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304581por DeLoid, Glen M., Wang, Yanli, Kapronezai, Klara, Lorente, Laura Rubio, Zhang, Roujie, Pyrgiotakis, Georgios, Konduru, Nagarjun V., Ericsson, Maria, White, Jason C., De La Torre-Roche, Roberto, Xiao, Hang, McClements, David Julian, Demokritou, Philip“…The importance of food matrix and GIT effects on biointeractions was demonstrated, as well as the incorporation of these critical factors into a cellular toxicity screening model. …”
Publicado 2017
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304582por Huang, Chiun-Wei, Hsieh, Wen-Chuan, Hsu, Shih-Ting, Lin, Yi-Wen, Chung, Yi-Hsiu, Chang, Wen-Chi, Chiu, Han, Lin, Yun Han, Wu, Chung-Pu, Yen, Tzu-Chen, Huang, Feng-Ting“…Thus, the integrin α2β1 targeting (68)Ga-DOTA-A2B1 tracer was validated in NSCLC in contrast to accumulation of the clinically used (18)F-FDG PET tracer to see if (68)Ga-DOTA-A2B1-PET imaging can offer a valuable and critical diagnostic imaging criterion for the identification of phenotypes of aggressive lung cancer. …”
Publicado 2017
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304583“…CONCLUSIONS: This meta-analysis shows the critical roles of RNF213 p.R4810K in MMD especially familial MMD and ICASO in Japan, Korea, and China. …”
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304584por Phillips, Patrick P. J., Mendel, Carl M., Nunn, Andrew J., McHugh, Timothy D., Crook, Angela M., Hunt, Robert, Bateson, Anna, Gillespie, Stephen H.“…Culture methodology is critical to the primary trial outcome. Patients in clinical trials can have positive cultures after treatment ends that may not necessarily indicate relapse, which was ascribed previously to laboratory cross-contamination or breakdown of old lesions. …”
Publicado 2017
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304585por Lalas, Antonios, Nousias, Stavros, Kikidis, Dimitrios, Lalos, Aris, Arvanitis, Gerasimos, Sougles, Christos, Moustakas, Konstantinos, Votis, Konstantinos, Verbanck, Sylvia, Usmani, Omar, Tzovaras, Dimitrios“…In this context, computational fluid dynamics (CFD) simulations accompanied by fluid particle tracing (FPT) analysis of the inhaled ambient particles are deemed critical for lung function assessment. Also they enable the understanding of particle depositions on the airways of patients, since these accumulations may affect or lead to inflammations. …”
Publicado 2017
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304586por Harlow, Siobán D., Karvonen-Gutierrez, Carrie, Elliott, Michael R., Bondarenko, Irina, Avis, Nancy E., Bromberger, Joyce T., Brooks, Maria Mori, Miller, Janis M., Reed, Barbara D.“…Given that one-quarter of midlife women were highly or moderately symptomatic across all domains in the pre-menopause, addressing symptom burden in early midlife is likely critical to ameliorating risk in the most vulnerable populations. …”
Publicado 2017
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304587por Siassakos, D, Jackson, S, Gleeson, K, Chebsey, C, Ellis, A, Storey, C, Heazell, Alex, Draycott, Tim, Winter, Cathy, Hillman, Jemima, Cox, Rachel, Lewis, Jacqui, Davey, Louise“…Diagnosis: Stillbirth is an emergency for parents but not always for staff; communication can seem cold; well‐designed bereavement space is critical. Birth: Staff shift priorities to mother and future, but for parents their baby is still a baby; parents are not comfortable with staff recommending vaginal birth as the norm; there are several reasons why parents ask for a caesarean; better care involves clear communication, normal behaviour, and discussion of coping strategies. …”
Publicado 2017
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304588“…Given patient-centered care has been found to positively impact patient health outcomes, it is critical to provide formal education on patient-centered EHR communication skills. …”
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304589por Robbins, Reuben N, Gouse, Hetta, Brown, Henry G, Ehlers, Andries, Scott, Travis M, Leu, Cheng-Shiun, Remien, Robert H, Mellins, Claude A, Joska, John A“…Without accurate, clinically useful, and relatively brief NCI screening tests that can be administered by all levels of clinical staff, critical opportunities to provide psychoeducation, behavioral planning, additional ART adherence support, and adjuvant therapies for NCI (when they become available) are missed. …”
Publicado 2018
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304590“…BACKGROUND: Assessing outcomes of habitat management is critical for informing and adapting conservation plans. …”
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304591por Obrist, Daniel, Kirk, Jane L., Zhang, Lei, Sunderland, Elsie M., Jiskra, Martin, Selin, Noelle E.“…Estimates of gaseous Hg(0) emissions to the atmosphere over land, long considered a critical Hg source, have been revised downward, and most terrestrial environments now are considered net sinks of atmospheric Hg due to substantial Hg uptake by plants. …”
Publicado 2018
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304592“…Participants were defined as child, parent, paediatric or pediatric and the context as intensive or critical care. Papers were excluded where activity reflected ‘participants’ as research subjects. …”
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304593por Smith, Harriet, Horobin, Adele, Fackrell, Kathryn, Colley, Veronica, Thacker, Brian, Hall, Deborah A.“…Part of this project uses a consensus methodology (‘Delphi’ survey), whereby all relevant stakeholders identify important and critical outcome domains from a long list of candidates. …”
Publicado 2018
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304594por Yin, Xiang, Feng, Liangshu, Ma, Di, Yin, Ping, Wang, Xinyu, Hou, Shuai, Hao, Yulei, Zhang, Jingdian, Xin, Meiying, Feng, Jiachun“…Astrocytic Cx43, hemichannels, and GJIC play critical roles in OGD/R injury-induced neuroinflammatory responses; treatment differentially targeting astrocytic Cx43, hemichannels, and GJIC may provide novel avenues for therapeutics during cerebral I/R injury. …”
Publicado 2018
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304595por Ilzarbe, Daniel, de la Serna, Elena, Baeza, Inmaculada, Pariente, Jose, Fortea, Adriana, Redondo, Marina, Bargallo, Nuria, Castro-Fornieles, Josefina, Sugranyes, Gisela“…A linear mixed model was built using Stata IC 13.1 to evaluate the effect of group and time on CTH and SA, including hemisphere as fixed effects and correcting by total intracranial volume and setting a critical p-value of .05. RESULTS: Thirty-nine subjects completed the follow-up. …”
Publicado 2018
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304596por Klauser, Paul, Xin, Lijing, Fournier, Margot, Griffa, Alessandra, Cleusix, Martine, Jenni, Raoul, Cuenod, Michel, Gruetter, Rolf, Hagmann, Patric, Conus, Philippe, Baumann, Philipp, Do, Kim Q“…A recent study in early psychosis from our group, did not report significant improvement in negative symptoms (potentially linked to the modest baseline levels) but showed improvement in cognition (i.e. processing speed) and an increase in the brain antioxidant glutathione (GSH) levels, indicating good target engagement.1 Indeed, research in animal models highlights the critical role of redox regulation by brain GSH for white matter maturation and maintenance. …”
Publicado 2018
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304597por Cotel, Marie-Caroline, Polacek, Romana, Lenartowicz, Ewelina, Natesan, Sridhar, Cooper, Jonathan, Vernon, Anthony“…To fully harness the potential of novel immunomodulatory therapeutics, it is critical to first determine the impact of antipsychotics on microglial function in vivo. …”
Publicado 2018
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304598por Dey, Avyarthana, Javadzadeh, Alborz, Sabesan, Priyadharshini, Radua, Joaquim, Theberge, Jean, Palaniyappan, Lena“…Examining the state of GSH deficit in schizophrenia is a critical step when attempting to correct putative redox imbalance in this illness using agents such as N-Acetyl Cysteine (NAC). …”
Publicado 2018
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304599por Almodóvar, Carmen, Guardiola, Maria, Salgado-Pineda, Pilar, Moreno, Marcos, Gallego, Carme, Prats, Claudia, Arias, Barbara, Pomarol-Clotet, Edith, McKenna, Peter J, Fatjó-Vilas, Mar“…BACKGROUND: Alterations of synaptic plasticity are currently accepted to play a critical role in schizophrenia (SZ). Among genes of neuronal plasticity there is Neuritin1 gene (NRN1), which has been associated with SZ, age at onset and differences in general cognitive performance in this disorder. …”
Publicado 2018
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304600por Zhang, TianHong, Li, HuiJun, Tang, YingYing, Li, Chunbo, Woodberry, Kristen, Shapiro, Daniel I, Niznikiewicz, Margaret, Shenton, Martha E, Keshavan, Matcheri S, Stone, William S, Wang, Jijun“…Dr. Seidman provide a critical step in the implementation of CHR concept in China, just as an obvious need and urgency for prevention and early intervention for Chinese patients with schizophrenia.…”
Publicado 2018
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