: People most at risk of MSFI were those in a critical economic situation before and during the pandemic. …”
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    Online Artículo Texto
    Social predictors of food insecurity during the stay-at-home order due to the COVID-19 pandemic in Peru. Results from a cross-sectional web-based survey
  5. 302665
    “…CONCLUSIONS: Rapid assessments drawing from online community insights may be a critical source of data that can be used to ensure more responsive policy action to improve patient care.…”
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    Online Artículo Texto
    Using a Twitter Chat to Rapidly Identify Barriers and Policy Solutions for Metastatic Breast Cancer Care: Qualitative Study
  6. 302666
    “…Accurate segmentation of cerebral vasculature and a quantitative assessment of its morphology is critical to various diagnostic and therapeutic purposes and is pertinent to studying brain health and disease. …”
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    Automatic segmentation, feature extraction and comparison of healthy and stroke cerebral vasculature
  7. 302667
    por Zhu, Jie, Xiao, Jiani, Wang, Min, Hu, Daixing
    Publicado 2021
    “…PURPOSE: N6-methyladenosine (m(6)A) methylation plays a critical role in diverse biological processes. However, knowledge regarding the constitution of m(6)A on tumor microenvironment (TME) and tumor-infiltrating lymphocytes (TILs) across cancer types is still lacking. …”
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    Pan-Cancer Molecular Characterization of m(6)A Regulators and Immunogenomic Perspective on the Tumor Microenvironment
  8. 302668
    “…CONCLUSION: In a scenario which is evolving very quickly, a critical factor is the availability of specific and updated regulations. …”
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    Online Artículo Texto
    Pharmacovigilance and the digital world in Italy: presentation of the results of a national survey
  9. 302669
    “…Due to the large LoA between the ECG and PVM watch, it is not advisable to use this device in clinical populations in which accurate HR measures are essential for patient safety; however, the watch maybe used in settings where less accurate HR is not critical to an individual’s safety while exercising.…”
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    Validity of the Polar Vantage M watch when measuring heart rate at different exercise intensities
  10. 302670
    “…In event-related potential (ERP) research, it is critical that these systems have precise and accurate timing. …”
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    It’s all about time: precision and accuracy of Emotiv event-marking for ERP research
  11. 302671
    “…Patient-physician interaction is recognized as a critical success factor for patient satisfaction, treatment adherence, and subsequent treatment outcomes. …”
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    Online Artículo Texto
    Deliberative and Paternalistic Interaction Styles for Conversational Agents in Digital Health: Procedure and Validation Through a Web-Based Experiment
  12. 302672
    “…Gut tissue-resident memory T cells play critical roles in mediating protective immunity and in maintaining gut homeostasis, yet few studies have investigated the effect of aging on human gut T cell immunity. …”
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    Reduced immune-regulatory molecule expression on human colonic memory CD4 T cells in older adults
  13. 302673
    “…A dose-response relationship was found between household income and depressive symptoms across previous mental health diagnosis strata, being as low as 32% less in the wealthiest than the most impoverished group (PR: 0.68, 95%CI 0.58,0.79). Other critical factors associated with a higher burden of depressive symptoms were lower education level, single, unemployed, and chronic comorbidity. …”
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    Depressive symptoms among Peruvian adult residents amidst a National Lockdown during the COVID-19 pandemic
  14. 302674
    “…We used the Joanna Briggs Institute (JBI) Meta-Analysis of Statistics Assessment and Review Instrument for critical appraisal of studies. The meta-analysis and Meta regressions were conducted using STATA 14 software. …”
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    Incidence and predictors of tuberculosis among HIV patients after initiation of antiretroviral treatment in Ethiopia: a systematic review and meta-analysis
  15. 302675
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    Cardiovascular Disease and Severe Hypoxemia Are Associated With Higher Rates of Noninvasive Respiratory Support Failure in Coronavirus Disease 2019 Pneumonia
  16. 302676
    “…For the potential use of kaempferol in clinical practice, it will be necessary to optimize the dose size and critical age of the patient so that this flavonoid may be beneficial as a preventive drug against cancer and neurological disorders.…”
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    Antioxidant vs. Prooxidant Properties of the Flavonoid, Kaempferol, in the Presence of Cu(II) Ions: A ROS-Scavenging Activity, Fenton Reaction and DNA Damage Study
  17. 302677
    “…Thus, understanding its biochemistry and enzyme activity are critical first steps for these efforts. Here, we report the crystal structure of SARS-CoV-2 Mac1 in complex with ADP-ribose and describe its ADP-ribose binding and hydrolysis activities in direct comparison to those of SARS-CoV and MERS-CoV Mac1 proteins. …”
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    The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase
  18. 302678
    “…Early and accurate diagnosis is critical in reducing the morbidity and mortality associated with malaria. …”
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    Performance of the hematology analyzer XN-31 prototype in the detection of Plasmodium infections in an endemic region of Colombia
  19. 302679
    “…CONCLUSION: OryzaGenome2.1 focuses on comparative genomic analysis of diverse wild Oryza accessions collected around the world and on the development of resources to speed up the identification of critical trait-related genes, especially from O. rufipogon. …”
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    OryzaGenome2.1: Database of Diverse Genotypes in Wild Oryza Species
  20. 302680
    por Eberle, Claudia, Stichling, Stefanie
    Publicado 2021
    “…RESULTS: From 1116 unique citations, we identified 31 eligible studies (n=15 high, n=14 moderate, n=1 weak, and n=1 critically low quality). We selected 21 SRs and MAs, 8 RCTs, 1 non-RCT, and 1 qualitative study. …”
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    Clinical Improvements by Telemedicine Interventions Managing Type 1 and Type 2 Diabetes: Systematic Meta-review
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