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  1. 304781
    “…BACKGROUND: Coronavirus disease 2019 (COVID-19) is currently the critical health problem of the globe, including Ethiopia. …”
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    Knowledge, attitude, and preventive practices towards COVID-19 and associated factors among adult hospital visitors in South Gondar Zone Hospitals, Northwest Ethiopia
  2. 304782
    “…We therefore have carried on relevant collation, analysis, investigation and criticism to Mongolian local knowledge on plants in MAKK, and obtained the status quo of these local knowledge. …”
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    A historical and ethnobotanical study on local botanical knowledge recorded in the book “Mongolia and Amdo and the Dead City of Khara-Khoto”
  3. 304783
    “…Sialic acid-binding immunoglobulin-type lectin-G (Siglec-G) is a CD33-related receptor highly expressed in B-1a cells to serve critical immunoregulatory functions. In sepsis, B-1a cell numbers in PerC are decreased. …”
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    Extracellular CIRP decreases Siglec-G expression on B-1a cells skewing them towards a pro-inflammatory phenotype in sepsis
  4. 304784
    “…METHODS: We conducted a critical synthesis from a systematic review of the literature. …”
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    Intervenciones para la salud mental de estudiantes universitarios durante la pandemia por COVID-19: una síntesis crítica de la literatura
  5. 304785
    “…We characterized the effects of brain astroglia on spinal cord inflammation, focusing on astroglial connexin (Cx)43, because we recently reported that Cx43 has a critical role in regulating neuroinflammation. METHODS: Because glutamate aspartate transporter (GLAST)(+) astroglia are enriched in the brain gray matter, we generated Cx43(fl/fl);GLAST-CreER(T2/+) mice that were brain gray matter astroglia-specific Cx43 conditional knockouts (Cx43 icKO). …”
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    Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination
  6. 304786
    “…CONCLUSION: Vitamin D deficiency in patients with COVID-19 is correlated with an increased risk of hospital admission and the need for critical care. We found no clear relationship between vitamin D levels and mortality.…”
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    The relationship between 25(OH) vitamin D levels and COVID-19 onset and disease course in Spanish patients
  7. 304787
    “…Our finding further confirmed the critical role of nsp14-ExoN in CoV life cycle, suggesting that it may be a target for the design of universal anti-CoV drugs. …”
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    Crucial mutation in the exoribonuclease domain of nsp14 of PEDV leads to high genetic instability during viral replication
  8. 304788
    “…Previous research has revealed that the gas exchange-mediated respiratory drive in critically ill dairy cattle with low O(2) saturation induces panting. …”
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    Involvement of the VEGF signaling pathway in immunosuppression and hypoxia stress: analysis of mRNA expression in lymphocytes mediating panting in Jersey cattle under heat stress
  9. 304789
    “…BACKGROUND: Several factors like altitude, age, sex, pregnancy, socioeconomic status, life style and race influence hematological reference interval (RIs), which are critical to support clinical decisions and to interpret laboratory data in research. …”
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    Umbilical cord blood hematological parameters reference interval for newborns from Addis Ababa, Ethiopia
  10. 304790
    “…The study highlights high heterogeneity in CTC enumeration and EMP gene expression between tumour-bearing mice and within individual blood samples, and therefore caution should be taken when interpreting pooled CTC analyses. Critically, tumour cells were present in the epithelial-mesenchymal hybrid state in the circulation. …”
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    Diversity of Epithelial-Mesenchymal Phenotypes in Circulating Tumour Cells from Prostate Cancer Patient-Derived Xenograft Models
  11. 304791
    “…OBJECTIVE: Our objective was to systematically identify and review the cost of illness (COI) of MS in LMICs to critically appraise the methodologies used, compare cost estimates across countries and by level of disease severity, and examine cost drivers. …”
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    Economic Burden of Multiple Sclerosis in Low- and Middle‐Income Countries: A Systematic Review
  12. 304792
    “…More importantly, we highlight the critical role of these differential alternative splicing events in poor prognosis, and we believe in the potential for their further translation into targets for immunotherapy. …”
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    Alternative splicing associated with cancer stemness in kidney renal clear cell carcinoma
  13. 304793
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    Respiratory Physiology of Prone Positioning With and Without Inhaled Nitric Oxide Across the Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Severity Spectrum
  14. 304794
    “…BACKGROUND: The aspects of marriage and relationship and their effect on couples’ satisfaction are essential and critical aspects to be explored in this globalized and contemporary world. …”
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    Improved couple satisfaction and communication with marriage and relationship programs: are there gender differences?—a systematic review and meta-analysis
  15. 304795
    “…Larvae farming conditions, such as temperature, pH, and moisture, have been critically examined. However, the substrate carbon to nitrogen ratio (C/N), one of the key parameters that may affect larval survival and bioconversion efficiency, is significantly less studied. …”
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    Effects of Different Nitrogen Sources and Ratios to Carbon on Larval Development and Bioconversion Efficiency in Food Waste Treatment by Black Soldier Fly Larvae (Hermetia illucens)
  16. 304796
    “…An anti-CCR2 monoclonal antibody (αCCR2), was used to block the CCR2 axis in a protocol that partially eliminates monocytes from the circulation at the time of anti-PD-L1 antibody (αPD-L1) injection, and for the critical period of their recruitment into the brain following treatment. …”
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    Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathy
  17. 304797
    “…We used the Joanna Briggs Institute Critical Appraisal tools to assess the quality of included articles. …”
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    Predictors of mortality in patients with drug-resistant tuberculosis: A systematic review and meta-analysis
  18. 304798
    “…OBJECTIVES: To determine unique factors associated with CVD in PWH and to assess CAD by coronary computed tomography angiography (CTA) and critical pathways of arterial inflammation and immune activation. …”
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    Assessment of Coronary Artery Disease With Computed Tomography Angiography and Inflammatory and Immune Activation Biomarkers Among Adults With HIV Eligible for Primary Cardiovascular Prevention
  19. 304799
    “…AIMS/HYPOTHESIS: Adipocytes are critical cornerstones of energy metabolism. While obesity-induced adipocyte dysfunction is associated with insulin resistance and systemic metabolic disturbances, adipogenesis, the formation of new adipocytes and healthy adipose tissue expansion are associated with metabolic benefits. …”
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    HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling
  20. 304800
    “…However, it is acceptability as a method of collection and screening by women is critical and yet unknown. A breast health questionnaire was disseminated to women through breast cancer charities, patient support groups and social media platforms, with the aim of collecting opinions on the acceptability of use of NAF as a potential screening tool. …”
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    Breast health screening: a UK-wide questionnaire
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