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  1. 303861
    “…BACKGROUND: MicroRNAs are increasingly being appreciated as critical players in human diseases, and questions concerning the role of microRNAs arise in many areas of biomedical research. …”
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    miRiaD: A Text Mining Tool for Detecting Associations of microRNAs with Diseases
  2. 303862
    “…BACKGROUND: Mid-to-late adolescence is a critical period for initiation of alcohol and drug problems, which can be reduced by targeted brief motivational interventions. …”
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    Online Artículo Texto
    Effectiveness of a Web-Based Screening and Fully Automated Brief Motivational Intervention for Adolescent Substance Use: A Randomized Controlled Trial
  3. 303863
    “…Recent studies have demonstrated stress ultrasonography is a critical tool in the evaluation of the UCL. . No study, has dynamically evaluated the UCL in uninjured professional pitchers under stress, nor has any study evaluated the ability of UCL reconstruction (UCLR) to restore normal kinematics. …”
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    Professional Pitchers Display Differences in Ulnar Collateral Ligament Morphology and Elbow Gapping Following UCLR Compared to Uninjured Pitchers
  4. 303864
    “…Creating teams with the required pools of expertise and insight regarding needs is critical. The cyclical, iterative process of developing mHealth innovations needs to be viewed as a whole with supportive theoretical frameworks. …”
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    Designing, Implementing, and Evaluating Mobile Health Technologies for Managing Chronic Conditions in Older Adults: A Scoping Review
  5. 303865
    “…Use of VPAC1 antagonists in WT mice prior to EAE induction also support a critical role for VPAC1 signaling for the development of EAE. …”
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    VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage
  6. 303866
    “…Therefore, identification of structural changes of OA that may precede the onset of symptoms is of critical importance for determining risk factors for the initiation and progression of post-traumatic OA in addition to measuring the effectiveness of potential disease-modifying treatments. …”
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    Predictors of Lateral Compartment Joint Space Difference at a Minimum of Two Years after ACL Reconstruction: Data from the Moon Onsite Cohort
  7. 303867
    “…UPDRS scores play a critical role in predicting diagnosis, which is expected based on the clinical definition of Parkinson’s disease. …”
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    Predictive Big Data Analytics: A Study of Parkinson’s Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations
  8. 303868
    “…Therefore, active follow-up could improve method continuation especially in the critical post-insertion period.…”
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    Comparing Effectiveness of Active and Passive Client Follow-Up Approaches in Sustaining the Continued Use of Long Acting Reversible Contraceptives (LARC) in Rural Punjab: A Multicentre, Non-Inferiority Trial
  9. 303869
    “…While findings of effectiveness must be reproduced in a RCT to proof causation, they pave the way for a new generation of digital health interventions leveraging smartphone sensors to provide context sensitive information for in-situ support and unobtrusive monitoring of critical mental health states.…”
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    Online Artículo Texto
    Mobile Sensing and Support for People With Depression: A Pilot Trial in the Wild
  10. 303870
    “…CONCLUSIONS: Increasing case detection is critical to improving outcomes in India’s TB cascade of care, especially for smear-negative and MDR TB patients. …”
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    The Tuberculosis Cascade of Care in India’s Public Sector: A Systematic Review and Meta-analysis
  11. 303871
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    A profile of metabolic acidosis in patients with sepsis in an Intensive Care Unit setting
  12. 303872
    “…We suggest that telehealth-supported care can fulfill an important role in enabling patients with COPD to better manage their condition and remain out of hospital, but adequate resourcing and timely response to alerts is a critical factor in supporting patients to remain at home. …”
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    Does Telehealth Monitoring Identify Exacerbations of Chronic Obstructive Pulmonary Disease and Reduce Hospitalisations? An Analysis of System Data
  13. 303873
    “…Our goal was to investigate the impact on splicing of a set of reported variants of BRCA2 exons 17 and 18 to assess their role in hereditary breast cancer and to identify critical regulatory elements that may constitute hotspots for spliceogenic variants. …”
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    Functional classification of DNA variants by hybrid minigenes: Identification of 30 spliceogenic variants of BRCA2 exons 17 and 18
  14. 303874
    “…The higher educational system shoulders some critical responsibilities in the economic, social, cultural and educational development and growth in the communities. …”
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    Comparative Analysis of Family Medicine Education and Exams at Cathedras of Family Medicine of Universities in Southeastern Europe - “Splitska inicijativa”, Sarajevo, 2017
  15. 303875
    por Pyke, Robert, Clayton, Anita
    Publicado 2016
    “…INTRODUCTION: Counts of satisfying sexual events (SSEs) per month have been criticized as an end point in treatment trials of women with hypoactive sexual desire disorder (HSDD) but grounding improvement in sexual desire by assessing changes in sexual behavior remains of some importance. …”
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    What Sexual Behaviors Relate to Decreased Sexual Desire in Women? A Review and Proposal for End Points in Treatment Trials for Hypoactive Sexual Desire Disorder
  16. 303876
    “…BACKGROUND: The identification of anaerobic metabolism in critically ill patients is a challenging task. Observational studies have suggested that the ratio of venoarterial PCO(2) (P(v–a)CO(2)) to arteriovenous oxygen content difference (C(a–v)O(2)) might be a good surrogate for respiratory quotient (RQ). …”
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    Venoarterial PCO(2)-to-arteriovenous oxygen content difference ratio is a poor surrogate for anaerobic metabolism in hemodilution: an experimental study
  17. 303877
    “…The results validate the findings of earlier laboratory studies on mosquito activity at LLINs, and reinforce the key role of multiple brief contacts at the net roof as the critical LLIN mode of action. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12936-017-1909-6) contains supplementary material, which is available to authorized users.…”
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    Host-seeking activity of a Tanzanian population of Anopheles arabiensis at an insecticide treated bed net
  18. 303878
    “…The end user perspective is critical as end user interest in and use of mHealth technologies will ultimately drive the efficacy of these tools. …”
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    Health App Use Among Individuals With Symptoms of Depression and Anxiety: A Survey Study With Thematic Coding
  19. 303879
    “…CONCLUSIONS: This evaluation study showed that program monitoring in rural West China was critically important for understanding program implementation and adherence trends. …”
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    Monitoring and evaluating the adherence to a complementary food supplement (Ying Yang Bao) among young children in rural Qinghai, China: a mixed methods evaluation study
  20. 303880
    “…Among the 25 leading causes of death globally, the Review Groups associated with the largest number of causes were: 1) Infectious Diseases, 2) Anaesthesia, Critical, and Emergency Care, 3) Injuries, 4) Pregnancy and Childbirth (PC), and 5) Neonatal. …”
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    Descriptive analysis of cochrane child-relevant systematic reviews: an update and comparison between 2009 and 2013
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