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304401por Do, Victor, Buchanan, Francine, Gill, Peter, Nicholas, David, Wahi, Gita, Bismilla, Zia, Coffey, Maitreya, Zhou, Kim, Bayliss, Ann, Selliah, Presanna, Sappleton, Karen, Mahant, Sanjay“…Further, understanding lived experience is critical to advancing efforts to address these well-known health disparities. …”
Publicado 2023
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304402“…It is a high-risk procedure since it is infrequently performed, but it is time-sensitive and critical for survival when needed.1,2 Time-sensitive procedural skills such as EC are subject to relatively rapid decay,3,4 and unlike other high-risk procedures, in which just-in-time training (JITT) may improve real time procedural performance, the extreme time sensitivity of cricothryotomy precludes JITT as a feasible educational intervention to improve EC performance.5 As such, clinicians must periodically review the essential concepts and practice the physical actions of the procedure in order to build and maintain familiarity with the steps involved and to develop and maintain the muscle memory necessary to perform it quickly and confidently. …”
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304403por Tarver, Emily M, Jefferson, Gina D, Parker, Patrick, Readman, Kristina, Marocho, Susana M Salazar, Lerant, Anna A“…Demonstrate additional critical actions in the management of a patient with a TIAF, including early consultation with otolaryngology and cardiothoracic surgery as well as emergent blood transfusion and activation of a massive transfusion protocol. …”
Publicado 2021
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304404por Boyle, Tehnaz, Boggs, Krislyn, Gao, Jingya, McMahon, Maureen, Bedenbaugh, Rachel, Schmidt, Lauren, Zachrison, Kori Sauser, Goralnick, Eric, Biddinger, Paul, Camargo Jr, Carlos A“…Forty (24%) hospitals and EDs lacked access to burn specialists; toxicologists, 30 (18%); radiation specialists, 25 (15%); and trauma specialists, 20 (12%). Among critical access hospitals (CAHs) or EDs with <10,000 annual visits (n=36), 92% received routine nondisaster telehealth services but lacked toxicologist (25%), burn (22%), and radiation (17%) specialist access. …”
Publicado 2023
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304405por Cascalheira, Cory J, Flinn, Ryan E, Zhao, Yuxuan, Klooster, Dannie, Laprade, Danica, Hamdi, Shah Muhammad, Scheer, Jillian R, Gonzalez, Alejandra, Lund, Emily M, Gomez, Ivan N, Saha, Koustuv, De Choudhury, Munmun“…Technology-delivered interventions are beginning to incorporate machine learning (ML) and natural language processing (NLP) to automate intervention components and tailor intervention content. A critical step in using ML and NLP in technology-delivered interventions is demonstrating how accurately these methods model clinical constructs. …”
Publicado 2023
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304406“…IMPORTANCE: Increasing mortality from suicide, drug overdose, and alcohol-related liver disease (collectively referred to as deaths of despair) is a critical public health crisis. Income inequality and social mobility have been separately associated with all-cause mortality; however, no studies have examined their interaction with these preventable deaths. …”
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304407“…Monitoring T cells, especially CD8 subset changes, has important implications for diagnosing and treating mild and severe patients being critically ill.…”
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304408por Wang, Tianyuan, Gao, Xiangrui, Huai, Zhe, Gong, Zhaohui, Mao, Ting, Fan, Xuezhe, Wu, Xingxing, Duan, Zhiyuan, Wang, Xiaodong, Du, Jiewen, Yao, Mengcheng, Li, Xin, Wu, Min, Wang, Zonghu, Zhang, Lin, Zhang, Junjie, Cao, Wenbo, Yan, Kai, Fang, Yujie, Ma, Shixiang, Yang, Kun, Wu, Lili, An, Frank, Yang, Yi, Lai, Lipeng, Huang, Xiaolu“…Antibody discovery is one of the most critical steps that determine the crucial properties of antibody drugs, such as efficacy, safety, and developability. …”
Publicado 2023
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304409por Mir, Mohd Salim, Singh, Parmeet, Bhat, Tauseef A., Kanth, Raihana H., Nazir, Aijaz, Al-Ashkar, Ibrahim, Kamran, Muhammad, Hadifa, Adel A., El Sabagh, Ayman“…Therefore, adoption of efficient weed management practice is critical for the success and widespread adoption of direct seeded rice. …”
Publicado 2023
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304410por Jameel, Muhammad Azhar, Nadeem, Muhammad Sajid, Haq, Shiekh Marifatul, Mubeen, Iqra, Shabbir, Arifa, Aslam, Shahzad, Ahmad, Riyaz, Gaafar, Abdel-Rhman Z., Al-Munqedhi, Bander M. A., Bussmann, Rainer W.“…SIMPLE SUMMARY: Given the potential impact of climate change on the distributions of endemic species, it is critical to implement species recovery and habitat management measures to protect threatened species. …”
Publicado 2023
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304411Mutational Analysis of Circulating Omicron SARS-CoV-2 Lineages in the Al-Baha Region of Saudi Arabiapor Almalki, Shaia S R, Izhari, Mohammad Asrar, Alyahyawi, Hanan E, Alatawi, Saleha Keder, Klufah, Faisal, Ahmed, Waled A M, Alharbi, Raed“…Twelve crucial RBD mutations: D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, and Y505H were identified except the lineage BA.5.2/22B in which F486V mutation was not observed. Critical deletions S106 in membrane protein NSP6, E31in nucleocapsid, and L24 in spike region were observed in all the lineages. …”
Publicado 2023
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304412por Fossum, Bradley, Hollenbeck, Justin, Whalen, Ryan, Garcia, Alexander, Foster, Michael, Provencher, Matthew, Ganokroj, Phob“…OBJECTIVES: Segmental medial meniscus allograft transplantation (MAT) has been shown to restore knee biomechanics, however, stable fixation of the transplant is critical to avoid extrusion and maximize healing. The purpose of this study was to evaluate the degree of meniscal extrusion and biomechanical function of segmental MAT performed with meniscocapsular sutures versus repair augmentation with knotless suture anchors. …”
Publicado 2023
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304413por Atzmon, Ran, Chang, Wenteh, Vel, Monica, Safran, Marc, Chu, Constance, Abrams, Geoff, Sherman, Seth“…Preserving chondrocyte viability while ensuring the correct size and contour of the MACI membrane is critical to the outcome. Traditional manual preparation has been performed using scissors (Sc). …”
Publicado 2023
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304414por Kopp, Marcel A, Meisel, Christian, Liebscher, Thomas, Watzlawick, Ralf, Cinelli, Paolo, Schweizerhof, Oliver, Blex, Christian, Lübstorf, Tom, Prilipp, Erik, Niedeggen, Andreas, Druschel, Claudia, Schaser, Klaus-Dieter, Wanner, Guido A, Curt, Armin, Lindemann, Gertraut, Nugeva, Natalia, Fehlings, Michael G, Vajkoczy, Peter, Cabraja, Mario, Dengler, Julius, Ertel, Wolfgang, Ekkernkamp, Axel, Rehahn, Kerstin, Martus, Peter, Volk, Hans-Dieter, Unterwalder, Nadine, Kölsch, Uwe, Brommer, Benedikt, Hellmann, Rick C, Baumgartner, Elias, Hirt, Julian, Geurtz, Laura-Christin, Saidy, Ramin Raul Ossami, Prüss, Harald, Laginha, Ines, Failli, Vieri, Grittner, Ulrike, Dirnagl, Ulrich, Schwab, Jan M“…The primary outcome was quantitative monocytic Human Leukocyte Antigen-DR expression (mHLA-DR, synonym MHC II), a validated marker for immune suppression in critically ill patients associated with infection susceptibility. mHLA-DR was assessed from Day 1 to 10 weeks after injury by applying standardized flow cytometry procedures. …”
Publicado 2023
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304415por Van Der Heide, M Y C, Verstraelen, T E, Van Lint, F H M, Bosman, L P, De Brouwer, R, Proost, V M, Germans, T, Dickhoff, C, Schoonderwoerd, B A, Houweling, A C, Gimeno-Blanes, J R, De Boer, R A, Cox, M G P J, Van Tintelen, P, Wilde, A A M“…While the risk model has proven to be valid, two main points of criticisms remain to be discussed: first, the risk model is only validated at baseline and second, appropriate ICD therapy and sustained ventricular tachycardia (VT) <250 bpm is an imperfect surrogate outcome for SCD. …”
Publicado 2023
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304416por Anker, Markus S., Lena, Alessia, Roeland, Eric J., Porthun, Jan, Schmitz, Sebastian, Hadzibegovic, Sara, Sikorski, Philipp, Wilkenshoff, Ursula, Fröhlich, Ann‐Kathrin, Ramer, Luisa Valentina, Rose, Matthias, Eucker, Jan, Rassaf, Tienush, Totzeck, Matthias, Lehmann, Lorenz H., von Haehling, Stephan, Coats, Andrew J.S., Friede, Tim, Butler, Javed, Anker, Stefan D., Riess, Hanno, Landmesser, Ulf, Bullinger, Lars, Keller, Ulrich, Ahn, Johann“…BACKGROUND: Maintaining the ability to perform self‐care is a critical goal in patients with cancer. We assessed whether the patient‐reported ability to walk 4 m and wash oneself predict survival in patients with pre‐terminal cancer. …”
Publicado 2023
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304417por Dovel, Kathryn, Balakasi, Kelvin, Phiri, Khumbo, Shaba, Frackson, Offorjebe, Ogechukwu Agatha, Gupta, Sundeep K., Wong, Vincent, Lungu, Eric, Nichols, Brooke E., Masina, Tobias, Worku, Anteneh, Hoffman, Risa, Nyirenda, Mike“…BACKGROUND: HIV testing among the sexual partners of HIV–positive clients is critical for case identification and reduced transmission in southern and eastern Africa. …”
Publicado 2023
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304418por Schnaufer, Erica C.S., Barbosa, Marcelo S., Marques, Michele F.R., Brito, Gabriel T., Ferreira, Tiago S., Ribeiro, Anny D.C., Valiente, Anna C., Machado, Indianara R., Gonçalves, Crhistinne C.M., Tanaka, Tayana S.O., Guimarães, Monick L., Ribeiro, Suzana M., Croda, Julio, Simionatto, Simone“…The detection of drug-resistance mutations further emphasizes the critical need to expand diagnostic coverage, closely monitor treatment strategies, and maintain ongoing molecular surveillance. …”
Publicado 2023
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304419por Milambo, Jean Paul Muambangu, Ndirangu, James, Mangala, Samuel, Simba, Hannah, Kabego, Landry“…Outbreak investigation which is based on a critical assessment of core components of infection prevention and control (IPC) programs allows for the identification of different sources of exposure to the COVID-19 virus and for informing additional IPC recommendations. …”
Publicado 2023
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304420por Terrault, Norah, Monto, Alex, Stinchon, Michael R., Rusie, Erica, Moreo, Kathleen“…In response to questions regarding decisions about DAA therapy duration based on viral load, the panel engaged the audience in thinking critically about evidence-based cutoff values and natural fluctuations of HCV RNA concentrations. …”
Publicado 2015
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