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  1. 303201
    por Chen, Shao-Tian, Yang, Nan
    Publicado 2023
    “…Recent studies have revealed the critical effects of the ceRNA network and ferroptosis on patients with asthma. …”
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    Constructing ferroptosis-related competing endogenous RNA networks and exploring potential biomarkers correlated with immune infiltration cells in asthma using combinative bioinformatics strategy
  2. 303202
    “…CONCLUSIONS: This study provides a baseline for costs associated with implementation of an individually tailored parenting program. Results provide critical information for decision makers and a model for future economic analysis and can be used to inform optimization thresholds for implementation and, when necessary, benchmarks for program adaptation to promote scale-up. …”
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    A budget impact analysis of cost to implement a whole child health focused, family-based intervention in primary care for children with elevated BMI
  3. 303203
    “…It is known that some antibody responses may play a critical role in preventing viral infection and alleviating disease; however, the characteristics and functions of particular antibody responses in persons with previous infections are not fully understood. …”
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    Linear epitopes on the capsid protein of norovirus commonly elicit high antibody response among past-infected individuals
  4. 303204
    “…BACKGROUND: In midwifery education, the clinical learning experience (CLE) is a critical component to gaining competency and should comprise greater than 50% of a student’s education. …”
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    The impact of clinical placement site, community clinic versus tertiary hospital, on midwifery students’ clinical learning experience in Sierra Leone: a cohort study
  5. 303205
    “…In regulatory guidelines, the use of non-concurrent control data was considered critical but was deemed acceptable for rare diseases in 12/37 guidelines or was accepted in specific indications (12/37). …”
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    On the use of non-concurrent controls in platform trials: a scoping review
  6. 303206
    “…BACKGROUND: Keystone taxa are drivers of microbiome structure and functioning, which may play critical roles in microbiome-level responses to recalcitrant pollution and are a key to bioremediation. …”
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    Characterization of two keystone taxa, sulfur-oxidizing, and nitrate-reducing bacteria, by tracking their role transitions in the benzo[a]pyrene degradative microbiome
  7. 303207
    “…Choroidal vasculopathy has gradually been recognized as a critical trigger of myopic pathology. However, the precise mechanism controlling choroidal vasculopathy remains unclear. …”
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    Targeting choroidal vasculopathy via up-regulation of tRNA-derived fragment tRF-22 expression for controlling progression of myopia
  8. 303208
    “…Intriguingly, transplantation of the fecal microbiota from healthy adolescent volunteers to the chronic restraint stress (CRS)-induced adolescent depressed mice significantly ameliorated mouse depressive behaviors, in which the Roseburia exerted critical roles, since its effective colonization in the mouse colon resulted in remarkably increased 5-HT level and reciprocally decreased kynurenine (Kyn) toxic metabolites quinolinic acid (Quin) and 3-hydroxykynurenine (3-HK) levels in both the mouse brain and colon. …”
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    Microbiome and tryptophan metabolomics analysis in adolescent depression: roles of the gut microbiota in the regulation of tryptophan-derived neurotransmitters and behaviors in human and mice
  9. 303209
    “…National malaria programmes and their funding partners should work to increase the number of ITNs available to those vulnerable to malaria, while at the same time working to extend the useful life of these critical commodities. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12936-023-04609-z.…”
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    How many mosquito nets are needed to maintain universal coverage: an update
  10. 303210
    “…Recent progress in tumour microenvironment research has led to identification that extracellular matrix (ECM) remodelling and increased stiffness act as critical contributing role in tumour carcinogenesis. …”
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    Extracellular matrix remodelling and stiffening contributes to tumorigenesis of salivary carcinoma ex pleomorphic adenoma——A study based on patient-derived organoids
  11. 303211
    “…While extracellular matrix-integrin interactions play critical roles in regulating the balance between vascular stability and remodeling, it remains to be established whether manipulation of integrin function weakens or strengthens vascular integrity. …”
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    β1 integrin is essential for blood–brain barrier integrity under stable and vascular remodelling conditions; effects differ with age
  12. 303212
    “…Improved early hemorrhage control strategies seem critical for better outcome.…”
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    Management and outcomes of firearm-related vascular injuries
  13. 303213
    por Angelopoulos, V., Zhang, X.-J., Artemyev, A. V., Mourenas, D., Tsai, E., Wilkins, C., Runov, A., Liu, J., Turner, D. L., Li, W., Khurana, K., Wirz, R. E., Sergeev, V. A., Meng, X., Wu, J., Hartinger, M. D., Raita, T., Shen, Y., An, X., Shi, X., Bashir, M. F., Shen, X., Gan, L., Qin, M., Capannolo, L., Ma, Q., Russell, C. L., Masongsong, E. V., Caron, R., He, I., Iglesias, L., Jha, S., King, J., Kumar, S., Le, K., Mao, J., McDermott, A., Nguyen, K., Norris, A., Palla, A., Roosnovo, A., Tam, J., Xie, E., Yap, R. C., Ye, S., Young, C., Adair, L. A., Shaffer, C., Chung, M., Cruce, P., Lawson, M., Leneman, D., Allen, M., Anderson, M., Arreola-Zamora, M., Artinger, J., Asher, J., Branchevsky, D., Cliffe, M., Colton, K., Costello, C., Depe, D., Domae, B. W., Eldin, S., Fitzgibbon, L., Flemming, A., Frederick, D. M., Gilbert, A., Hesford, B., Krieger, R., Lian, K., McKinney, E., Miller, J. P., Pedersen, C., Qu, Z., Rozario, R., Rubly, M., Seaton, R., Subramanian, A., Sundin, S. R., Tan, A., Thomlinson, D., Turner, W., Wing, G., Wong, C., Zarifian, A.
    Publicado 2023
    “…These results confirm the critical role of EMIC waves in driving relativistic electron losses. …”
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    Energetic Electron Precipitation Driven by Electromagnetic Ion Cyclotron Waves from ELFIN’s Low Altitude Perspective
  14. 303214
    “…Risk of bias was assessed using the Joanna Briggs Institute Critical appraisal checklists, appropriate to the study design. …”
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    Failure to follow up abnormal test results associated with cervical cancer in primary and ambulatory care: a systematic review
  15. 303215
    “…CONCLUSIONS: To maximize uptake of RDA, regular education and sensitization campaigns in collaboration with village leaders on the purpose and rationale of RDA will be critical. To alleviate safety concerns and increase participant safety, a rigorous pharmacovigilance program will be important. …”
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    Assessing the acceptability and feasibility of reactive drug administration for malaria elimination in a Plasmodium vivax predominant setting: a qualitative study in two provinces in Thailand
  16. 303216
    “…CONCLUSIONS: TGF-β1 is a critical mediator of crosstalk between stromal fibroblasts and bladder cancer cells. …”
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    TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
  17. 303217
    “…The retrotransposon, Paternal Expressed Gene 10 (PEG10) harbours critical placental functions pertaining to placental trophoblast cells. …”
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    Paternal Expressed Gene 10 (PEG10) is decreased in early-onset preeclampsia
  18. 303218
    “…Continued monitoring, including molecular surveillance, is critical for decision-making on effective treatment policy in Burkina Faso.…”
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    Plasmodium falciparum drug resistance-associated mutations in isolates from children living in endemic areas of Burkina Faso
  19. 303219
    “…BACKGROUND: Substantial studies have demonstrated that oxidative stress placenta and endothelial injury are considered to inextricably critical events in the pathogenesis of preeclampsia (PE). …”
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    Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis in preeclampsia
  20. 303220
    “…In Cambodia, approximately 43%-65% of men with HIV and 3%-5% of women with HIV smoke cigarettes. Thus, there is a critical need for cost-effective smoking cessation interventions for Cambodian people with HIV. …”
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    Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People With HIV (Project EndIT): Protocol for a Randomized Controlled Trial
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