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  1. 303981
    “…Understanding global RSV epidemiology and risk factors for severe illness in low- and middle-income settings is critical as new vaccine candidates become available. …”
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    2629. Respiratory Syncytial Virus Epidemiology and Factors Associated with Severity among Hospitalized Infants in Four Middle-Income Countries, 2015–2017
  2. 303982
    “…BACKGROUND: BDG-guided management of empirical antifungal therapy (AT) has been suggested as a tool to rule out invasive candidiasis (IC) and discontinue AT in critically ill patients. However, some authors reported lower BDG sensibility for non-albicans Candida (NAC) infection. …”
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    2257. BDG-Guided Management of Empirical Antifungal Therapy: a Real-life Experience in a Hospital-Wide Context with High Incidence of Non-albicans Candida Infection
  3. 303983
    “…Early screening and prevention of obesity is critical for averting associated morbidity, disability, and mortality. …”
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    Performance of newly developed body mass index cut-off for diagnosing obesity among Ethiopian adults
  4. 303984
    “…METHODS: A prospective randomized cross-over study was performed in 20 critically ill patients on controlled mechanical ventilation, including 10 patients with acute respiratory distress syndrome (ARDS). …”
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    Adaptive mechanical ventilation with automated minimization of mechanical power—a pilot randomized cross-over study
  5. 303985
    “…BACKGROUND: Maternal smoking during pregnancy is an established risk factor for low infant birth weight, but evidence on critical exposure windows and timing of fetal growth restriction is limited. …”
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    Associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth: Findings from Mendelian randomization and parental negative control studies
  6. 303986
    “…Osseointegration is critical for long-term outcome and requires three design elements including interface connection, porous structure, and initial stability achieved by precise matching and proper fixation methods.…”
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    Three-dimensional-printed custom-made hemipelvic endoprosthesis for primary malignancies involving acetabulum: the design solution and surgical techniques
  7. 303987
    “…Therefore, specific contexts and critical areas need to be identified and managed. Adequate resources and intervention strategies should be addressed not only to perinatal emergencies, but also to the management of mild prematurity/pathology, especially in vulnerable populations for social or orographic reasons. …”
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    Perinatal and newborn care in a two years retrospective study in a first level peripheral hospital in Sicily (Italy)
  8. 303988
    “…METHODS: We conducted 10 focus groups with 85 adults (range 4-10, average 8 per group), 20 stakeholder interviews with family services agency staff, and discussed critical design considerations with 10 prevention scientists and e-learning experts to determine the optimal program content and technology features for SFP Online. …”
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    Formative Evaluation to Build an Online Parenting Skills and Youth Drug Prevention Program: Mixed Methods Study
  9. 303989
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    Clinical evaluation of Ambu(®) Aura-i™ – A new intubating laryngeal mask airway as an independent ventilatory device and a conduit for tracheal intubation in pediatric patients
  10. 303990
    “…CONCLUSION: Drinking water microbial profile strains and resistance to disinfectants are widely varied in cattle farms, and this variance depends on critical factors among which the disinfection process types used disinfectant types and frequency of disinfectants use or change.…”
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    Evaluation of the efficacy of commonly used disinfectants against isolated chlorine-resistant strains from drinking water used in Egyptian cattle farms
  11. 303991
    “…IMPORTANCE: Accurate risk stratification of patients with heart failure (HF) is critical to deploy targeted interventions aimed at improving patients’ quality of life and outcomes. …”
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    Comparison of Machine Learning Methods With Traditional Models for Use of Administrative Claims With Electronic Medical Records to Predict Heart Failure Outcomes
  12. 303992
    “…BACKGROUND: Family planning counseling is critical for women to make informed reproductive and sexual health decisions. …”
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    Quality of Family Planning Counseling in Ethiopia: Trends and determinants of information received by female modern contraceptive users, evidence from national survey data, (2014- 2018)
  13. 303993
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    Early Prediction of Prognosis in Elderly Acute Stroke Patients
  14. 303994
    “…Our present study, which couples a high throughput proteomic analysis and a comparative review of these earlier studies, identifies a few critical molecules as hypothetical candidates that might be important in this infection and for future study.…”
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    High throughput proteomic analysis and a comparative review identify the nuclear chaperone, Nucleophosmin among the common set of proteins modulated in Chikungunya virus infection
  15. 303995
    por MacIntyre, C. Raina
    Publicado 2014
    “…Finally, the discrepant epidemiology warrants critical analysis of all possible explanations, and involvement of all stakeholders in biosecurity, and deliberate release must be seriously considered and at least acknowledged as a possibility.…”
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    The discrepant epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV)
  16. 303996
    “…In all four scenarios, the participants visually fixated 9 of 11 vital signs statistically significantly longer using the avatar (all P<.001). Four critical vital signs (pulse rate, blood pressure, oxygen saturation, and respiratory rate) were visible almost the entire time of a scenario with the avatar; these were only visible for fractions of the observations with conventional monitoring. …”
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    The Mechanisms Responsible for Improved Information Transfer in Avatar-Based Patient Monitoring: Multicenter Comparative Eye-Tracking Study
  17. 303997
    por Xu, MengMeng
    Publicado 2020
    “…RESULTS: These uncertainties have been highlighted recently by the birth of Chinese twins whose C-C chemokine receptor 5 (CCR5) gene had been inactivated via CRISPR-Cas9 to be theoretically protective against HIV infection. CCR5 signaling is critical for the successful infection of human immunodeficiency virus (HIV) and people with homozygous inactivating CCR5-Δ32 mutations have been shown to be protected against HIV infection. …”
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    CCR5-Δ32 biology, gene editing, and warnings for the future of CRISPR-Cas9 as a human and humane gene editing tool
  18. 303998
    “…RESULTS: Unfortunately, there was not a good correlation between RIDT results and RT-PCR results. There was a critical need to develop a clinical syndromic approach for diagnosing hospitalized adults with probable H1N1 pneumonia with negative RIDTs. …”
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    Rapid clinical diagnosis in fatal swine influenza (H1N1) pneumonia in an adult with negative rapid influenza diagnostic tests (RIDTs): Diagnostic swine influenza triad
  19. 303999
    “…Timing interventions to match an individual’s state may be critical to maximizing the efficacy of interventions. …”
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    Assessing Real-Time Moderation for Developing Adaptive Mobile Health Interventions for Medical Interns: Micro-Randomized Trial
  20. 304000
    “…Participants’ comments revealed an appreciation of the empathic and responsible interaction with the TBHC SELMA. A main criticism was that there was no option to enter free text for the patients’ own comments. …”
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    A Smartphone-Based Health Care Chatbot to Promote Self-Management of Chronic Pain (SELMA): Pilot Randomized Controlled Trial
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