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  1. 303801
    “…BACKGROUND: Infections caused by multi-drug resistant (MDR) Gram-negative pathogens are increasingly problematic in healthcare settings and are associated with worse clinical outcomes in critically ill patients. We conducted a multicenter real-world evaluation of culture turn-around time (TAT), associated inadequate empiric (IET) and definitive therapy (IDT) in carbapenem susceptible (Carb-S) and non-susceptible (Carb-NS) Enterobacterales (ENT) and P. aeruginosa (PSA). …”
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    1931. Real-world evaluation of adequacy of empiric and definitive therapy in carbapenem susceptible and non-susceptible Enterobacterales and Pseudomonas aeruginosa by time to culture result: A multicenter analysis
  2. 303802
    “…BACKGROUND: Rapid identification and antimicrobial susceptibility testing (AST) of pathogens causing bloodstream infections (BSI) is critical to providing accurate patient therapy. We conducted a multicenter evaluation of inadequate empiric (IET) and definitive therapy (IDT) from culture turn-around-time (TAT) in carbapenem susceptible (Carb-S) and carbapenem non-susceptible (Carb-NS) Enterobacterales (ENT) and P. aeruginosa (PSA) from blood specimens. …”
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    180. Multicenter Analysis of Adequacy of Empiric and Definitive Therapy by Time to Culture Result in Hospitalized Patients with Blood Culture Positive for Carbapenem Resistant and Susceptible Enterobacterales and Pseudomonas aeruginosa
  3. 303803
    “…Data extracted from the electronic medical record and collected in a central database. Acute critical illness was measured through the Pitt Bacteremia Score, and chronic comorbidities through the Charlson Comorbidity Index. …”
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    170. Outcomes after Stenotrophomonas maltophilia bloodstream infection
  4. 303804
    “…Most of the systematic reviews (72%) were classified as critically low quality, only 2% as high quality and 25% were published since the COVID‐19 pandemic. …”
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    Digital interventions to reduce social isolation and loneliness in older adults: An evidence and gap map
  5. 303805
    “…CONCLUSIONS: CRTAT, a point-of-care data entry tool, more accurately categorized patients into risk tiers (particularly those hospitalized), underscored by its ability to identify critical factors in patient history and clinical status. …”
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    Comparing a Data Entry Tool to Provider Insights Alone for Assessment of COVID-19 Hospitalization Risk: Pilot Matched Cohort Comparison Study
  6. 303806
    “…Participants interacted with the app while thinking aloud, and any issues raised were classified as critical, serious, or minor by observers. This information was used to create an improved and functional smartphone app for evaluation in phase 2. …”
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    A Novel System for the Device-Based Measurement of Physical Activity, Sedentary Behavior, and Sleep (Motus): Usability Evaluation
  7. 303807
    “…CONCLUSION: Our study revealed the critical role of epigenetic regulation of T cell immunity-related genes in the progression of SS-related dry eye and reminded us that DNA methylation-regulated genes such as Itgal, Vav1, Irf4 and Icosl may be used as new targets for SS-related dry eye therapy.…”
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    Integrated DNA Methylation and Transcriptomics Analyses of Lacrimal Glands Identify the Potential Genes Implicated in the Development of Sjögren’s Syndrome-Related Dry Eye
  8. 303808
    “…By specialty, information was most requested for gynecology and obstetrics (n = 71; 26%), dermatology (n = 28; 10%), urology (n = 22; 8%), and gastroenterology (n = 18; 7%), with anesthesiology, critical care, physical medicine and rehabilitation, and pathology being the least requested (n = 0; 0%). …”
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    Web-Based Asynchronous Teleconsulting for Consumers in Colombia: A Case Study
  9. 303809
    “…Biological and clinical observations suggest that initial marked reduction of resistant clones may be critical in any attempt to improve long-term results in advanced neuroblastoma (NB). …”
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    Treatment of advanced neuroblastoma: feasibility and therapeutic potential of a novel approach combining 131-I-MIBG and multiple drug chemotherapy
  10. 303810
    por Brand, Richard A.
    Publicado 2008
    “…A postoperative dressing which maintained downward and backward pressure on the scapula was, he insisted, a critical detail. He reported two cases with good results in followup at 15 and 16 months postoperatively [4]. …”
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    Congenital Elevation of the Scapula: Robert D. Schrock MD (1884–1960) The 9th President of the AAOS 1940
  11. 303811
    “…Improving the uptake of quality antenatal and intrapartum care is critical for evidence-based interventions to generate an impact at the population level. …”
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    Delivering interventions to reduce the global burden of stillbirths: improving service supply and community demand
  12. 303812
    “…Linear regression was used to determine the slopes (critical velocity, CV) and y-intercepts (anaerobic running capacity, ARC) of these relationships to assess aerobic and anaerobic performances, respectively. …”
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    The effects of a pre-workout supplement containing caffeine, creatine, and amino acids during three weeks of high-intensity exercise on aerobic and anaerobic performance
  13. 303813
    “…BACKGROUND: There has been increasing interest in measuring under-five mortality as a health indicator and as a critical measure of human development. In countries with complete vital registration systems that capture all births and deaths, under-five mortality can be directly calculated. …”
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    Measuring Under-Five Mortality: Validation of New Low-Cost Methods
  14. 303814
    “…We suggest that all nationally representative survey programs with adequate sample size ought to implement this critical module for tracking adult mortality in order to more reliably understand the levels and patterns of adult mortality, and how they are changing. …”
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    Measuring Adult Mortality Using Sibling Survival: A New Analytical Method and New Results for 44 Countries, 1974–2006
  15. 303815
    “…BACKGROUND: Cytochrome P450 2B6 (CYP2B6) metabolizes efavirenz and nevirapine, the major core antiretroviral drugs for HIV in Thailand. Rifampicin, a critical component of tuberculosis (TB) therapy is a potent inducer of CYP enzyme activity. …”
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    Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults
  16. 303816
    “…This makes first aid critically important before any definitive operative procedure is undertaken. …”
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    First aid and treatment for cervical spinal cord injury with fracture and dislocation
  17. 303817
    “…The expenditure of energy and cellular resources toward secretion of a critical protein during viral biogenesis without apparent specific function requires further investigation. …”
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    Shedding of soluble glycoprotein 1 detected during acute Lassa virus infection in human subjects
  18. 303818
    “…Sucrose transporters (SUC/SUT) play a critical role in phloem loading and unloading. Photoassimilate transport is a major limiting factor for seed yield. …”
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    Characterization of Sucrose transporter alleles and their association with seed yield-related traits in Brassica napus L
  19. 303819
    “…BACKGROUND: Disseminating palliative care is a critical task throughout the world. Several outcome studies explored the effects of regional palliative care programs on a variety of end-points, and some qualitative studies investigated the process of developing community palliative care networks. …”
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    A region-based palliative care intervention trial using the mixed-method approach: Japan OPTIM study
  20. 303820
    “…BACKGROUND: Detailed cause of death data by age group and sex are critical to identify key public health issues and target interventions appropriately. …”
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    Causes of death in Tonga: quality of certification and implications for statistics
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