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304241por HONG, Haixiang, ZANG, Kunpeng, CHEN, Yuanyuan, LIN, Yi, LI, Jiaxin, QING, Xuemei, QIU, Shanshan, XIONG, Haoyu, JIANG, Kai, FANG, Shuangxi“…China is approaching a critical period of carbon peak and carbon neutrality. …”
Publicado 2022
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304242“…Thus, HbA(1c) level has been used for the assessment of long-term glycemic control in diabetes; the level of 6.5% HbA(1c) has been certified as a critical cut-off for the diabetes diagnosis. The current commonly used method for HbA(1c) quantification is based on cation-exchange high performance liquid chromatography (CX-HPLC). …”
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304243“…While this study is another series that adds to the many studies across the world that describe the use of pulmonary metastasectomy in CRC, it presents critical data as it is one of the few studies carried out in South America. …”
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304244“…Such processes are increasingly understood in the motor system, however, the role of the basal ganglia, a group of subcortical nuclei that are critical to movement, behaviour, and learning, remain relatively unexplored. …”
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304245por Choudhary, Gaurav S, Pellagatti, Andrea, Agianian, Bogos, Smith, Molly A, Bhagat, Tushar D, Gordon-Mitchell, Shanisha, Sahu, Srabani, Pandey, Sanjay, Shah, Nishi, Aluri, Srinivas, Aggarwal, Ritesh, Aminov, Sarah, Schwartz, Leya, Steeples, Violetta, Booher, Robert N, Ramachandra, Murali, Samson, Maria, Carbajal, Milagros, Pradhan, Kith, Bowman, Teresa V, Pillai, Manoj M, Will, Britta, Wickrema, Amittha, Shastri, Aditi, Bradley, Robert K, Martell, Robert E, Steidl, Ulrich G, Gavathiotis, Evripidis, Boultwood, Jacqueline, Starczynowski, Daniel T, Verma, Amit“…RESULTS: RNA-seq splicing analysis of SF3B1 mutant MDS samples revealed retention of full-length exon 6 of IRAK4, a critical downstream mediator that links the Myddosome to inflammatory NF-kB activation. …”
Publicado 2022
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304246por Richards, Alexander L., Cardno, Alastair, Harold, Gordon, Craddock, Nicholas J., Di Florio, Arianna, Jones, Lisa, Gordon-Smith, Katherine, Jones, Ian, Sellers, Ruth, Walters, James T. R., Holmans, Peter A., Owen, Michael J., O’Donovan, Michael C.“…Understanding the basis of this etiological heterogeneity will be critical for identifying the different pathophysiological processes underlying BD, stratifying patients, and developing precision therapeutics.…”
Publicado 2022
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304247por Havers, Fiona P., Pham, Huong, Taylor, Christopher A., Whitaker, Michael, Patel, Kadam, Anglin, Onika, Kambhampati, Anita K., Milucky, Jennifer, Zell, Elizabeth, Moline, Heidi L., Chai, Shua J., Kirley, Pam Daily, Alden, Nisha B., Armistead, Isaac, Yousey-Hindes, Kimberly, Meek, James, Openo, Kyle P., Anderson, Evan J., Reeg, Libby, Kohrman, Alexander, Lynfield, Ruth, Como-Sabetti, Kathryn, Davis, Elizabeth M., Cline, Cory, Muse, Alison, Barney, Grant, Bushey, Sophrena, Felsen, Christina B., Billing, Laurie M., Shiltz, Eli, Sutton, Melissa, Abdullah, Nasreen, Talbot, H. Keipp, Schaffner, William, Hill, Mary, George, Andrea, Hall, Aron J., Bialek, Stephanie R., Murthy, Neil C., Murthy, Bhavini Patel, McMorrow, Meredith“…IMPORTANCE: Understanding risk factors for hospitalization in vaccinated persons and the association of COVID-19 vaccines with hospitalization rates is critical for public health efforts to control COVID-19. …”
Publicado 2022
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304248“…Conclusion Creating a culture of safety is critical for physician compliance. A comfortable work environment without unreasonable consequences creates an environment where physicians can focus on their health and safety while also doing what is in the workplace’s best interest. …”
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304249por Dong, Mengmeng, Zhang, Jinna, Chen, Qingxiao, He, Donghua, Yan, Haimeng, Zheng, Gaofeng, Han, Xiaoyan, He, Jingsong, Cai, Zhen“…The bone marrow microenvironment (BMM) is highly critical in the pathological process of MM. Many studies have shown that serum interleukin-17A (IL-17A) plays a key role in various infectious diseases, autoimmune diseases, and cancers. …”
Publicado 2022
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304250“…Although many studies have shown that higher SHR means poor outcomes, there is still no absolute evidence that SHR plays a critical role in stroke patients. Hence, we performed a systematic review and meta-analysis aiming to investigate the association between SHR and clinical outcomes in stroke patients. …”
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304251“…Patients in the malnutrition risk group were older (65 y vs. 56 y) and with more severe and critical cases (42.30% vs. 5.20%) and diabetes cases (21.50% vs. 9.80%), worse prognosis (death of 13.80% vs. 0.50%), longer hospital stay (29 days vs. 23 days), lower albumin (31.85 g/L vs. 38.55 g/L) and prealbumin (201.95 mg/L vs. 280.25 mg/L) compared with the normal nutrition group (P were <0.001, respectively). …”
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304252por Berry, Crista-Lee Shahine, Melbourne-Chambers, Roxanne Helene, Harrison, Abigail Natalie, Anzinger, Joshua James, Gordon-Johnson, Kelly-Ann Maxorinthia, Deyde, Varough Mohamed, Christie, Celia Dana Claire“…CONCLUSIONS: In this first report of COVID-19 from the Caribbean, children and adolescents with and without MIS-C were not very severe. Critical care interventions were minimal and outcomes were excellent.…”
Publicado 2022
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304253por Zhao, Yanxi, Xiao, Dengpan, Bai, Huizi, Liu, De Li, Tang, Jianzhao, Qi, Yongqing, Shen, Yanjun“…Investigating different future climate scenarios and their possible impacts on crop production and water consumption is critical for proposing effective responses to climate change. …”
Publicado 2022
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304254por Keppler, Emily Higgins, Mead, Heather, Van Dyke, Marley, Lake, Douglas, Magee, D. Mitchell, Barker, Bridget, Bean, Heather D.“…The current diagnostics for Valley fever are severely lacking due to poor sensitivity and invasiveness, contributing to a 23-day median time-to-diagnosis. There is a critical need for novel diagnostics for detecting and identifying Valley fever lung infections. …”
Publicado 2022
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304255“…Although mucormycosis in a renal transplant recipient is rare, a high index of suspicion and critical microscopic examination is warranted for early initiation of specific therapy which includes liposomal amphotericin B and surgery. …”
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304256por Hota, Bala, Casey, Paul, McIntyre, Anne F, Khan, Jawad, Rab, Shafiq, Chopra, Aneesh, Lateef, Omar, Layden, Jennifer E“…BACKGROUND: Disease surveillance is a critical function of public health, provides essential information about the disease burden and the clinical and epidemiologic parameters of disease, and is an important element of effective and timely case and contact tracing. …”
Publicado 2022
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304257por Tesfay, Neamin, Tariku, Rozina, Zenebe, Alemu, Dejene, Zewdnesh, Woldeyohannes, Fitsum“…BACKGROUND: Globally, three fourth of neonatal deaths occur during the early neonatal period, this makes it a critical time to reduce the burden of neonatal death. …”
Publicado 2022
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304258por Shan, Zack Y., Mohamed, Abdalla Z., Andersen, Thu, Rendall, Shae, Kwiatek, Richard A., Fante, Peter Del, Calhoun, Vince D., Bhuta, Sandeep, Lagopoulos, Jim“…A series of our neuroimaging findings in ME/CFS, including functional MRI (fMRI) signal characteristics and structural changes in brain regions particularly sensitive to hypoxia, has informed the hypothesis that abnormal neurovascular coupling (NVC) may be the neurobiological origin of ME/CFS. NVC is a critical process for normal brain function, in which glutamate from an active neuron stimulates Ca(2+) influx in adjacent neurons and astrocytes. …”
Publicado 2022
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304259por Berger, Matthew N, Taba, Melody, Marino, Jennifer L, Lim, Megan S C, Skinner, S Rachel“…In total, 2 researchers extracted data and performed quality assessments independently using the Newcastle-Ottawa Scale for quantitative articles and the Critical Appraisal Skills Programme for qualitative articles. …”
Publicado 2022
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304260por Reyna, Myrtha E., Dai, Ruixue, Tran, Maxwell M., Breton, Vanessa, Medeleanu, Maria, Lou, Wendy Y. W., Foong, Rachel E., Emmerson, Melanie, Dharma, Christoffer, Miliku, Kozeta, Lefebvre, Diana L., Simons, Elinor, Azad, Meghan B., Chan-Yeung, Moira, Becker, Allan B., Mandhane, Piush J., Turvey, Stuart E., Hall, Graham L., Moraes, Theo J., Sears, Malcolm R., Subbarao, Padmaja“…IMPORTANCE: Despite advances in asthma therapeutics, the burden remains highest in preschool children; therefore, it is critical to identify primary care tools that distinguish preschool children at high risk for burdensome disease for further evaluation. …”
Publicado 2022
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