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  1. 303601
    “…During the Objective Structured Clinical Examination A test, participants in the VR group performed better on the critical step of positioning the head and clearing the airway (VR group: 77/90, 86%; control group: 57/88, 65%; P=.002). …”
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    Using Mobile Virtual Reality Simulation to Prepare for In-Person Helping Babies Breathe Training: Secondary Analysis of a Randomized Controlled Trial (the eHBB/mHBS Trial)
  2. 303602
    por Farley, Shannon M., Wang, Chunhui, Bray, Rachel M., Low, Andrea Jane, Delgado, Stephen, Hoos, David, Kakishozi, Angela N., Harris, Tiffany G., Nyirenda, Rose, Wadonda, Nellie, Li, Michelle, Amuri, Mbaraka, Juma, James, Kancheya, Nzali, Pietersen, Ismela, Mutenda, Nicholus, Natanael, Salomo, Aoko, Appolonia, Ngugi, Evelyn W., Asiimwe, Fred, Lecher, Shirley, Ward, Jennifer, Chikwanda, Prisca, Mugurungi, Owen, Moyo, Brian, Nkurunziza, Peter, Aibo, Dorothy, Kabala, Andrew, Biraro, Sam, Ndagije, Felix, Musuka, Godfrey, Ndongmo, Clement, Shang, Judith, Dokubo, Emily K., Dimite, Laura E., McCullough‐Sanden, Rachel, Bissek, Anne‐Cecile, Getaneh, Yimam, Eshetu, Frehywot, Nkumbula, Tepa, Tenthani, Lyson, Kayigamba, Felix R., Kirungi, Wilford, Musinguzi, Joshua, Balachandra, Shirish, Kayirangwa, Eugenie, Ayite, Ayiyi, West, Christine A., Bodika, Stephane, Sleeman, Katrina, Patel, Hetal K., Brown, Kristin, Voetsch, Andrew C., El‐Sadr, Wafaa M., Justman, Jessica J.
    Publicado 2022
    “…INTRODUCTION: Achieving optimal HIV outcomes, as measured by global 90‐90‐90 targets, that is awareness of HIV‐positive status, receipt of antiretroviral (ARV) therapy among aware and viral load (VL) suppression among those on ARVs, respectively, is critical. However, few data from sub‐Saharan Africa (SSA) are available on older people (50+) living with HIV (OPLWH). …”
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    Progress towards the UNAIDS 90‐90‐90 targets among persons aged 50 and older living with HIV in 13 African countries
  3. 303603
    “…Interferon-α response pathway perhaps is a critical regulation mechanism for the MAIT cell involvement in aGVHD development. …”
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    Mucosal-associated invariant T cells predict increased acute graft-versus-host-disease incidence in patients receiving allogeneic hematopoietic stem cell transplantation
  4. 303604
    “…CONCLUSIONS: Supported by post-mortem data, the cause of death in HF and AF patients is heterogeneous, and the relationships with typical markers of mortality are critically dependent on the mode of death. The poor prognosis in this group demands further attention to improve management beyond anticoagulation. …”
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    Post-mortem examination of high mortality in patients with heart failure and atrial fibrillation
  5. 303605
    “…Adoptive transfer studies revealed that the increased susceptibility of SLAMF7(−/−) mice to EAE is partly B cell dependent and reconstruction of the human CSF SLAMF7-interactome found B cells to be critical to cell–cell communication between SLAMF7-expressing cells. …”
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    SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity
  6. 303606
    “…We also applied the Joanna Briggs Institute critical appraisal instrument for studies reporting prevalence data, the Cochran’s Q-test, Egger’s regression test and the single study deletion technique to respectively examine within-study bias, heterogeneity, across-study bias and sensitivity. …”
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    Africa-wide meta-analysis on the prevalence and distribution of human cystic echinococcosis and canine Echinococcus granulosus infections
  7. 303607
    por Sedilla, Keneth B., Maeda, Takafumi
    Publicado 2022
    “…BACKGROUND: While thermoregulatory behavior is critical for maintaining homeostasis, our knowledge of behavioral thermoeffectors in humid heat is limited compared to the control of autonomic thermoeffectors. …”
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    Autonomic thermoregulatory responses and subjective thermal perceptions upon the initiation of thermal behavior among resting humans in hot and humid environment
  8. 303608
    “…Non-invasive molecular imaging methods have the potential to provide critical insights into the temporal dynamics and follow alterations of receptor expression and metabolism in ischemic stroke. …”
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    In vivo Imaging of Cannabinoid Type 2 Receptors: Functional and Structural Alterations in Mouse Model of Cerebral Ischemia by PET and MRI
  9. 303609
    “…BACKGROUND: The mechanistic target of rapamycin (mTOR) signal pathway plays a critical regulating role in the occurrence and development of cataract. …”
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    Association of mTORC1‑dependent circulating protein levels with cataract formation: a mendelian randomization study
  10. 303610
    “…BACKGROUND: Rapid fluid administration may decrease hemoglobin concentration (Hb) by a diluting effect, which could limit the increase in oxygen delivery (DO(2)) expected with a positive response to fluid challenge in critically ill patients. Our aim was to quantify the decrease in Hb after rapid fluid administration. …”
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    Effects of rapid fluid infusion on hemoglobin concentration: a systematic review and meta-analysis
  11. 303611
    “…CONCLUSIONS: This study suggests that mechanical strength of antibiotic-loaded PMMA bone cement critically decreases even over the short time period of six weeks, which is the recommended interim period in the setting of two-stage revision. …”
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    Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery
  12. 303612
    “…INTRODUCTION: Low birth weight is a global public health problem, with 15–20% of all births globally, described by weight at birth of less than 2500 g ensuing fetal and neonatal mortality and morbidity, poor cognitive growth, and an increased risk of chronic diseases later in life. The prevalence is critical in East Africa where about 11% have low birth weight out of 54% of neonates whose weight was measured at birth. …”
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    Low birth weight and its associated factors in East Gojjam Zone, Amhara, Ethiopia
  13. 303613
    “…The timely detection of severe neutropenia (<500 absolute neutrophil count/μL) is critical in detecting and managing febrile neutropenia. …”
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    Usability Evaluation of a Noninvasive Neutropenia Screening Device (PointCheck) for Patients Undergoing Cancer Chemotherapy: Mixed Methods Observational Study
  14. 303614
    “…No predictor of 100% response emerged in patients with HFEM or CM. CONCLUSIONS: A critical evaluation of headache characteristics indicating peripheral or central sensitization may help in predicting responsiveness to antiCGRP mAbs in HFEM and CM. …”
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    Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients
  15. 303615
    “…Additionally, we treated the human bronchial epithelial (HBE) cells with cigarette smoke extract (CSE), and EVs were derived from the plasma in vitro experiments. The critical pathway involving the relationship between COPD and HUA was eventually validated based on the results of RNA sequencing (RNA-seq) and western blot (WB). …”
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    Extracellular vesicles isolated from hyperuricemia patients might aggravate airway inflammation of COPD via senescence-associated pathway
  16. 303616
    “…This systematic review and meta-analysis aimed to evaluate the effectiveness of early intubation compared to late intubation in patients with severe and critical COVID-19. METHODS: For this study, we searched the MEDLINE, EMBASE, and Cochrane databases as well as one Korean domestic database on July 15, 2021. …”
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    Early intubation and clinical outcomes in patients with severe COVID-19: a systematic review and meta-analysis
  17. 303617
    “…For almost two decades, automation of this critical step of washing/concentrating cells has been feasible. …”
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    Sepax-2 cell processing device: a study assessing reproducibility of concentrating thawed hematopoietic progenitor cells
  18. 303618
    “…CONCLUSIONS: UBE2T is a critical oncogene in many cancers. Moreover, UrCCG classified the LUAD cohort into four subgroups with significantly different survival, molecular features, immune infiltrates, and immunotherapy responses. …”
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    Pan-cancer analysis of UBE2T with a focus on prognostic and immunological roles in lung adenocarcinoma
  19. 303619
    “…BACKGROUND: The prognosis for metastatic and recurrent tumors of the central nervous system (CNS) remains dismal, and the need for newer therapeutic targets and modalities is critical. The cell surface glycoprotein B7H3 is expressed on a range of solid tumors with a restricted expression on normal tissues. …”
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    Phase 1 study of intraventricular (131)I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies
  20. 303620
    “…The results reflected the critical importance of local and international NGOs addressing poor mental health conditions of their employees to prevent mental health outbreaks. …”
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    Job insecurity and mental health related outcomes among the humanitarian workers during COVID-19 pandemic: a cross-sectional study
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