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  1. 304641
    “…BACKGROUND: Excellent adherence to tuberculosis (TB) treatment is critical to cure TB and avoid the emergence of resistance. …”
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    Wirelessly observed therapy compared to directly observed therapy to confirm and support tuberculosis treatment adherence: A randomized controlled trial
  2. 304642
    por Wang, Xiao-Zhen, Li, Wen-Xue
    Publicado 2019
    “…The correlation of the expression of miR-145, TNF-α, IL-6, and IL-10 with Kellgren-Lawrence (K-L) grades was assessed by Spearman correlation analysis. The critical levels of miR-145, TNF-α, IL-6, and IL-10 in distinguishing different K-L grades were determined by receiver operating characteristic (ROC) curve analysis. …”
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    Changes of serum inflammatory factors and miR-145 expression in patients with osteoarthritis before and after treatment and their clinical value
  3. 304643
    “…Delineate key behaviors critical to multidisciplinary team success Identify optimal strategies for communicating in multidisciplinary teams. …”
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    2527 Mount Sinai health hackathon: Harnessing the power of collaboration to advance experiential team science education
  4. 304644
    “…A patient was considered a transfer patient if they were transferred to a separate general hospital, children’s hospital, federal health care facility, rehabilitation facility, Critical Access Hospital or psychiatric hospital. Chi-square tests and t-tests were used for descriptive statistics. …”
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    3455 Association between Transfer of Children from the Emergency Department and Pediatric Readiness of the Hospital
  5. 304645
    “…American Journal of Respiratory and Critical Care Medicine 2017 (in press).…”
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    2298: Allergic asthma is associated with elevated sphingolipid levels in children
  6. 304646
    por Freundlich, Robert Edward
    Publicado 2019
    “…Understanding the risk factors for reintubation after cardiac surgery and identifying effective interventions to reduce these reintubations is of critical importance to optimize patient outcomes. High-flow nasal cannula (HFNC) provides up to 60 liters per minute of 100% oxygen, dead space washout, and humidification to improve secretion clearance, and has shown some benefits in improving hypoxia and reducing reintubation in select populations. …”
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    3081 Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients with High Flow Nasal Cannula
  7. 304647
    “…Moreover, they felt the need to teach themselves many critical skills through trial and error. This has led to perceptions that they cannot compete effectively with PhDs and MD-PhD scientists for research funding and positions. …”
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    3292 Duke Integrated Physician-Scientist Development
  8. 304648
    “…DISCUSSION/SIGNIFICANCE OF IMPACT: HCC is the second leading cause of cancer-related death worldwide and therapeutic options are limited for patients who are not surgical candidates. T-cells are a critical component of the anti-tumor response to HCC. …”
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    3236 Identification of exhaustive markers in cytotoxic T-cells to guide immune modulation in hepatocellular carcinoma ex vivo
  9. 304649
    “…Therefore, more research needs to be done to determine the critical time period within which this medicine will be effective if given to patients. …”
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    3204 Renin-Angiotensin System Inhibitors Do Not Improve Survival in Fibrillin-1 Hypomorphic Mice with Established Aortic Aneurysm
  10. 304650
    “…We sought to determine whether these differences in CRRs translated into reductions in health resource utilization (HRU) in this population of critically ill, hospitalized patients. METHODS: The microbiological intent-to-treat population included 116 patients (71 EXE, 45 SoC) with documented S. aureus who received a single 2-hour infusion of blinded study drug dosed based on target attainment. …”
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    LB3. Exebacase (EXE) Reduced Length of Stay and 30-Day Readmission Rates for US Patients with Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia Including Endocarditis Compared with Standard of Care Antibiotics (SoC) Alone in a Phase 2 Study
  11. 304651
    “…Supportive supervision, change management, and timely resolution of technology-related issues were critical implementation considerations to ensure adherence to the intervention. …”
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    mHealth intervention “ImTeCHO” to improve delivery of maternal, neonatal, and child care services—A cluster-randomized trial in tribal areas of Gujarat, India
  12. 304652
    “…OBJECTIVE: The objective of this study was to develop survey questions addressing aggregate and partner-specific group sex behaviors to measure prevalence of GSEs and associated risks in persons participating in Project Diagnostic Evaluation To Expand Critical Testing Technologies (DETECT), including MSM seeking HIV and STD testing at a public clinic in Seattle, Washington. …”
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    Group Sex Events Among Cisgender Men Who Have Sex With Men: Cross-Sectional and Longitudinal Survey Study to Explore Participation and Risk-Taking Behaviors
  13. 304653
    “…However, signals obtained from ECG versus wearable photoplethysmography (PPG) devices are different, and a critical first step preceding their widespread use is to determine whether HRV metrics derived from PPG devices also relate to older adults’ physical function. …”
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    Associations Between Heart Rate Variability Measured With a Wrist-Worn Sensor and Older Adults’ Physical Function: Observational Study
  14. 304654
    “…Objective: The surgical technique, safety, efficacy, and clinical application value of the intra-neuroendoscopic technique (INET) for the treatment of subacute-chronic and chronic septal subdural hematoma was investigated based on the structure and pathological features of the hematoma wall, and the critical factors of hematoma growth and recurrence were determined, in order to provide reference for clinical drug treatment. …”
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    A Clinical Study of the Intra-Neuroendoscopic Technique for the Treatment of Subacute-Chronic and Chronic Septal Subdural Hematoma
  15. 304655
    “…Understanding how perturbations in metabolism are related to AD is critical to identifying novel targets for disease-modifying therapies. …”
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    Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study
  16. 304656
    “…Given that pyroptosis has played a critical role in the progression of non-alcoholic steatohepatitis (NASH), here, we investigated whether the regulation of pyroptosis activation is responsible for the protective role of monounsaturated oleic acids in the context of hepatocellular lipotoxicity. …”
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    Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
  17. 304657
    “…IMPORTANCE: Prompt recognition of myocardial infarction symptoms is critical for timely access to lifesaving emergency cardiac care. …”
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    Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States
  18. 304658
    “…BACKGROUND: Critically ill patients frequently develop muscle atrophy and weakness in the intensive‐care‐unit setting [intensive care unit‐acquired weakness (ICUAW)]. …”
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    Serum amyloid A1 mediates myotube atrophy via Toll‐like receptors
  19. 304659
    “…Pre-implantation development is a critical period of developmental plasticity, which could have long-lasting effects on offspring growth and health. …”
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    The impact of selected embryo culture conditions on ART treatment cycle outcomes: a UK national study
  20. 304660
    “…BACKGROUND: Affective states, including sentiment and emotion, are critical determinants of health. However, few studies among men who have sex with men (MSM) have examined sentiment and emotion specifically using real-time social media technologies. …”
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    Associations Between Affective States and Sexual and Health Status Among Men Who Have Sex With Men in China: Exploratory Study Using Social Media Data
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