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  1. 304541
    “…The ability to efficiently screen for modifiable risk factors associated with injury is critical in developing and implementing effective injury prevention programs. …”
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    Landing Error Scoring System (LESS) Items are Associated with the Incidence Rate of Lower Extremity Stress Fracture
  2. 304542
    “…We observed strong association of promoter hypermethylation of CDH1 with GC (OR = 12.23; 95% CI, 8.80–17.00; P = 1.42 × 10(−50)), suggesting that epigenetic regulation of CDH1 could play a critical role in the etiology of GC. Limitations of this study are as follows: we could not adjust for confounding factors; some meta-analyses were based on a small number of studies; sensitivity analysis was limited due to unavailability of data; we could not test publication bias for some meta-analyses due to small number of included studies. …”
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    Association of Genetic Variants in and Promoter Hypermethylation of CDH1 With Gastric Cancer: A Meta-Analysis
  3. 304543
    “…BACKGROUND: There is a critical need to expand the pool of available kidneys for African Americans who are on the transplant wait-list due to the disproportionally lower availability of deceased donor kidneys compared with other races/ethnic groups. …”
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    Patient-Centered mHealth Living Donor Transplant Education Program for African Americans: Development and Analysis
  4. 304544
    “…Additionally, the open-field assay revealed decreased exploration as well as decreased rearing in HA7 and OS-HA7 fed mice demonstrating a consistent pattern of increased anxiety-like behavior among these groups. Critically, behavior was not correlated with weight. …”
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    Resistant Starch Alters the Microbiota-Gut Brain Axis: Implications for Dietary Modulation of Behavior
  5. 304545
    “…Automation can add efficiency to remote monitoring, but patient acceptance of automated tools is critical for success. From 2010 to 2013, the Diabetes-Depression Care-management Adoption Trial (DCAT)–a quasi-experimental comparative effectiveness research trial aimed at accelerating the adoption of collaborative depression care in a safety-net health care system–tested a fully automated telephonic assessment (ATA) depression monitoring system serving low-income patients with diabetes. …”
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    Automated Remote Monitoring of Depression: Acceptance Among Low-Income Patients in Diabetes Disease Management
  6. 304546
    “…Sucrose transporters (SUTs) are critical for both phloem loading in source tissue and sucrose uptaking in sink tissue, and are considered to be the control points for regulating sucrose storage. …”
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    Structure, phylogeny, allelic haplotypes and expression of sucrose transporter gene families in Saccharum
  7. 304547
    “…Recently, inhibition of tumor angiogenesis has become a clinical anti-cancer strategy in line with chemotherapy, radiotherapy and surgery, which underscore the critical importance of the angiogenic switch during early tumor development. …”
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    Broad targeting of angiogenesis for cancer prevention and therapy
  8. 304548
    “…However, due to sample overlap and large age ranges of samples spanning multiple critical periods of brain maturation, more independent studies with samples within the window of time when psychotic symptoms have been shown to emerge (ages 17–26) are needed. …”
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    Atypical functional connectivity in resting-state networks of individuals with 22q11.2 deletion syndrome: associations with neurocognitive and psychiatric functioning
  9. 304549
    “…A constitutively active FoxM1 mutant lacking critical anaphase-promoting complex/cyclosome ([APC/C]-Cdh1) binding sites was used to evaluate ST3Gal1-mediated regulation of FoxM1 protein. …”
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    ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis
  10. 304550
    “…Important opportunities exist to improve the quality and coding of AKI data to better address critical knowledge gaps in AKI and improve care. METHODS: A modified Delphi consensus building process consisting of review of the literature and summary statements were developed through a series of alternating breakout and plenary sessions. …”
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    Optimizing administrative datasets to examine acute kidney injury in the era of big data: workgroup statement from the 15(th) ADQI Consensus Conference
  11. 304551
    “…Initial participants (also known as seeds) are a critical consideration in RDS because they begin the recruitment chains. …”
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    Including Online-Recruited Seeds: A Respondent-Driven Sample of Men Who Have Sex With Men
  12. 304552
    por Bennett, Milton J.
    Publicado 2016
    “…*The second exploration is a more critical view of our claims, seeking both supportive and contradictory theory and research regarding the value of diversity and/or the value of uniformity. …”
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    The value of cultural diversity: rhetoric and reality: Meeting Report on Fellows Day, International Academy of Intercultural Research 9th Biennial Congress, Bergen, Norway
  13. 304553
    “…AIMS: To critically evaluate the clinical implications of the use of non-fasting rather than fasting lipid profiles and to provide guidance for the laboratory reporting of abnormal non-fasting or fasting lipid profiles. …”
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    Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine
  14. 304554
    “…The primary endpoint was time to biochemical or clinical failure; the critical hazard ratio (HR) for non-inferiority was 1·208. …”
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    Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
  15. 304555
    por Duffy, Michael J
    Publicado 2010
    “…The aim of this article is to critically review the role of these biomarkers in screening normal-risk asymptomatic subjects for early cancer. …”
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    Use of Biomarkers in Screening for Cancer
  16. 304556
    “…Currently, licensed INSTIs include raltegravir (RAL), elvitegravir (EVG) and dolutegravir (DTG); these drugs have played a critical role in AIDS therapy, serving as additional weapons in the arsenal for treating patients infected with HIV-1. …”
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    Therapy-Emergent Drug Resistance to Integrase Strand Transfer Inhibitors in HIV-1 Patients: A Subgroup Meta-Analysis of Clinical Trials
  17. 304557
    “…Reducing maternal HIV prevalence and treating all maternal HIV infection early are critical for further progress.…”
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    Population–level effectiveness of PMTCT Option A on early mother–to–child (MTCT) transmission of HIV in South Africa: implications for eliminating MTCT
  18. 304558
    “…Vaccinia virus (dsDNA) cytoplasmic replication didn’t induce the redistribution of nuclear H2B-IFI16 or H2B into the cytoplasm. H2B is critical in KSHV and HSV-1 genome recognition by IFI16 during de novo infection. …”
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    Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses
  19. 304559
    “…Thus, the concomitant use of novel compounds represents a critical strategy to improve treatment results. Histone deacetylase inhibitors (HDACi) enhance the activity of several anticancer drugs including cisplatin and anti-Epidermal Growth Factor Receptor (anti-EGFR) compounds. …”
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    Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial
  20. 304560
    “…Online panels offer a second method of accessing this population, but they have been criticized for recruiting too few young adults, among whom e-cigarette use rates are highest. …”
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    Comparing Twitter and Online Panels for Survey Recruitment of E-Cigarette Users and Smokers
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