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  1. 303941
    “…Studies were assessed for risk of bias using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data. …”
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    Serogroup-specific meningococcal carriage by age group: a systematic review and meta-analysis
  2. 303942
    “…Based on the results obtained, we recommend that improvement of institutional settings such as the availability of AI service providers, as well as better access to services such as water, animal feed, and animal health provision, be treated as critical components to focus on for enhanced AI adoption. …”
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    Multi-country investigation of factors influencing breeding decisions by smallholder dairy farmers in sub-Saharan Africa
  3. 303943
    “…MicroRNAs (miRs) have been identified as critical regulatory molecules in myocardial ischemia/reperfusion injury; however, the exact expression profile of miR-199a-5p in reperfusion injury and the underlying pathogenic mechanisms remain unclear. …”
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    Downregulation of microRNA-199a-5p attenuates hypoxia/reoxygenation-induced cytotoxicity in cardiomyocytes by targeting the HIF-1α-GSK3β-mPTP axis
  4. 303944
    “…The objective of our systematic review and meta-analysis was to evaluate the efficacy and safety of autologous implantation of stem cells in patients with PAD critically, compared with active controls and placebo. …”
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    Autologous stem cell therapy for peripheral arterial disease: a systematic review and meta-analysis of randomized controlled trials
  5. 303945
    “…Overall, we concluded that increased ACP-Δ9D and CoA-Δ9D levels coupled with decreased KASII and FAE1 activity is a critical event for high C16:1n7 accumulation and that the coordinated high expression of WRI1, GPD1, and DGAT1 genes resulted in high oil accumulation in SBP. …”
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    RNA-seq data reveals a coordinated regulation mechanism of multigenes involved in the high accumulation of palmitoleic acid and oil in sea buckthorn berry pulp
  6. 303946
    “…Quality improvement efforts have been evaluated within individual clinical settings, but patterns of care across its continuum, although a critical component of chronic disease management, have not been studied. …”
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    Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients
  7. 303947
    “…Coding was simplified to enable future revisions by nontechnical staff—critical for context-specific adaptations for scale-up. …”
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    Development and Implementation of a Mobile Phone–Based Prevention of Mother-To-Child Transmission of HIV Cascade Analysis Tool: Usability and Feasibility Testing in Kenya and Mozambique
  8. 303948
    “…Robust evaluation is critical to determine their impact; however, an RCT design may not be feasible in this setting. …”
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    A Smartphone App to Assist Smoking Cessation Among Aboriginal Australians: Findings From a Pilot Randomized Controlled Trial
  9. 303949
    “…BACKGROUND: Ischemia-reperfusion injury (IRI) is an antigen-independent, innate immune response to arterial occlusion and ischemia with subsequent paradoxical exacerbation after reperfusion. IRI remains a critical problem after vessel occlusion and infarction or during harvest and surgery in transplants. …”
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    Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice
  10. 303950
    “…These results demonstrate that sustained inhibition of GABABR signaling during the critical postnatal period of development and maturation of the gonadotropic axis profoundly alters key ARC gene expression such as Kiss1, Pdyn, Tac2, altering sexual differentiation (AGI) and BW. …”
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    MON-222 Blocking GABAB Receptors (GABABR) from Birth to Weaning in Mice Induces Profound Changes in the Gonadotropic Axis
  11. 303951
    por Imam, Shahnawaz, Jaume, Juan
    Publicado 2019
    “…Regulatory T (Treg) cells play a critical role in maintenance of tolerance and are ideal for development of therapies designed to suppress inflammation and autoimmunity. …”
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    MON-LB033 Unleashing the Anti-Inflammatory Potential of Treg Cells Against Type I Diabetes Using Advanced Chimeric Antigen Receptor Technology
  12. 303952
    “…Understanding the interaction between these processes and their net effects on bone and muscle metabolism in vivo is critical in informing our approach to managing these patients. …”
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    SAT-003 Therapeutic Glucocorticoids Prevent Local and Systemic Bone Loss but Exacerbate Muscle Wasting When Administered in Chronic Inflammation
  13. 303953
    “…Interestingly, crosstalk between MuSC and endothelial cells via vascular endothelial growth factor (VEGF) is critical for proper muscle regeneration. It is unknown if local T3 generation by D2 influences interactions between MuSCs and endothelial cells. …”
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    SAT-LB095 The Role of Type 2 Deiodinase in Interactions Between Muscle Stem Cells and Endothelial Cells
  14. 303954
    “…These include higher female levels of Dax-1 (Nr0b1), a nuclear receptor critically involved in adrenal development/steroidogenesis, whereas male adrenals exhibit higher levels of the androgen-metabolizing enzyme, 5α-reductase (Srd5a2). …”
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    SAT-LB062 Adrenal Sexual Dimorphism Is Abolished by Tissue-Targeted Deletion of the Androgen Receptor
  15. 303955
    “…Taken together, these data suggest that skeletal muscle specific KLF15 is critical in the regulation of lipid handling and necessary for optimal PPARδ-mediated regulation of skeletal muscle lipid metabolism. …”
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    SUN-LB006 Skeletal Muscle Krüppel-Like Factor 15 and PPARd Cooperate to Regulate Skeletal Muscle Lipid Metabolism
  16. 303956
    por Wong, Thomas, Dokun, Ayotunde
    Publicado 2019
    “…We previously identified ADAM12 as a gene that is upregulated in ischemic hind limb of mice and play a critical role in perfusion recovery following induction of experimental peripheral arterial disease. …”
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    SUN-078 ADAM12 Is a Direct Target of mir29a: Implications for Impaired Post-Ischemic Adaptation in Diabetes
  17. 303957
    “…Early diagnosis and treatment of mesenteric ischemia in critical in influencing the survival. Unless otherwise noted, all abstracts presented at ENDO are embargoed until the date and time of presentation. …”
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    SUN-LB025 Superior Mesenteric Artery Thrombosis: An Uncommon Complication of Diabetic Ketoacidosis
  18. 303958
    “…As current histopathologic classification systems are hindered by poor reproducibility and lack of predictive value, new prognostic markers are critically needed. In adults, methylation profiling can distinguish benign from malignant ACT, but similar data on pediatric ACT have not been reported. …”
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    OR02-1 DNA Methylation Profiling in Pediatric Adrenocortical Tumors Reveals Distinct Methylation Signatures with Prognostic Significance: A Report from the International Pediatric Adrenocortical Tumor Registry
  19. 303959
    “…Collectively, these results demonstrate that S216 phosphorylation is critical for mouse mammary gland development and S167 phosphorylation is required for MCF-7 breast tumor response to estradiol and tamoxifen.…”
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    OR26-2 Phosphorylation of Estrogen Receptor Alpha is Required for Mammary Gland Development and MCF-7 Breast Tumor Response to Estradiol and Tamoxifen
  20. 303960
    “…Importantly, this study provides critical information for the design of a larger phase III clinical trial investigating Disease Modifying effect of HYMOVIS®. …”
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    Hyaluronan derivative HYMOVIS® increases cartilage volume and type ii collagen turnover in osteoarhritic knee: data from MOKHA study
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