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304901por Roberts, Kathryn J., Smith, Colette, Cluver, Lucie, Toska, Elona, Zhou, Siyanai, Boyes, Mark, Sherr, Lorraine“…These findings address a critical evidence gap, highlighting the commonality of mental health burden within the context of adolescent motherhood and HIV within South Africa as well as the urgent need for support and further research to ensure effective evidence-based programming is made available for this group. …”
Publicado 2021
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304902por Wang, Yi, Zhu, Gui-Qi, Tian, Di, Zhou, Chang-Wu, Li, Na, Feng, Ying, Zeng, Meng-Su“…CONCLUSION: Our study revealed that the interplay between m6A modification and lncRNAs might have critical role in predicting GC prognosis, sculpting TIME landscape and predicting the responses to ICIs therapy. …”
Publicado 2022
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304903por Hasheminasab, Seyed Sajjad, Conejeros, Iván, D. Velásquez, Zahady, Borggrefe, Tilman, Gärtner, Ulrich, Kamena, Faustin, Taubert, Anja, Hermosilla, Carlos“…Significant reduction of C. parvum-induced suicidal NETosis was measured after PMN treatments with purinergic receptor P2X1 inhibitor NF449, under both oxygen circumstances, this receptor was found to play a critical role in the induction of NETs, indicating its importance. …”
Publicado 2022
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304904por Poncette, Akira-Sebastian, Mosch, Lina Katharina, Stablo, Lars, Spies, Claudia, Schieler, Monique, Weber-Carstens, Steffen, Feufel, Markus A, Balzer, Felix“…BACKGROUND: Continuous monitoring of vital signs is critical for ensuring patient safety in intensive care units (ICUs) and is becoming increasingly relevant in general wards. …”
Publicado 2022
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304905por Gao, Wei, Wang, Yulu, Xiong, Ye, Sun, Liya, Wang, Lu, Wang, Kun, Lu, Henry Y., Bao, Aihua, Turvey, Stuart E., Li, Qiang, Yang, Hong“…Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a life-threatening condition of critically-ill patients, characterized by overwhelming inflammatory responses in the lung. …”
Publicado 2019
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304906por Costentin, Charlotte, Piñero, Federico, Degroote, Helena, Notarpaolo, Andrea, Boin, Ilka F., Boudjema, Karim, Baccaro, Cinzia, Podestá, Luis G., Bachellier, Philippe, Ettorre, Giuseppe Maria, Poniachik, Jaime, Muscari, Fabrice, Dibenedetto, Fabrizio, Duque, Sergio Hoyos, Salame, Ephrem, Cillo, Umberto, Marciano, Sebastian, Vanlemmens, Claire, Fagiuoli, Stefano, Burra, Patrizia, Van Vlierberghe, Hans, Cherqui, Daniel, Lai, Quirino, Silva, Marcelo, Rubinstein, Fernando, Duvoux, Christophe“…LAY SUMMARY: Considering discrepancies between pre-LT tumour assessment and explant are frequent, reassessing the risk of recurrence after LT is critical to further refine the management of patients with HCC. …”
Publicado 2022
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304907por Cadiz, Mika P., Jensen, Tanner D., Sens, Jonathon P., Zhu, Kuixi, Song, Won-Min, Zhang, Bin, Ebbert, Mark, Chang, Rui, Fryer, John D.“…BACKGROUND: Microglia, the resident immune cells of the brain, play a critical role in numerous diseases, but are a minority cell type and difficult to genetically manipulate in vivo with viral vectors and other approaches. …”
Publicado 2022
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304908por Tse, Angel, Xavier, Sabatinie, Trollope-Kumar, Karen, Agarwal, Gina, Lokker, Cynthia“…Ultimately, system changes to allow more efficient and appropriate levels of care for patients with EDs, removing the burden from family medicine, are critical as EDs are on the rise. PLAIN ENGLISH SUMMARY: A person with an eating disorder will normally seek care from their family physician first. …”
Publicado 2022
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304909por Tekin, Aysun, Qamar, Shahraz, Singh, Romil, Bansal, Vikas, Sharma, Mayank, LeMahieu, Allison M, Hanson, Andrew C, Schulte, Phillip J, Bogojevic, Marija, Deo, Neha, Zec, Simon, Valencia Morales, Diana J, Belden, Katherine A, Heavner, Smith F, Kaufman, Margit, Cheruku, Sreekanth, Danesh, Valerie C, Banner-Goodspeed, Valerie M, St Hill, Catherine A, Christie, Amy B, Khan, Syed A, Retford, Lynn, Boman, Karen, Kumar, Vishakha K, O'Horo, John C, Domecq, Juan Pablo, Walkey, Allan J, Gajic, Ognjen, Kashyap, Rahul, Surani, Salim“…METHODS: In this observational analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study: COVID-19 Registry cohort, the latitudes and altitudes of hospitals were examined as a covariate for mortality within 28 d of admission and the length of hospital stay. …”
Publicado 2022
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304910por Gu, Kui, Song, Zengxu, Zhou, Changyu, Ma, Peng, Li, Chao, Lu, Qizhong, Liao, Ziwei, Huang, Zheren, Tang, Yizhi, Li, Hao, Zhao, Yu, Yan, Wenjun, Lei, Changwei, Wang, Hongning“…Prevention of zoonotic infectious disease and controlling the risk of transmission of S. Enteriditidis critically requires the evolution of rapid and sensitive detection methods. …”
Publicado 2022
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304911por Fletcher, Benjamin R., Damery, Sarah, Aiyegbusi, Olalekan Lee, Anderson, Nicola, Calvert, Melanie, Cockwell, Paul, Ferguson, James, Horton, Mike, Paap, Muirne C. S., Sidey-Gibbons, Chris, Slade, Anita, Turner, Neil, Kyte, Derek“…Methodological quality of included studies was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data, and an exploration of publication bias performed. …”
Publicado 2022
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304912“…[Image: see text] Photocatalytic CO(2) reduction is a critical objective in the field of artificial photosynthesis because it can potentially make a total solution for global warming and shortage of energy and carbon resources. …”
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304913por Wondmeneh, Temesgen Gebeyehu“…Identifying the magnitude of dietary diversity and its influencing factors among pregnant women in the pastoral region of Afar, where no study has been conducted, is critical for establishing an intervention program in the region. …”
Publicado 2022
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304914por Rosa, Nicolas, Ivanova, Hristina, Wagner, Larry E., Kale, Justin, La Rovere, Rita, Welkenhuyzen, Kirsten, Louros, Nikolaos, Karamanou, Spyridoula, Shabardina, Victoria, Lemmens, Irma, Vandermarliere, Elien, Hamada, Kozo, Ando, Hideaki, Rousseau, Frederic, Schymkowitz, Joost, Tavernier, Jan, Mikoshiba, Katsuhiko, Economou, Anastassios, Andrews, David W., Parys, Jan B., Yule, David I., Bultynck, Geert“…Via in silico superposition, we previously found that the residue K87 of Bcl-xL spatially resembled K17 of Bcl-2, a residue critical for Bcl-2’s IP(3)R-inhibitory properties. …”
Publicado 2021
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304915por Wilairatana, Polrat, Mala, Wanida, Milanez, Giovanni De Jesus, Masangkay, Frederick Ramirez, Kotepui, Kwuntida Uthaisar, Kotepui, Manas“…The quality of the included studies was assessed using critical appraisal tools from the Joanna Briggs Institute. …”
Publicado 2022
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304916por Li, Wen-Yang, Wang, Daqing, Guo, Yuhao, Huang, Hong, Zhao, Hongwen, Kang, Jian, Wang, Wei“…The optimal discriminant models are: y(1) (postponed viral shedding time) = − 0.244 + 0.2829x(1) (the interval from the onset of symptoms to antiviral treatment) + 0.2306x(4) (age) + 0.234x(28) (Urea) − 0.2847x(34) (Dual-antiviral therapy) + 0.3084x(38) (Treatment with antibiotics) + 0.3025x(21) (Treatment with Methylprednisolone); y(2) (disease progression) = − 0.348–0.099x(2) (interval from Jan 1st,2020 to individualized onset of symptoms) + 0.0945x(4) (age) + 0.1176x(5) (imaging characteristics) + 0.0398x(8) (short-term exposure to Wuhan) − 0.1646x(19) (lymphocyte counts) + 0.0914x(20) (Neutrophil counts) + 0.1254x(21) (Neutrphil/lymphocyte ratio) + 0.1397x(22) (C-Reactive Protein) + 0.0814x(23) (Procalcitonin) + 0.1294x(24) (Lactic dehydrogenase) + 0.1099x(29) (Creatine kinase).The output ≥ 0 predicted postponed viral shedding time or disease progressing to severe/critical state. These two models yielded the maximum AUROC and faired best in terms of prognostic performance (sensitivity of78.6%, 75%, and specificity of 66.7%, 88.9% for prediction of postponed viral shedding time and disease severity, respectively). …”
Publicado 2022
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304917por Carvalho, Kepler, de Cesar Netto, Cesar, Mansur, Nacime S., Lalevée, Matthieu, Lintz, Francois, Buedts, Kristian, Goldberg, Andrew J., Deland, Jonathan T., Femino, John E., Anderson, Donald D., Walt, Jennifer S., Dibbern, Kevin N.“…CATEGORY: Hindfoot; Midfoot/Forefoot INTRODUCTION/PURPOSE: Peritalar subluxation (PTS) of the hindfoot is a critical finding in Progressive Collapsing Foot Deformity (PCFD). …”
Publicado 2022
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304918“…Determining whether these genetic variations of P. falciparum are linked to DHA-PPQ resistance is critical, especially along the China–Myanmar (CM) border, where PPQ has been utilized for decades. …”
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304919por Hallenbeck, Haijing Wu, Jaworski, Beth K, Wielgosz, Joseph, Kuhn, Eric, Ramsey, Kelly M, Taylor, Katherine, Juhasz, Katherine, McGee-Vincent, Pearl, Mackintosh, Margaret-Anne, Owen, Jason E“…Research to evaluate new features and capabilities in these apps is critical but lags behind app development. The initial release of PTSD Coach, a free self-management app developed by the US Departments of Veterans Affairs and Defense, was found to have a positive public health impact. …”
Publicado 2022
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304920por Kuroda, Masaru, Tamiya, Eiji, Nose, Takahisa, Ogimoto, Akiyoshi, Taura, Junki, Imamura, Yuki, Fukuzawa, Masayuki, Hayashi, Takuya, Akao, Masaharu, Yamashita, Takeshi, Lip, Gregory Y. H., Okumura, Ken“…Patients with AF aged 80 years or older who were not considered candidates for standard-dose OACs were included in the study; reasons these patients could not take standard-dose OACs included low creatinine clearance (<30 mL per minute), low body weight (≤45 kg), history of bleeding from critical organs, continuous use of nonsteroidal anti-inflammatory drugs, or concomitant use of antiplatelet drugs. …”
Publicado 2022
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