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  1. 303661
    “…BACKGROUND: Brain microvascular endothelial cells (BMECs) play a major role in the blood–brain barrier (BBB), and are critical for establishing an in vitro BBB model. Currently, iPSC-derived BMECs (iBMECs) have been used to construct in vitro BBB models with physiological barrier functions, such as high trans-endothelial electrical resistance (TEER) and expression of transporter proteins. …”
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    The maturation of iPS cell-derived brain microvascular endothelial cells by inducible-SOX18 expression
  2. 303662
    por Smith, Emily R, Oakley, Erin, Grandner, Gargi Wable, Ferguson, Kacey, Farooq, Fouzia, Afshar, Yalda, Ahlberg, Mia, Ahmadzia, Homa, Akelo, Victor, Aldrovandi, Grace, Tippett Barr, Beth A, Bevilacqua, Elisa, Brandt, Justin S, Broutet, Nathalie, Fernández Buhigas, Irene, Carrillo, Jorge, Clifton, Rebecca, Conry, Jeanne, Cosmi, Erich, Crispi, Fatima, Crovetto, Francesca, Delgado-López, Camille, Divakar, Hema, Driscoll, Amanda J, Favre, Guillaume, Flaherman, Valerie J, Gale, Chris, Gil, Maria M, Gottlieb, Sami L, Gratacós, Eduard, Hernandez, Olivia, Jones, Stephanie, Kalafat, Erkan, Khagayi, Sammy, Knight, Marian, Kotloff, Karen, Lanzone, Antonio, Le Doare, Kirsty, Lees, Christoph, Litman, Ethan, Lokken, Erica M, Laurita Longo, Valentina, Madhi, Shabir A, Magee, Laura A, Martinez-Portilla, Raigam Jafet, McClure, Elizabeth M, Metz, Tori D, Miller, Emily S, Money, Deborah, Moungmaithong, Sakita, Mullins, Edward, Nachega, Jean B, Nunes, Marta C, Onyango, Dickens, Panchaud, Alice, Poon, Liona C, Raiten, Daniel, Regan, Lesley, Rukundo, Gordon, Sahota, Daljit, Sakowicz, Allie, Sanin-Blair, Jose, Söderling, Jonas, Stephansson, Olof, Temmerman, Marleen, Thorson, Anna, Tolosa, Jorge E, Townson, Julia, Valencia-Prado, Miguel, Visentin, Silvia, von Dadelszen, Peter, Adams Waldorf, Kristina, Whitehead, Clare, Yassa, Murat, Tielsch, Jim M
    Publicado 2023
    “…Pregnant women with SARS-CoV-2 infection—as compared with uninfected pregnant women—were at significantly increased risk of maternal mortality (10 studies; n=1490; RR 7.68, 95% CI 1.70 to 34.61); admission to intensive care unit (8 studies; n=6660; RR 3.81, 95% CI 2.03 to 7.17); receiving mechanical ventilation (7 studies; n=4887; RR 15.23, 95% CI 4.32 to 53.71); receiving any critical care (7 studies; n=4735; RR 5.48, 95% CI 2.57 to 11.72); and being diagnosed with pneumonia (6 studies; n=4573; RR 23.46, 95% CI 3.03 to 181.39) and thromboembolic disease (8 studies; n=5146; RR 5.50, 95% CI 1.12 to 27.12). …”
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    Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis
  3. 303663
    “…CONCLUSION: This study found that nearly three-quarters of all antibiotics sold were without prescription, including antibiotics on the list of critically important antimicrobials for human medicine. …”
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    Gender and urban-rural influences on antibiotic purchasing and prescription use in retail drug shops: a one health study
  4. 303664
    “…METHODS: Prospective observational study of adult patients suffering dyspnea. Prehospital critical care physicians registered a suspected diagnosis based on clinical examination alone, performed POCUS of the heart and lungs, and finally registered suspected diagnoses based on their clinical examination supplemented with POCUS. …”
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    PrehospitaL Ultrasound in Undifferentiated DyspnEa (PreLUDE): a prospective, clinical, observational study
  5. 303665
    “…Understanding TD utilization trends is critical in defining the role of virtual care for improving universal care access, optimizing resources, and informing future healthcare models for all patient populations.…”
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    Teledermatology May Benefit Marginalized Populations: National and Institutional Trends during the COVID-19 Pandemic
  6. 303666
    “…BACKGROUND: Post-transcriptional regulation plays a critical role in controlling biological processes such as aging. …”
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    EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cells
  7. 303667
    “…BACKGROUND: Over-the-counter antibiotic access is common in low-and-middle-income countries and this may accelerate antimicrobial resistance. Our study explores critical aspects of the drug seller–client interaction and antibiotic dispensing patterns for simulated COVID-19 symptoms during the pandemic in two study sites in Tanzania and Uganda, countries with different government responses to the pandemic. …”
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    Antibiotic dispensing practices during COVID-19 and implications for antimicrobial resistance (AMR): parallel mystery client studies in Uganda and Tanzania
  8. 303668
    “…BACKGROUND: An extensive body of animal literature supports the premise that maternal obesity during pregnancy can alter the development of the fetal hypothalamus (HTH, a critical regulator of energy balance) with implications for offspring obesity risk (i.e., long-term energy imbalance). …”
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    Maternal pre-pregnancy body mass index is associated with newborn offspring hypothalamic mean diffusivity: a prospective dual-cohort study
  9. 303669
    “…Substance P (SP), through binding to neurokinin 1 receptor (NK1R), and pyruvate kinase M2 (PKM2) play critical roles in cancer development and progression via modulating the tumor microenvironment. …”
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    Expression of substance P, neurokinin 1 receptor, Ki-67 and pyruvate kinase M2 in hormone receptor negative breast cancer and evaluation of impact on overall survival
  10. 303670
    “…Mechanistically, our single-cell pseudotime analysis of scRNA-seq data and in vitro cell culture study revealed that Wnt-β-catenin and TGFβ1/Smad pathways are critical in regulating CD34(+) cell differentiation toward fibroblasts. …”
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    Single cell and lineage tracing studies reveal the impact of CD34(+) cells on myocardial fibrosis during heart failure
  11. 303671
    “…PATIENTS AND METHODS: This is a secondary analysis of a randomized controlled trial that compared an early RRT initiation strategy with a delayed one in 620 critically ill patients undergoing severe AKI (defined by KDIGO 3). …”
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    Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
  12. 303672
    “…CONCLUSION: We identified outer and inner setting factors of SSPs that were associated with greater naloxone distribution. It is critical to ensure SSPs are adequately resourced to build community support for services and develop service delivery models that maximize naloxone distribution to address the nation’s opioid overdose crisis.…”
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    How do contextual factors influence naloxone distribution from syringe service programs in the USA: a cross-sectional study
  13. 303673
    “…Once the literature body for a gene crosses 10 FPEs, most of the critical fundamental research risk appears overcome and steady incremental research becomes possible. …”
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    About the dark corners in the gene function space of Escherichia coli remaining without illumination by scientific literature
  14. 303674
    “…SP is a prominent strategy used in the Critical Age Periods Impacting the Trajectory of Obesogenic Lifestyles Project, which is an initiative based in NW Tasmania focused on assessing obesity prevention capacity. …”
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    “An Ounce of Prevention is Worth a Pound of Cure”: Proposal for a Social Prescribing Strategy for Obesity Prevention and Improvement in Health and Well-being
  15. 303675
    “…CONCLUSION: Two signaling axes critical in the progression of CP to PDAC were screened out. …”
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    Multi-level integrative analysis of the roles of lncRNAs and differential mRNAs in the progression of chronic pancreatitis to pancreatic ductal adenocarcinoma
  16. 303676
    “…BACKGROUND: Mammalian cell lines are frequently used as protein expression hosts because of their ability to correctly fold and assemble complex proteins, produce them at high titers, and confer post-translational modifications (PTMs) critical to proper function. Increasing demand for proteins with human-like PTMs, particularly viral proteins and vectors, have made human embryonic kidney 293 (HEK293) cells an increasingly popular host. …”
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    Comparison of vector elements and process conditions in transient and stable suspension HEK293 platforms using SARS-CoV-2 receptor binding domain as a model protein
  17. 303677
    por Leahu, Marius Constantin
    Publicado 2013
    “…We built this service on top of the OASIS XACML industry standard while paying special attention to the critical non-functional aspects like availability, performance, scalability and monitoring. …”
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    Access Control in the ATLAS TDAQ Online Cluster
  18. 303678
    por Quirk, Thomas J, Cummings, Simone
    Publicado 2017
    “…Presents key steps and examples to solve practical, easy-to-understand social work problems using Excel Contains 163 illustrations in color Suitable for undergraduate and graduate students No background in statistics is required Guides students through not only statistical formulas but also the processes and reasoning that support statistical theory Focuses exclusively on building a critical foundation for students and practitioners Explains statistical theory and formulas in clear language without bogging the reader down in mathematical fine points Features five appendices with tests, answers and statistical formulas Includes specific objectives for concepts in each chapter, as well as practice problems with answers Saves instructors valuable class time by allowing students to learn how to use Excel to solve practical social work problems outside of class time Tom Quirk is Professor of Marketing in the Walker School of Business and Technology at Webster University in St. …”
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    Excel 2016 for social work statistics: a guide to solving practical problems
  19. 303679
    por Fallavollita, Francesco
    Publicado 2019
    “…Aging is one of the most critical limitations of the use of gaseous detectors in strong radiation environments; it includes all the processes that lead to a significant and permanent degradation of the detection performences: gain drop, non-uniformity, dark current, discharge, etc. …”
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    Triple-Gas Electron Multiplier technology for future upgrades of the CMS experiment: construction and certification of the CMS GE1/1 detector and longevity studies
  20. 303680
    por Sahoo, Pragati
    Publicado 2019
    “…Theoretically, there are several signatures of first-order phase transition and the critical point has been proposed. The color string percolation model (CSPM) is an approach to investigate the particle production through the percolation of color strings and the phase structure of the hadronic matter. …”
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    Measurement of K*(892)± in Proton+Proton collisions with ALICE at the LHC and Study of Particle Production using Color String Percolation Model
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