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  1. 304061
    “…Our findings facilitate the critical interpretation of DeepGestalt’s results and may help enhance it and similar computer-aided facial phenotyping tools.…”
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    Efficiency of Computer-Aided Facial Phenotyping (DeepGestalt) in Individuals With and Without a Genetic Syndrome: Diagnostic Accuracy Study
  2. 304062
    “…Full trimeric Spike protein studies of the same mutation across all protomers, however, did not exhibit latch release demonstrating the critical importance of interchain interactions across the S1 domain, including RBD-NTD neighboring chain interactions. …”
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    Static all-atom energetic mappings of the SARS-Cov-2 spike protein and dynamic stability analysis of “Up” versus “Down” protomer states
  3. 304063
    Publicado 2020
    “…In addition, the baseline prevalence and intensity data from DeWorm3 suggest that each site has unique epidemiologic characteristics that will be critical in determining correlates of achieving STH transmission interruption in the DeWorm3 trial. …”
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    Baseline patterns of infection in regions of Benin, Malawi and India seeking to interrupt transmission of soil transmitted helminths (STH) in the DeWorm3 trial
  4. 304064
    “…Given this prevalence and that young adulthood is a critical period for the establishment of tobacco and nicotine use, it is important to consider the association between ENDS use and cigarette smoking specifically in this age group. …”
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    Association of Electronic Nicotine Delivery System Use With Cigarette Smoking Progression or Reduction Among Young Adults
  5. 304065
    “…Due to barriers such as limited access to care, half of the women with PPD do not receive treatment. Therefore, it is critical to identify effective and scalable interventions. …”
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    A Mobile Health Mindfulness Intervention for Women With Moderate to Moderately Severe Postpartum Depressive Symptoms: Feasibility Study
  6. 304066
    “…The micro-environmental stimuli and signals in tissues are critical in the macrophage polarization. Toll-like receptors (TLR) ligands, such as lipopolysaccharide (LPS), palmitoyl-3-cysteine-serine-lysine-4 (Pam3CSK4), and ArtinM (mannose-binding lectin) are inductors of M1 subset. …”
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    Pro-inflammatory response ensured by LPS and Pam3CSK4 in RAW 264.7 cells did not improve a fungistatic effect on Cryptococcus gattii infection
  7. 304067
    “…Important limitations of the study are that the strict inclusion criteria could limit the external validity and that the period of vitamin B(12) supplementation might not have covered a critical window for infant growth or brain development. …”
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    Effects of vitamin B(12) supplementation on neurodevelopment and growth in Nepalese Infants: A randomized controlled trial
  8. 304068
    “…These findings highlight the need to pay critical attention to these factors in order to achieve the Sustainable Development Goals 3.1, 3.7, and 3.8. …”
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    Barriers to accessing healthcare among women in Ghana: a multilevel modelling
  9. 304069
    “…BACKGROUND: Natural killer (NK) cells play a critical role in suppressing human immunodeficiency virus-1 (HIV-1) infection, but knowledge on whether and how NK cells affect immune reconstitution in HIV-1-infected individuals who receive antiretroviral therapy (ART) is limited. …”
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    Increased early activation of CD56(dim)CD16(dim/-) natural killer cells in immunological non-responders correlates with CD4(+) T-cell recovery
  10. 304070
    “…The questionnaire was developed and reviewed by physicians with expertise in pediatric critical care, disaster readiness, human factors, and survey development. …”
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    National preparedness survey of pediatric intensive care units with simulation centers during the coronavirus pandemic
  11. 304071
    “…Therefore, the investigation of psychopathologies during the COVID-19 outbreak and emergency response is critical. METHODS: A cross-sectional survey was implemented from July 15/2020 to July 30/2020. …”
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    Depression, anxiety symptoms, Insomnia, and coping during the COVID-19 pandemic period among individuals living with disabilities in Ethiopia, 2020
  12. 304072
    “…Data were double-extracted into a pre-designed template, and studies critically appraised using a modified version of the Public Health Ontario Meta-tool for Quality Appraisal of Public Health Evidence (MetaQAT) tool, with resolution of disagreements by consensus. …”
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    Antibody response to SARS-CoV-2 infection in humans: A systematic review
  13. 304073
    “…Overall safety parameters (safety populations) [Image: see text] CONCLUSION: CFDC demonstrated a comparable safety profile to carbapenems or other cephalosporins and was generally well tolerated in critically ill patients. DISCLOSURES: Yuko Matsunaga, MD, Shionogi Inc. …”
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    1292. Safety Profile of the Novel Siderophore Cephalosporin Cefiderocol in Randomized Phase 2 and Phase 3 Clinical Studies of Serious Gram-Negative Infections
  14. 304074
    “…This study investigates whether the SEIR model, associated to mobility changes parameters, can determine the likelihood of establishing control over an epidemic in a city, state or country. METHODS: The critical step in the prediction of COVID-19 by a SEIR model are the values of the basic reproduction number (R0) and the infectious period, in days. …”
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    479. Mobility Restrictions and COVID-19 Pandemic Outbreak Control
  15. 304075
    “…Identifying likely causative pathogens of co-infections in the era of SARS-CoV-2 is critical for treatment optimization. DISCLOSURES: Laura A. …”
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    373. Comparison of the Epidemiology and Pathogens Cultured from Patients Hospitalized with SARS-CoV-2 Positive versus SARS-CoV-2 Negative in the US: A Multicenter Evaluation
  16. 304076
    “…BACKGROUND: Therapeutic selectivity and drug resistance are critical issues in cancer therapy. Currently, zinc oxide nanoparticles (ZnO NPs) hold considerable promise to tackle this problem due to their tunable physicochemical properties. …”
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    SnO(2)-Doped ZnO/Reduced Graphene Oxide Nanocomposites: Synthesis, Characterization, and Improved Anticancer Activity via Oxidative Stress Pathway
  17. 304077
    “…Moreover, final stroke volume is a critical outcome evaluated in clinical and preclinical experiments to determine therapy or intervention success. …”
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    Machine learning identifies stroke features between species
  18. 304078
    “…IMPORTANCE: Understanding Black vs White differences in pharmacotherapy efficacy and the underlying reasons is critically important to reducing tobacco-related health disparities. …”
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    Assessment of Racial Differences in Pharmacotherapy Efficacy for Smoking Cessation: Secondary Analysis of the EAGLES Randomized Clinical Trial
  19. 304079
    por Lu, Yingjie, Luo, Shuwen, Liu, Xuan
    Publicado 2021
    “…For example, in online depression communities, patients can share their experiences, exchange valuable information, and receive emotional support to help them cope with their disease. Therefore, it is critical to understand how patients with depression develop online social support networks to exchange informational and emotional support. …”
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    Development of Social Support Networks by Patients With Depression Through Online Health Communities: Social Network Analysis
  20. 304080
    “…We found that robust outreach and marketing strategies and support for local staff were critical to the implementation success of the BBC workshop. …”
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    Improving Uptake of a National Web-Based Psychoeducational Workshop for Informal Caregivers of Veterans: Mixed Methods Implementation Evaluation
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