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  1. 303081
    “…BACKGROUND: Delirium prevalence is high in critical care settings. We examined the incidence, risk factors, and outcome of delirium in a medical intensive care unit (MICU) with a particular focus on liver diseases. …”
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    Liver diseases as a novel risk factor for delirium in the ICU–Delirium and hepatic encephalopathy are two distinct entities
  2. 303082
    por Harrell Shreckengost, Constance S., Foianini, Jorge Esteban, Moron Encinas, Karen Milenka, Tola Guarachi, Hugo, Abril, Katrina, Amin, Dina, Berkowitz, David, Castater, Christine Aisha, Douglas, J. Miller, Grant, April A., Khullar, Onkar Vohra, Lane, Andrea Nichole, Lin, Alice, Niroula, Abesh, Nizam, Azhar, Rashied, Ammar, Reitz, Alexandra W., Roser, Steven M., Spychalski, Julia, Arap, Sérgio Samir, Bento, Ricardo Ferreira, Ciaralo, Pedro Prosperi Desenzi, Imamura, Rui, Kowalski, Luiz Paulo, Mahmoud, Ali, Mariani, Alessandro Wasum, Menegozzo, Carlos Augusto Metidieri, Minamoto, Hélio, Montenegro, Fábio Luiz M., Pêgo-Fernandes, Paulo Manoel, Santos, Jones, Utiyama, Edivaldo Massozo, Sreedharan, Jithin K., Kalchiem-Dekel, Or, Nguyen, Jonathan, Dhamsania, Rohan K., Allen, Kerianne, Modzik, Adrian, Pathak, Vikas, White, Cheryl, Blas, Juan, Talal El-Abur, Issa, Tirado, Gabriel, Yánez Benítez, Carlos, Weiser, Thomas G., Barry, Mark, Boeck, Marissa, Farrell, Michael, Greenberg, Anya, Miller, Phoebe, Park, Paul, Camazine, Maraya, Dillon, Deidre, Smith, Randi N.
    Publicado 2022
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    Outcomes of Early Versus Late Tracheostomy in Patients With COVID-19: A Multinational Cohort Study
  3. 303083
    “…A metabolomic cluster indicative of a high ketogenic profile defines non-critical hospitalized patients with low FT3 levels.…”
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    Free triiodothyronine levels and age influences the metabolic profile and COVID-19 severity parameters in euthyroid and levothyroxine-treated patients
  4. 303084
    “…Thus, endotoxic hypertension begins through a central mechanism and further suggests that hypotension may play a critical role in developing fatal hypotension, representing the second stage of septic shock. …”
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    Cardiovascular Effect of Dorsal Periaqueductal Gray During Lipopolysaccharide-induced Hypotension
  5. 303085
    “…BACKGROUND: Considering that a high meat intake is directly associated with obesity, it is critical to address the relationship between consuming different types of meat with inflammation and metabolism in overweight and obese cohorts. …”
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    Red, white, and processed meat consumption related to inflammatory and metabolic biomarkers among overweight and obese women
  6. 303086
    “…AUTHORS' CONCLUSIONS: This report illustrates the critical value of evaluating and publishing evidence from disability inclusive TPD interventions in LMICs, including any that are ongoing, or are components of highly resource intensive large‐scale education sector programs.…”
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    Teacher professional development for disability inclusion in low‐ and middle‐income Asia‐Pacific countries: An evidence and gap map
  7. 303087
    “…The t-test was used to analyze the normally distributed data, and the Wilcoxon rank-sum test was used for abnormally distributed data. The best critical value of predictors of AF was calculated using receiver operating characteristic (ROC) curve analysis. …”
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    Morphological changes in the orifices of the left atrial appendage and left atrium in patients with atrial fibrillation
  8. 303088
    “…BACKGROUND: Optimum dietary intake and adequate nutritional knowledge have been recognized as the key factors that play a critical role in improving the athlete's health and nutrition status. …”
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    Association of nutrition knowledge, practice, supplement use, and nutrient intake with strength performance among Taekwondo players in Nepal
  9. 303089
    “…The study prospectively recruited 125 consecutive patients admitted to a coronary critical unit due to ADHF. Patients with and without AKI were compared in terms of soluble thrombomodulin (sTM), angiopoietin (Ang)-1 and −2 plasma levels as well as baseline characteristics. …”
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    Plasma thrombomodulin levels are associated with acute kidney injury in patients with acute heart failure
  10. 303090
    “…Selected cohort studies featured high-risk patients with advanced kidney disease and critical illness. METHODS: This review was designed to conform to the Preferred Reporting Items in Systematic Reviews and Meta-Analysis (PRISMA) guidelines. …”
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    Risk of acute kidney injury after contrast-enhanced computerized tomography: a systematic review and meta-analysis of 21 propensity score–matched cohort studies
  11. 303091
    “…This identified the SWI/SNF complex protein BRG1 (SMARCA4) as a critical ER: MDC1 partner. BRG1 was required for ILC cell growth, and BRG1 knockdown specifically suppressed ER regulation of MDC1-dependent ER target genes. …”
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    OR07-2 Endocrine Response And Resistance Is Driven By Novel Transcriptional Co-Regulator Activity In Invasive Lobular Carcinoma Of The Breast
  12. 303092
    “…Accumulated evidence has declared the minichromosome maintenance protein complex (MCM) gene family plays a critical role in modulating the cell cycle and DNA replication stress. …”
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    MCM4 is a novel prognostic biomarker and promotes cancer cell growth in glioma
  13. 303093
    “…The broad expression of C5aRs on multiple cell types critical for BP pathogenesis call for clinical studies targeting this axis in BP and other complement-mediated AIBDs.…”
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    Differential expression of C5aR1 and C5aR2 in innate and adaptive immune cells located in early skin lesions of bullous pemphigoid patients
  14. 303094
    “…Generally, these disorders can progress to irreversible pulmonary fibrosis and are an important cause of morbidity and mortality. It is critical to make a prompt and accurate diagnosis of the underlying causes so that patients can be managed appropriately. …”
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    Role of High-Resolution CT Thorax in Diagnosing Interstitial Lung Disease and Its Association With Smoking and Connective Tissue Disorder
  15. 303095
    “…The findings from our study will hopefully contribute to addressing the critical gap in universal provision and accessibility of mental health and emotional well-being support for people with epilepsy. …”
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    A Conversational, Virtual, Avatar-Led Cognitive Behavioral Therapy App Intervention for Improving the Quality of Life and Mental Health of People With Epilepsy: Protocol for a Randomized Controlled Trial
  16. 303096
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    Age and Comorbidities Predict COVID-19 Outcome, Regardless of Innate Immune Response Severity: A Single Institutional Cohort Study
  17. 303097
    “…Walking is also becoming a critical issue for health promotion in urban environments as it is the most often used form of active mobility and helps to replace carbon dioxide emissions from motorized forms of transport. …”
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    Analyzing Person-Place Interactions During Walking Episodes: Innovative Ambulatory Assessment Approach of Walking-Triggered e-Diaries
  18. 303098
    “…CONCLUSIONS: Our single‐cell‐based results suggested that endothelial cells may play critical roles in sarcopenia development through interferon‐GBP signalling pathways, highlighting new therapeutic directions to slow down or even reverse age‐related sarcopenia.…”
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    Single‐cell RNA‐seq reveals interferon‐induced guanylate‐binding proteins are linked with sarcopenia
  19. 303099
    “…The concept of trade-offs between technology usefulness and acceptability is critical to consider, as older adults have a hierarchy of concerns. …”
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    Evidence and User Considerations of Home Health Monitoring for Older Adults: Scoping Review
  20. 303100
    “…Secondary outcomes were measures of severity of illness including inpatient hospitalization, critical care admission, hospital lengths of stay and mortality. …”
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    Monocyte distribution width as a pragmatic screen for SARS-CoV-2 or influenza infection
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