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  1. 303041
  2. 303042
  3. 303043
    “…This is a form of cognitive flexibility and is critical to the extinction of habits and the learning of new responses. …”
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  4. 303044
  5. 303045
    “…Nonthyroidal illness syndrome (NTIS) is generally considered an adaptative response to reduced energy that is secondary to critical illness, including COVID-19. COVID-19 has been associated with profound changes in the cell energy metabolism, especially in the cells of the immune system, with a central role played by the mitochondria, considered the power units of every cell. …”
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  6. 303046
    “…Notably, the G2 residue, which has been reported to be essential for most Nef functions, was found to be critical in the regulation of innate immune activation by Nef, suggesting that compromising myristoylation or membrane attachment of Nef may be a good strategy for the inhibition of HIV infection.…”
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  7. 303047
    “…BACKGROUND: Although medical decision-making may be thought of as a task involving health professionals, many decisions, including critical health–related decisions are made by laypersons alone. …”
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  8. 303048
    “…METHODS: The Tbx4/5 genes of P. argenteus were first cloned, and the small RNA transcriptomes were sequenced by high-throughput sequencing during the critical period of the fin development at days 1, 7, and 13 of hatching. …”
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  9. 303049
    “…CONCLUSIONS: Favorable clinician perceptions of telehealth are critical for sustained use. Clinicians initially approached telehealth at varied stages of acceptance and comfort. …”
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  10. 303050
    por Albashaireh, Arwa, Henske, Joseph
    Publicado 2022
    “…When the patient does not disclose cannabis use voluntarily, taking a thorough social history is critical to making the correct diagnosis. Reference: 1. …”
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  11. 303051
    por Krützfeldt, Jan, Fahrner, Alexandra
    Publicado 2022
    “…RNA-seq of regenerating muscle annotated a critical role for miR-501 in the organisation of muscle filaments. …”
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  12. 303052
    “…Based on our findings, we recommend obtaining brain MRI in all patients diagnosed with GHD to identify critical anatomical abnormalities, like PSIS, that require long-term close monitoring of pituitary function. …”
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  13. 303053
    “…The hypothesis was tested that altered RBFOX2 gene dosage impacts the developing penis transcriptome via mRNA splicing, specifically the mesenchymal to epithelial transition critical for penile urethra formation, resulting in hypospadias.Searches, in publically available and local clinical databases, centered on hypospadias occurance with gene CNV: identified the RBFOX2 locus as a gene dosage sensitve region. …”
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  14. 303054
    “…CONCLUSION: This case illustrates the critical importance of heel-stick newborn screening for CAH to prevent a life-threatening salt-wasting crisis as female patients with classical CAH can present with a phenotypic complete lack of virilization that could be misleading and fatal if not recognized. …”
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  15. 303055
    “…Few studies have suggested PFOS may cause endocrine-disrupting effects, therefore it is critical to explore the effects of PFOS on breast cancer cells. …”
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  16. 303056
    por Caputi, Rafael, Ayala, Alejandro
    Publicado 2022
    “…Laboratories use a direct analog enzyme immunoassay to calculate the free testosterone however its calibration and specificity has been debatable, and it is still unclear how biotin can affect it. It is critical that laboratorians and clinicians are aware of this biotin interference so that misdiagnosis and inappropriate treatment can be prevented. …”
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  17. 303057
    por Gupta, Nidhi
    Publicado 2022
    “…CONCLUSIONS: While it would be irrational to suggest complete avoidance of all WMDs, moderation, balance, and real-life engagement together with strategies aimed at disrupting the dopamine habit loop will be critical components of any intervention plan. Educating patients about the neuroscience of WMD addiction and empowering them with tips to curb WMD use might impact their behavior substantially. …”
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  18. 303058
    “… : Aldosterone plays a critical role in blood pressure regulation via the renin-angiotensin-aldosterone system. …”
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  19. 303059
    por Mannino, Federica, Doc, Post
    Publicado 2022
    “…Ellagic acid, a natural polyphenolic compound derived from pomegranate, could modulate cell function via specific estrogen receptor b; activation of ERb plays a critical role in bone remodeling suppressing osteoclast differentiation and function, promoting osteoblast proliferation through the Wnt/b-catenin pathway, increasing osteoprotegerin levels. …”
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  20. 303060
    “…BACKGROUND: The identification of parathyroid tumor(s) in patients with persistent/recurrent primary hyperparathyroidism (PHPT) is critical for a successful re-operative surgery. We describe our experience with invasive studies for parathyroid tumor localization and provide follow-up data regarding our experience with selective arterial hypocalcemic stimulation with central venous sampling (SAHSCVS). …”
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