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304801por Gupta, Rishi K, Rosenheim, Joshua, Bell, Lucy C, Chandran, Aneesh, Guerra-Assuncao, Jose A, Pollara, Gabriele, Whelan, Matthew, Artico, Jessica, Joy, George, Kurdi, Hibba, Altmann, Daniel M, Boyton, Rosemary J, Maini, Mala K, McKnight, Aine, Lambourne, Jonathan, Cutino-Moguel, Teresa, Manisty, Charlotte, Treibel, Thomas A, Moon, James C, Chain, Benjamin M, Noursadeghi, Mahdad“…BACKGROUND: We hypothesised that host-response biomarkers of viral infections might contribute to early identification of individuals infected with SARS-CoV-2, which is critical to breaking the chains of transmission. We aimed to evaluate the diagnostic accuracy of existing candidate whole-blood transcriptomic signatures for viral infection to predict positivity of nasopharyngeal SARS-CoV-2 PCR testing. …”
Publicado 2021
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304802por Mascheroni, Alessandro, Choe, Eun Kyoung, Luo, Yuhan, Marazza, Michele, Ferlito, Clara, Caverzasio, Serena, Mezzanotte, Francesco, Kaelin-Lang, Alain, Faraci, Francesca, Puiatti, Alessandro, Ratti, Pietro Luca“…This information would critically guide the adaptation of antiparkinsonian medications and nonpharmacological interventions. …”
Publicado 2021
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304803“…Although she was given methylprednisolone which can suppress ACTH for up to 48 hours, ACTH deficiency is the most critical endocrine dysfunction and is present in nearly 70% of cases of pituitary apoplexy. …”
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304804por Kazemi, Maryam, Pierson, Roger A, Parry, Stephen A, Kaviani, Mojtaba, Chilibeck, Philip D“…PCOS cohorts have a tendency for increased total and trunk lean tissue mass likely attributed to obesity. However, most critically, whether PCOS influences other lean tissue areas (appendicular), morphology, and function is unclear. …”
Publicado 2021
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304805por Vogt, Annabelle, Sadeghlar, Farsaneh, Ayub, Tiyasha H., Schneider, Carlo, Möhring, Christian, Zhou, Taotao, Mahn, Robert, Bartels, Alexandra, Praktiknjo, Michael, Kornek, Miroslaw T., Toma, Marieta, Schmidt-Wolf, Ingo G. H., Branchi, Vittorio, Matthaei, Hanno, Kalff, Jörg C., Strassburg, Christian P., Gonzalez-Carmona, Maria A.“…The co-stimulation with CD40Ligand (CD40L) is critical in the maturation of DC and T-cell priming. …”
Publicado 2021
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304806por Anand, Shuchi, Montez-Rath, Maria, Han, Jialin, Cadden, LinaCel, Hunsader, Patti, Kerschmann, Russell, Beyer, Paul, Boyd, Scott D., Garcia, Pablo, Dittrich, Mary, Block, Geoffrey A., Parsonnet, Julie, Chertow, Glenn M.“…Vaccine introduction to younger individuals, those living in neighborhoods with a large population of racial/ethnic minority residents, and those living in low-income neighborhoods may be critical to disrupting the spread of infection.…”
Publicado 2021
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304807por Bayen, Eleonore, Nickels, Shirley, Xiong, Glen, Jacquemot, Julien, Subramaniam, Raghav, Agrawal, Pulkit, Hemraj, Raheema, Bayen, Alexandre, Miller, Bruce L, Netscher, George“…BACKGROUND: Lying on the floor for a long period of time has been described as a critical determinant of prognosis following a fall. …”
Publicado 2021
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304808por Mukhopadhyay, Rupak, Arora, Narendra Kumar, Sharma, Pradeep Kumar, Dalpath, Suresh, Limbu, Priya, Kataria, Geetanjali, Singh, Rakesh Kumar, Poluru, Ramesh, Malik, Yogesh, Khera, Ajay, Prabhakar, P. K., Kumar, Saket, Gupta, Rakesh, Chellani, Harish, Aggarwal, Kailash Chander, Gupta, Ratan, Arya, Sugandha, Aboubaker, Samira, Bahl, Rajiv, Nisar, Yasir Bin, Qazi, Shamim Ahmad“…Referral to a hospital was refused by 126 (84%); 119 had clinical severe infection (CSI), one 0–6 days old had fast breathing and six had critical illness (CI). Of 119 CSI cases managed on outpatient injection gentamicin and oral amoxicillin, 116 (96.7%) recovered, 55 (45.8%) received all seven gentamicin injections and only one died. …”
Publicado 2021
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304809por Giede-Jeppe, Antje, Sprügel, Maximilian I., Huttner, Hagen B., Borutta, Matthias, Kuramatsu, Joji B., Hoelter, Philip, Engelhorn, Tobias, Schwab, Stefan, Koehn, Julia“…INTRODUCTION: Although automated pupillometry is increasingly used in critical care settings, predictive value of automatically assessed pupillary parameters during different intracranial pressure (ICP) levels and possible clinical implications are unestablished. …”
Publicado 2020
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304810“…It is well known that ‘marker density’ is a critical factor that affects the accuracy of GP, however, how to properly measure ‘marker density’ in GP is yet to be determined. …”
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304811por Bamodu, Oluwaseun Adebayo, Tzou, Kai-Yi, Lin, Chia-Da, Hu, Su-Wei, Wang, Yuan-Hung, Wu, Wen-Ling, Chen, Kuan-Chou, Wu, Chia-Chang“…ABSTRACT: Background: Testosterone plays a critical role in prostate development and pathology. …”
Publicado 2021
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304812por Sivaraj, Dharshan, Padmanabhan, Jagannath, Henn, Dominic, Magbual, Noah J., Andrikopoulos, Sophia L., Chen, Kellen, Januszyk, Michael, Gurtner, Geoffrey C.“…CONCLUSION: Our results highlight the important role of IQGAP1 as a critical early stage mediator of mechanotransduction pathways contributing to the development of FBR. …”
Publicado 2021
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304813por Liu, Qiao, Dong, Taiwei, Xi, Miaomiao, Gou, Licheng, Bai, Yang, Hou, Lian, Li, Min, Ou, Li, Miao, Feng, Wei, Peifeng“…With the AMSTAR 2 standard, the methodological quality assessment found that 9 studies were rated low quality and 6 studies were rated critically low quality. Based on the results of the systematic review, the GRADE system recommended ranking method was used to evaluate the quality of evidence and the recommendation level. …”
Publicado 2021
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304814“…The young men also criticized the campaign for making a link between sperm quality and masculinity. …”
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304815“…The case described shows that milder forms of coronavirus infection may lead to other types of critical and unusual thrombotic complications. An otherwise healthy 47-year-old Caucasian woman developed fever and respiratory signs and symptoms consistent with a possible case of COVID-19 infection in late March of 2020. …”
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304816por Mitchell, William Beau, Davila, Jennifer G., Keenan, Janine, Jackson, Jenai, Tal, Adit, Morrone, Kerry A, Silver, Ellen J, O'Brien, Sarah H., Manwani, Deepa“…There were 28 (52%) patients in this cohort with severe and critical illness, as based on established criteria, and 25 (46%) patients required increased ventilatory support. …”
Publicado 2020
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304817por Nel, Isabelle, Beaudoin, Lucie, Gouda, Zouriatou, Rousseau, Camille, Soulard, Pauline, Rouland, Matthieu, Bertrand, Léo, Boitard, Christian, Larger, Etienne, Lehuen, AgnèsEnlace del recurso
Publicado 2021
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304818“…BACKGROUND: Increasing evidence has demonstrated the critical roles of mRNA modification regulators on multiple types of cancers. …”
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304819por Xiao, Ting, Wei, Yuli, Cui, Mengqi, Li, Xiaohe, Ruan, Hao, Zhang, Liang, Bao, Jiali, Ren, Shanfa, Gao, Dandi, Wang, Ming, Sun, Ronghao, Li, Mingjiang, Lin, Jianping, Li, Dongmei, Yang, Cheng, Zhou, Honggang“…Novel coronavirus infection can cause severe inflammation and even sequelae of pulmonary fibrosis in critically ill patients. We hope to find a drug that can not only inhibit virus replication but also alleviate inflammation and pulmonary fibrosis in patients. …”
Publicado 2021
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304820por Quaresima, Virginia, Scarpazza, Cristina, Sottini, Alessandra, Fiorini, Chiara, Signorini, Simona, Delmonte, Ottavia Maria, Signorini, Liana, Quiros-Roldan, Eugenia, Imberti, Luisa“…Although males spent more days in the hospital, had a longer disease duration, developed a critical illness more frequently, and were admitted and died in the ICU more than females, the total rate of deaths among patients was not significantly different between sexes. …”
Publicado 2021
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