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  1. 302941
    “…To adequately harness this opportunity, it is critical that the design and development of digital mental health technologies be informed by the needs and preferences of end users. …”
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    Ownership, Use of, and Interest in Digital Mental Health Technologies Among Clinicians and Young People Across a Spectrum of Clinical Care Needs: Cross-sectional Survey
  2. 302942
    “…SIMPLE SUMMARY: In this study, we investigated and compared six different Bayesian network algorithms from three different categories to identify hub genes critical to gene expression networks activated in response to progesterone in the bovine uterus. …”
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    Constraint-Based, Score-Based and Hybrid Algorithms to Construct Bayesian Gene Networks in the Bovine Transcriptome
  3. 302943
    “…Memory B cells, however, are critical in sustaining long-term protection and therefore may be an important factor when assessing pertussis immunity after vaccination. …”
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    Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries
  4. 302944
    “…Understanding the types, effectiveness, and flaws of current HBC mitigation measures is critical to develop effective strategies to alleviate HBC. …”
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    Mitigation Strategies for Human–Tibetan Brown Bear (Ursus arctos pruinosus) Conflicts in the Hinterland of the Qinghai-Tibetan Plateau
  5. 302945
    “…Selective inhibition of TYK2 over other JAK isoforms is critical to achieve a favorable therapeutic index in the development of TYK2 inhibitors. …”
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    Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways
  6. 302946
    “…BACKGROUND: Food insecurity is a critical public health problem in the United States that has been associated with poor diet quality. …”
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    Online Artículo Texto
    Food Insecurity and Less Frequent Cooking Dinner at Home Are Associated with Lower Diet Quality in a National Sample of Low-Income Adults in the United States during the Initial Months of the Coronavirus Disease 2019 Pandemic
  7. 302947
    “…BACKGROUND: Acute hypoxic respiratory failure (AHRF) is a hallmark of severe COVID-19 pneumonia and often requires supplementary oxygen therapy. Critically ill COVID-19 patients may require invasive mechanical ventilation, which carries significant morbidity and mortality. …”
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    Dynamic blood oxygen indices in mechanically ventilated COVID-19 patients with acute hypoxic respiratory failure: A cohort study
  8. 302948
    “…To help laboratories in low-resource countries conduct folate measurements, the CDC developed a folate MBA kit containing critical reagents: calibrator, microorganism, quality control (QC), and reagent stock solutions to prepare culture medium. …”
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    Robustness of the CDC Folate Microbiologic Assay Kit During Simulated Delayed Shipping
  9. 302949
    “…To help laboratories in low-resource countries conduct folate measurements, the CDC developed a folate MBA kit containing critical reagents: calibrator, microorganism, quality control (QC), and reagent stock solutions to prepare culture medium. …”
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    Robustness of the CDC Folate Microbiologic Assay Kit During Simulated Delayed Shipping
  10. 302950
    “…OBJECTIVES: Iodine is an essential micronutrient that plays a critical role in child growth and development. This study aimed to examine median urinary iodine concentrations (mUIC) by country and key health and sociodemographic factors. …”
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    Median Urinary Iodine Concentration in School-Age Children Does Not Consistently Vary by Inflammation or Sociodemographic Factors: Multi-Country Analysis From BRINDA
  11. 302951
    “…Weight loss improves glycemic control and scalable weight management programs tailored for those living with diabetes are critically needed. The objective of this trial was to test the efficacy of a scalable and widely available diabetes-tailored weight management program (WW, formerly Weight Watchers) on glycemic control, weight, hunger, and quality of life (QOL) in adults with T2D and overweight/obesity. …”
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    A Scalable, Weight Management Program Tailored for Adults with Type 2 Diabetes: Effects on Glycemic Control, Weight, Hunger, and Quality of Life
  12. 302952
    “…BACKGROUND: Even though practicing levels of safe cord care and skin-to-skin contact among post-partum women are critical to reducing neonatal deaths, limited data revealed the low practice. …”
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    Practicing Level and Determinants of Safe Cord Care and Skin-To-Skin Contact Among Post-partum Women in Public Hospitals of Eastern Ethiopia
  13. 302953
    “…In addition, the respondents’ perception of the existence of the disease (OR: 1.45; 95% CI: 0.99,2.18; p > 0.05), the need for a COVID-19 vaccine (OR: 16; 95% CI: 11.63,22.10; p < 0.001), the willingness to pay (OR: 1.68; 95% CI: 1.39,2.01; p < 0.001) and the rating of the government handling of the pandemic (OR: 2.25; 95% CI: 1.57,3.23; p < 0.001) were critical to the acceptance of the COVID-19 vaccine. …”
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    A national survey of COVID-19 vaccine acceptance in Nigeria
  14. 302954
    “…BACKGROUND: The Discovery Critical Care Research Network Program for Resilience and Emergency Preparedness (Discovery PREP) partnered with a third-party technology vendor to design and implement an electronic data capture tool that addressed multisite data collection challenges during public health emergencies (PHE) in the United States. …”
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    An Electronic Data Capture Tool for Data Collection During Public Health Emergencies: Development and Usability Study
  15. 302955
    “…IMPORTANCE Estimation of community-level antibody responses to SARS-CoV-2 from infection or vaccination is critical to inform public health responses. Traditional studies of antibodies rely on collection of blood via venipuncture, an invasive procedure not amenable to pandemic-related social-distancing measures. …”
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    Development and Implementation of Dried Blood Spot-Based COVID-19 Serological Assays for Epidemiologic Studies
  16. 302956
    “…Preventive treatment could effectively protect individuals at a high risk of developing active disease from LTBI, and is regarded as a critical component of End TB Strategies. Biomarkers which could accurately identify high-risk population and predict the risk of disease development are urgently needed for developing local guidelines of LTBI management and precise intervention. …”
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    The Association between Circulating microRNAs and the Risk of Active Disease Development from Latent Tuberculosis Infection: a Nested Case-Control Study
  17. 302957
    “…The effective recognition of high-risk subjects is critical for primary prevention in the general population. …”
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    Prognostic Value of Arm Circumference for Cardiac Damage and Major Adverse Cardiovascular Events: A Friend or a Foe? A 2-Year Follow-Up in the Northern Shanghai Study
  18. 302958
    “…A content analysis of the qualitative data collected in the interviews was conducted iteratively, ensuring that no critical information was overlooked. RESULTS: The International Physical Activity Questionnaire–Short Form found that all participants (n=4) were moderately active; however, half of them did not reach the recommended levels in the guidelines. …”
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    Breast Cancer Physical Activity Mobile Intervention: Early Findings From a User Experience and Acceptability Mixed Methods Study
  19. 302959
    “…As such, the accurate prediction of N2 stage prior to surgery has become increasingly critical. But diagnostic biomarkers predicting N2 metastases are deficient, which are urgently needed. …”
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    Re-evaluating the need for mediastinal lymph node dissection and exploring lncRNAs as biomarkers of N2 metastasis in T1 lung adenocarcinoma
  20. 302960
    por WU, Qiong, SUI, Xintong, TIAN, Ruijun
    Publicado 2021
    “…With the increased demand for large cohort proteomic analysis in the biomedical research field, high-throughput proteomic analysis has become a critical issue that needs to be urgently addressed. …”
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    高通量蛋白质组学分析研究进展
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