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  1. 305101
    “…BACKGROUND: Herein, the effect of pre-use of Dexmedetomidine(Dex) on the half-effective dose (ED50) and 95%-effective dose (ED95) of Remimazolam tosilate(RT) in inhibiting the positive cardiovascular response(CR) which means blood pressure or heart rate rises above a critical threshold induced by double-lumen bronchial intubation was evaluated. …”
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    Effect of pre-use of Dexmedetomidine on the effective inhibitory dose of remimazolam tosilate on positive cardiovascular response in double-lumen endobronchial intubation: a clinical study
  2. 305102
    “…Recently, numerous evidence indicated that CXCL3 is broadly expressed in various human tumor types, and it is also known to play a critical role in mediating tumor development and progression. …”
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    Elevated expression of CXCL3 in colon cancer promotes malignant behaviors of tumor cells in an ERK-dependent manner
  3. 305103
    “…OBJECTIVES: To determine if lopinavir/ritonavir +/- hydroxychloroquine will reduce the proportion of participants who survive without requiring ventilatory support, 15 days after enrolment, in adult participants with non-critically ill SARS-CoV-2 infection. TRIAL DESIGN: ASCOT is an investigator-initiated, multi-centre, open-label, randomised controlled trial. …”
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    The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial
  4. 305104
    “…CONCLUSIONS: MIS-C seems to be the most frequent presentation among critically ill children with SARS-CoV-2 infection. MIS-C patients are older and usually healthy. …”
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    Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain
  5. 305105
    “…METHODS: We enrolled 98 COVID-19 patients with varying disease severity (3 asymptomatic, 53 mild, 34 moderate, 5 severe, 3 critical) and 78 non-COVID-19 controls matched for gender and co-morbidities. …”
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    Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity
  6. 305106
    “…With a steady increase in older adults with amputations due to vascular conditions, it is critical to evaluate whether advanced prostheses can provide better safety and performance capabilities to maintain and improve quality of life in individuals who are predominantly designated MFCL level K2. …”
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    Using a microprocessor knee (C-Leg) with appropriate foot transitioned individuals with dysvascular transfemoral amputations to higher performance levels: a longitudinal randomized clinical trial
  7. 305107
    por Kishan, Amar U., Karnes, R. Jeffrey, Romero, Tahmineh, Wong, Jessica K., Motterle, Giovanni, Tosoian, Jeffrey J., Trock, Bruce J., Klein, Eric A., Stish, Bradley J., Dess, Robert T., Spratt, Daniel E., Pilar, Avinash, Reddy, Chandana, Levin-Epstein, Rebecca, Wedde, Trude B., Lilleby, Wolfgang A., Fiano, Ryan, Merrick, Gregory S., Stock, Richard G., Demanes, D. Jeffrey, Moran, Brian J., Braccioforte, Michelle, Huland, Hartwig, Tran, Phuoc T., Martin, Santiago, Martínez-Monge, Rafael, Krauss, Daniel J., Abu-Isa, Eyad I., Alam, Ridwan, Schwen, Zeyad, Chang, Albert J., Pisansky, Thomas M., Choo, Richard, Song, Daniel Y., Greco, Stephen, Deville, Curtiland, McNutt, Todd, DeWeese, Theodore L., Ross, Ashley E., Ciezki, Jay P., Boutros, Paul C., Nickols, Nicholas G., Bhat, Prashant, Shabsovich, David, Juarez, Jesus E., Chong, Natalie, Kupelian, Patrick A., D’Amico, Anthony V., Rettig, Matthew B., Berlin, Alejandro, Tward, Jonathan D., Davis, Brian J., Reiter, Robert E., Steinberg, Michael L., Elashoff, David, Horwitz, Eric M., Tendulkar, Rahul D., Tilki, Derya
    Publicado 2021
    “…Optimal multimodality treatment is critical for improving outcomes in patients with high-risk prostate cancer.…”
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    Comparison of Multimodal Therapies and Outcomes Among Patients With High-Risk Prostate Cancer With Adverse Clinicopathologic Features
  8. 305108
    “…Emergency department (ED) visits due to serious health problems or accidents might pose critical life events for patients. This study aimed (a) to characterize older patients’ SRH and LS during the distinct event of an ED stay, and (b) to analyze concomitant associations of PROs with ED patients’ sociodemographic, disease-specific and care-related variables. …”
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    Self-reported health and life satisfaction in older emergency department patients: sociodemographic, disease-related and care-specific associated factors
  9. 305109
    “…CONCLUSION: Access to a bed net is a critical first step in the process of bed net utilization. …”
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    The role of ideation on the effect of an SBC intervention on consistent bed net use among caregivers of children under 5 years in Nigeria: a multilevel mediation analysis
  10. 305110
    “…Those issues include: (1) the need for early detection, intervention, prevention, and evidenced-based standards of care; (2) the critical need to make specialized care more accessible and affordable to all those in need; (3) the importance of developing uniform, evidenced-based standards of care; (4) the need for funding and conducting eating spectrum disorder research; and (5) the indispensability of advocacy, education, and legislation where these illnesses are concerned. …”
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    The legacy of hope summit: a consensus-based initiative and report on eating disorders in the U.S. and recommendations for the path forward
  11. 305111
    “…To assess quality, Joanna Briggs Critical Appraisal Tools was used. A Forest plot was used to present summary information on each article and pooled common effects. …”
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    The burden of household out-of-pocket healthcare expenditures in Ethiopia: a systematic review and meta-analysis
  12. 305112
    “…REVIEW FINDINGS: A total of 133 studies from 103 articles were included in this systematic review for data extraction and critical appraisal. Most studies were from North America (60%) and were conducted at 146 different hydropower dams/facilities. …”
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    How do changes in flow magnitude due to hydropower operations affect fish abundance and biomass in temperate regions? A systematic review
  13. 305113
    “…Detecting elevated amyloid-β (Aβ) pathology to support trial recruitment or initiating Aβ-targeting treatments would be of critical value. In this study, we aimed to examine the robustness of plasma biomarkers to detect elevated Aβ pathology at different stages of the AD continuum. …”
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    The accuracy and robustness of plasma biomarker models for amyloid PET positivity
  14. 305114
    “…Presence of cancer stem cells (CSCs) has been increasingly reported to be a critical contributing factor in drug resistance, tumor recurrence and metastasis. …”
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    MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway
  15. 305115
    “…Adverse clinical event outcomes included PE-related in-hospital deaths, critical systolic blood pressure consistently under 90 mmHg, refractory to volume loading and vasopressor infusion requirements, mechanical ventilation, and cardiopulmonary resuscitation. …”
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    Short-term prognostic value of clinical data in hospitalized patients with intermediate-risk acute pulmonary embolism
  16. 305116
    “…These small RNAs may have had an essential role in the process of spermatogenesis or may have critical roles in the post-fertilization development. …”
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    Qualitative and quantitative assessment of sperm miRNAs identifies hsa-miR-9-3p, hsa-miR-30b-5p and hsa-miR-122-5p as potential biomarkers of male infertility and sperm quality
  17. 305117
    “…BACKGROUND: Accessibility and utilization of postnatal newborn check-ups within 2 days after delivery are critical for a child’s survival, growth, and development. …”
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    Spatial distribution and determinants of newbornsnot receiving postnatal check-up withintwodays after birth in Ethiopia: a spatial and multilevel analysis of EDHS 2016
  18. 305118
    por Smith, Emily R., Oakley, Erin, Grandner, Gargi Wable, Rukundo, Gordon, Farooq, Fouzia, Ferguson, Kacey, Baumann, Sasha, Adams Waldorf, Kristina Maria, Afshar, Yalda, Ahlberg, Mia, Ahmadzia, Homa, Akelo, Victor, Aldrovandi, Grace, Bevilacqua, Elisa, Bracero, Nabal, Brandt, Justin S., Broutet, Natalie, Carrillo, Jorge, Conry, Jeanne, Cosmi, Erich, Crispi, Fatima, Crovetto, Francesca, del Mar Gil, Maria, Delgado-López, Camille, Divakar, Hema, Driscoll, Amanda J., Favre, Guillaume, Fernandez Buhigas, Irene, Flaherman, Valerie, Gale, Christopher, Godwin, Christine L., Gottlieb, Sami, Gratacós, Eduard, He, Siran, Hernandez, Olivia, Jones, Stephanie, Joshi, Sheetal, Kalafat, Erkan, Khagayi, Sammy, Knight, Marian, Kotloff, Karen L., Lanzone, Antonio, Laurita Longo, Valentina, Le Doare, Kirsty, Lees, Christoph, Litman, Ethan, Lokken, Erica M., Madhi, Shabir A., Magee, Laura A., Martinez-Portilla, Raigam Jafet, Metz, Torri D., Miller, Emily S., Money, Deborah, Moungmaithong, Sakita, Mullins, Edward, Nachega, Jean B., Nunes, Marta C., Onyango, Dickens, Panchaud, Alice, Poon, Liona C., Raiten, Daniel, Regan, Lesley, Sahota, Daljit, Sakowicz, Allie, Sanin-Blair, Jose, Stephansson, Olof, Temmerman, Marleen, Thorson, Anna, Thwin, Soe Soe, Tippett Barr, Beth A., Tolosa, Jorge E., Tug, Niyazi, Valencia-Prado, Miguel, Visentin, Silvia, von Dadelszen, Peter, Whitehead, Clare, Wood, Mollie, Yang, Huixia, Zavala, Rebecca, Tielsch, James M.
    Publicado 2023
    “…Prepregnancy obesity was also a risk factor for severe COVID-19 outcomes including intensive care unit admission (relative risk, 1.81; 95% confidence interval, 1.26–2.60), ventilation (relative risk, 2.05; 95% confidence interval, 1.20–3.51), any critical care (relative risk, 1.89; 95% confidence interval, 1.28–2.77), and pneumonia (relative risk, 1.66; 95% confidence interval, 1.18–2.33). …”
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    Clinical risk factors of adverse outcomes among women with COVID-19 in the pregnancy and postpartum period: a sequential, prospective meta-analysis
  19. 305119
    “…Impacts of the three factors, i.e., rating category, distribution skew, and task difficulty, on the indices were tested. RESULTS: The most criticized index, percent agreement (a(o)), showed as the most accurate predictor of reliability, reporting directional r(2) = .84. …”
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    Interrater reliability estimators tested against true interrater reliabilities
  20. 305120
    “…S3.3 INNATE IMMUNE RESPONSES TO PATHOGENIC FUNGI, SEPTEMBER 21, 2022, 4:45 PM - 6:15 PM:   OBJECTIVES: Up to 20% and 15% of critically ill influenza and coronavirus disease 2019 (COVID-19) patients are affected by influenza- and COVID-19-associated pulmonary aspergillosis (IAPA and CAPA) respectively. …”
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    S3.3d Influenza versus COVID-19-associated pulmonary aspergillosis: Profiling lower respiratory tract epithelial and myeloid innate immunity in patient samples
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