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  1. 302821
    “…These patients were critically ill, developed BSI in the second week of hospitalization, had longer DOT prior to positive cultures and worse outcomes. …”
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    201. Comparison of Bloodstream Infections Between Hospitalized Patients with and without COVID-19 Infection During the First Wave of the COVID-19 Pandemic in a Community Hospital in South Bronx: An Observational Study
  2. 302822
    “…Familiarity with early imaging signs is critical to prevent associated morbidity /mortality. …”
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    326. Radiologic Findings of COVID-19 Associated Mucormycosis (CAM) from India
  3. 302823
    “…BACKGROUND: Most individuals diagnosed with mild to moderate COVID-19 are no longer infectious after day 10 of symptom onset and those with severe or critical illness from COVID are typically not infection after day 20 day of symptom onset. …”
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    278. Immunocompromised Patients with Prolonged Viral Shedding of SARS-COV-2
  4. 302824
    “…[Image: see text] CONCLUSION: CFDC has potential for treating respiratory tract infections caused by Burkholderia spp. In critically ill patients, the recommended dosing regimen achieves 100% of fT >MIC of ≤ 4 ug/mL(3)).3) N. …”
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    1058. In Vitro and In Vivo Antibacterial Activity of Cefiderocol against Burkholderia spp
  5. 302825
    “…More cases were receiving chemotherapy (10.2% versus 0.8%, p< 0.001), were on TPN (17.3% versus 8.3%, p=0.015) and had been admitted to critical care (73.2% versus 60.7%, p=0.017). Cases were also more likely to have peripherally inserted central venous catheters (37% versus 25%, p=0.017) and have the insertion done in the radiology department under radiological guidance (69.3% versus 55.2%, p=0.011). …”
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    775. Risk Factors for Healthcare Associated Central Line-Associated Bloodstream Infection (CLABSI) to Identify Novel Infection Prevention Areas - A Case-Control Study
  6. 302826
    “…BACKGROUND: Until now, studies have been focused on patient-centered risk factors, while SARS-CoV-2 aggressiveness has been established as causing 20% of severe and critical patients. However, there are still many unanswered questions concerning the clinical aggressiveness behavior of SARS-CoV-2. …”
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    436. U-shaped-aggressiveness of SARS-CoV-2: Period Between Initial Symptoms and Clinical Progression to COVID-19 Suspicion. A Population-Based Cohort Study
  7. 302827
    “…Healthcare workers (HCW) are a critical workforce during the COVID-19 pandemic but are themselves often at increased risk of infection. …”
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    375. High Laboratory-confirmed SARS-CoV-2 Attack Rate in Lima Health Care Personnel During August 2020-March 2021 Suggests Role for Improved Infection Control
  8. 302828
    “…Despite the reduction in pharmacy personnel due to the pandemic, the ASP pharmacy lead took on a novel and critical stewardship role throughout the pandemic exemplified by their involvement in novel treatment allocation for COVID patients. …”
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    106. Pandemic Pinch: The Impact of COVID Response on Antimicrobial Stewardship Program (ASP) Resource Allocation
  9. 302829
    “…However, there is still an increased risk of toxicity to the surrounding critical structures that lead to poor treatment outcomes. …”
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    Therapeutic Efficacy of Variable Biological Effectiveness of Proton Therapy in U-CH2 and MUG-Chor1 Human Chordoma Cell Death
  10. 302830
    “…Therefore, it is important to adopt programs to encourage the desire for more children, implement policies in an attempt to increase the total fertility rate in Ethiopia ought to critically consider these factors. Moreover, continuous education and knowledge on reproductive health will help for better fertility behaviour for the women.…”
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    Determinants of desire for more children among women in Ethiopia
  11. 302831
    “…These findings extend previous research, which demonstrated that engagement with Happify as recommended was associated with improved well-being among physically healthy users and in those with chronic conditions, to a new population for whom mental health is especially critical: those at risk of developing CVD.…”
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    The Effects of a Digital Mental Health Intervention in Adults With Cardiovascular Disease Risk Factors: Analysis of Real-World User Data
  12. 302832
    “…Mobile technology is pervasive and presents an opportunity to reach young people with critical sexual reproductive health and family planning messages. …”
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    Formative Study of Mobile Phone Use for Family Planning Among Young People in Sierra Leone: Global Systematic Survey
  13. 302833
    “…A better understanding of the characteristics of users and nonusers is critical for understanding which groups remain excluded from using such tools. …”
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    Determinants of Use of the Care Information Exchange Portal: Cross-sectional Study
  14. 302834
    “…BACKGROUND: Early learning and childcare centers (ELCCs) can offer young children critical opportunities for quality outdoor play. There are multiple actual and perceived barriers to outdoor play at ELCCs, ranging from safety fears and lack of familiarity with supporting play outdoors to challenges around diverse perspectives on outdoor play among early childhood educators (ECEs), administrators, licensing officers, and parents. …”
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    A Web-Based Risk-Reframing Intervention to Influence Early Childhood Educators’ Attitudes and Supportive Behaviors Toward Outdoor Play: Protocol for the OutsidePlay Study Randomized Controlled Trial
  15. 302835
    “…Sufficient donor myeloid chimerism (DMC) is critical for the success of HSCT; here, we evaluated immune cells among high (H) DMC (DMC≥20%) and low (L) DMC (DMC<20%) groups along with engrafted and rejected groups. …”
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    Early Myeloid Derived Suppressor Cells (eMDSCs) Are Associated With High Donor Myeloid Chimerism Following Haploidentical HSCT for Sickle Cell Disease
  16. 302836
    “…In particular, there is evidence supporting a critical role of astroglial activation and astrocytosis in Alzheimer’s disease. …”
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    Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer’s disease
  17. 302837
    “…METHODS: We applied PRISMA guidelines to conduct a systematic review and meta-analysis to retrieve, quantitatively pool and critically evaluate the association between retirement and both incident and prevalent depression and to understand better the potential role of individual and contextual-level determinants. …”
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    Does retirement trigger depressive symptoms? A systematic review and meta-analysis
  18. 302838
    “…SIGNIFICANCE: Membrane proteins are involved in various physiological and biochemical functions critical for cellular function. It is also dynamic in nature, where many proteins are changed during in response to environmental stress. …”
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    Membrane proteomic analysis identifies the polarity protein PARD3 as a novel antiviral protein against PEDV infection
  19. 302839
    “…Safe and equitable full-in-person school instruction is a critical factor in the continued educational gains of children and for their general well-being. …”
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    Phased Return of Students to 77 Transitional Kindergarten-8th Grade Schools With Cohesive Mitigation Strategies Serving as Protective Factors Against the Increase of COVID-19 Cases in Marin County: September 2020-January 2021
  20. 302840
    “…Larger defects (=10 mm) remain a critical point of interest with predictive clinical value for OLT outcomes.…”
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    Osteochondral Lesions of the Talus – A Biomechanical Explanation for Larger OLT Shoulder Lesions Leading to Increased Patient Risk
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