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  1. 303361
    “…BACKGROUND: Persistent infection with high-risk human papillomavirus (hrHPV) is a critical step in cervical carcinogenesis. We report on type-specific hrHPV persistence, clearance and incidence among screen-positive Rwandan women living with HIV (WLWH). …”
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    Type-specific persistence, clearance and incidence of high-risk HPV among screen-positive Rwandan women living with HIV
  2. 303362
    “…BACKGROUND: Toll-like receptor 5 (TLR5)-mediated pathways play critical roles in regulating the hepatic immune response and show hepatoprotective effects in mouse models of hepatic diseases. …”
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    Toll-like receptor 5-mediated signaling enhances liver regeneration in mice
  3. 303363
    por Permuth, Jennifer B., Dezsi, Kaleena B., Vyas, Shraddha, Ali, Karla N., Basinski, Toni L., Utuama, Ovie A., Denbo, Jason W., Klapman, Jason, Dam, Aamir, Carballido, Estrella, Kim, Dae Won, Pimiento, Jose M., Powers, Benjamin D., Otto, Amy K., Choi, Jung W., Chen, Dung-Tsa, Teer, Jamie K., Beato, Francisca, Ward, Alina, Cortizas, Elena M., Whisner, Suzanne Y., Williams, Iverson E., Riner, Andrea N., Tardif, Kenneth, Velanovich, Vic, Karachristos, Andreas, Douglas, Wade G., Legaspi, Adrian, Allan, Bassan J., Meredith, Kenneth, Molina-Vega, Manual A., Bao, Philip, St. Julien, Jamii, Huguet, Kevin L., Green, Lee, Odedina, Folakemi T., Kumar, Nagi B., Simmons, Vani N., George, Thomas J., Vadaparampil, Susan T., Hodul, Pamela J., Arnoletti, J. Pablo, Awad, Ziad T., Bose, Debashish, Jiang, Kun, Centeno, Barbara A., Gwede, Clement K., Malafa, Mokenge, Judge, Sarah M., Judge, Andrew R., Jeong, Daniel, Bloomston, Mark, Merchant, Nipun B., Fleming, Jason B., Trevino, Jose G.
    Publicado 2021
    “…Conclusions: This biorepository addresses a critical gap in PaCa research and has potential to advance translational studies intended to minimize disparities and reduce PaCa-related morbidity and mortality.…”
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    The Florida Pancreas Collaborative Next-Generation Biobank: Infrastructure to Reduce Disparities and Improve Survival for a Diverse Cohort of Patients with Pancreatic Cancer
  4. 303364
    “…BACKGROUND: The COVID-19 pandemic has shined a harsh light on a critical deficiency in our health care system: our inability to access important information about patients’ values, goals, and preferences in the electronic health record (EHR). …”
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    A Novel Patient Values Tab for the Electronic Health Record: A User-Centered Design Approach
  5. 303365
    “…Given its impact on provider wellbeing and quality of care, interventions to help providers manage stress are critical. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-10453-0.…”
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    Psychological and physiological stress and burnout among maternity providers in a rural county in Kenya: individual and situational predictors
  6. 303366
    “…While a 3 ml ABHR volume is reasonable for medium-size hands, the need for an optimized volume of handrub for each individual is critical, as it offers several advantages. Not only it can ensure adequate hand hygiene quality, but also prevent unnecessary costs. …”
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    A large-scale investigation of alcohol-based handrub (ABHR) volume: hand coverage correlations utilizing an innovative quantitative evaluation system
  7. 303367
    “…We hypothesized that the two demethylases play critical roles in mediating the stroke sensitivity. …”
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    X chromosome escapee genes are involved in ischemic sexual dimorphism through epigenetic modification of inflammatory signals
  8. 303368
    “…As pressure mounted to scale back measures, understanding public priorities was critical. We assessed initial public adherence with and support for stay-at-home orders in nations and cities with different SARS-CoV-2 infection and COVID-19 death rates. …”
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    Early public adherence with and support for stay-at-home COVID-19 mitigation strategies despite adverse life impact: a transnational cross-sectional survey study in the United States and Australia
  9. 303369
    “…BACKGROUND: Maternal and child health are important issues for global health policy, and the past three decades have seen a significant progress in maternal and child healthcare worldwide. Immunization is a critical, efficient, and cost-effective public health intervention for newborns. …”
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    Maternal healthcare utilization and full immunization coverage among 12–23 months children in Benin: a cross sectional study using population-based data
  10. 303370
    “…We tested whether, in case of Vt = 6 mL/kg, the effects of PLR could be assessed through changes in PPV (ΔPPV(PLR)) or in IVCDV (ΔIVCDV(PLR)) rather than changes in cardiac output, and whether the effects of the Vt challenge could be assessed by changes in IVCDV (ΔIVCDV(Vt)) rather than changes in PPV (ΔPPV(Vt)). METHODS: In 30 critically ill patients without spontaneous breathing and cardiac arrhythmias, ventilated with Vt = 6 mL/kg, we measured cardiac index (CI) (PiCCO2), IVCDV and PPV before/during a PLR test and before/during a Vt challenge. …”
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    Do changes in pulse pressure variation and inferior vena cava distensibility during passive leg raising and tidal volume challenge detect preload responsiveness in case of low tidal volume ventilation?
  11. 303371
    “…However, appropriate reference gene(s) selection remains a critical and challenging subject in which inappropriate reference gene selction can distort results leading to false interpretations. …”
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    Optimizations for identifying reference genes in bone and cartilage bioengineering
  12. 303372
    “…CONCLUSION: With increasing ART exposure, viral load monitoring is critical for early detection of treatment failure in RLS. …”
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    Virologic response of treatment experienced HIV-infected Ugandan children and adolescents on NNRTI based first-line regimen, previously monitored without viral load
  13. 303373
    “…BACKGROUND: The COVID-19 pandemic has generated worldwide scarcity of critical resources to protect against and treat disease. …”
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    Online Artículo Texto
    Protecting providers and patients: results of an Internet survey of health care workers’ risk perceptions and ethical concerns during the COVID-19 pandemic
  14. 303374
    “…Nurses are on the frontlines of healthcare and play a critical role in promoting HPV vaccination and parent-child sexual health communication. …”
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    Effects of a randomized controlled trial of a brief, student-nurse led, parent-based sexual health intervention on parental protective factors and HPV vaccination uptake
  15. 303375
    “…As therapy response is influenced by age-dependent changes, pharmacokinetic processes and disease course it is important to consider developmental changes in bDMARDs/JAK inhibitor use in PiRD patients. As such it is critical to collaborate and conduct international RCTs to appropriately investigate and characterize efficacy, safety and pharmacokinetics of bDMARDs/JAK inhibitors in paediatric rheumatology. …”
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    Biologic disease modifying antirheumatic drugs and Janus kinase inhibitors in paediatric rheumatology – what we know and what we do not know from randomized controlled trials
  16. 303376
    “…A collaborative research team made up of researchers with and without lived experience of mental distress will conduct qualitative investigations with service users, caregivers and IEHT staff teams to explore critical ingredients and interactions between implementation processes, treatment processes, and outcomes from a stakeholder perspective. …”
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    Implementation, efficacy, costs and processes of inpatient equivalent home-treatment in German mental health care (AKtiV): protocol of a mixed-method, participatory, quasi-experimental trial
  17. 303377
    “…Health systems are struggling to manage a fluctuating volume of critically ill patients with COVID-19 while continuing to provide basic surgical services and expand capacity to address operative cases delayed by the pandemic. …”
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    Prioritizing Surgical Services during on-Going Pandemic Response: Modification and Reliability of the Medically Necessary Time Sensitive Surgery (MeNTS) Scoring Tool
  18. 303378
    “…CONCLUSIONS: Vitamin D plus BPA at concentration of 10 nM boosted the adipogenesis during the critical stages of adipocytes development, whereas it seems to inhibit this process at concentration of 0.1 nM.…”
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    Molecular mechanisms of vitamin D plus Bisphenol A effects on adipogenesis in human adipose-derived mesenchymal stem cells
  19. 303379
    “…CONCLUSION: The burden of the ongoing pandemic on the mental health status of residents is very alarming and so providing residents with psychological counseling and support is needed. Also, critical implications on the flow of residency training programs have been noticed. …”
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    The impact of COVID-19 pandemic on training and mental health of residents: a cross-sectional study
  20. 303380
    “…Actionable steps included implementing a system of ongoing feedback that is critical for the sustainability of the Ethics service role. …”
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    Identifying disincentives to ethics consultation requests among physicians, advance practice providers, and nurses: a quality improvement all staff survey at a tertiary academic medical center
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