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  1. 305181
    “…Quality assessment of medical and economic literature was assured by application of general assessment standards for the systematic and critical appraisal of scientific studies. RESULTS: Vaccine efficacy in prevention of CIN 2 or higher lesions in HPV 16 or HPV 18 negative women, who received all vaccination doses, ranges between 98% and 100%. …”
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    Human papillomavirus (HPV) vaccination for the prevention of HPV 16/18 induced cervical cancer and its precursors
  2. 305182
    “…Hence, society's willingness-to-pay is the critical determinant in the question whether TNF-α-antagonists shall be reimbursed or not, or to define criteria for reimbursement. …”
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    Influence of tumor necrosis factor α in rheumatoid arthritis
  3. 305183
    “…Study selection and critical appraisal were conducted by two independent assessors. …”
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    Falls prevention for the elderly
  4. 305184
    “…The goal of regenerative medicine is to aid repair and regeneration of the lost tissues in parenchyma and airways for which mobilization of tissue-resident endogenous or bone marrow-derived exogenous stem cells niches is a critical step. We used a lung injury model in mice to identify and characterize functional lung stem cells to clarify how stem cell niches counteract this degenerative process. …”
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    Characterization of lung stem cell niches in a mouse model of bleomycin-induced fibrosis
  5. 305185
    “…A better understanding of the relationship between mitochondrial dysfunction in ASD and oxidative stress, along with other factors that may contribute to oxidative stress, will be critical to understanding how to guide treatment and management of ASD children. …”
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    Redox metabolism abnormalities in autistic children associated with mitochondrial disease
  6. 305186
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    Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care: The WikiTrauma Interrupted Time Series Protocol
  7. 305187
    “…Stakeholders’ nonmaterial desires, needs, and values often critically influence the success of conservation projects. …”
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    A protocol for eliciting nonmaterial values through a cultural ecosystem services frame
  8. 305188
    “…WHAT IS KNOWN ALREADY: The quality of the oocyte and maintenance of this quality during in vitro processing in the assisted reproductive technology (ART) laboratory is of critical importance to successful embryo development and a healthy live birth. …”
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    A spontaneous increase in intracellular Ca(2+) in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K(+) channels
  9. 305189
    “…This White Paper offers recommendations for the selection of state of-the-art metabolomics platforms and approaches that offer the widest biochemical coverage, considers critical sample collection and preservation, as well as standardization of measurements, among other important topics. …”
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    Metabolomics enables precision medicine: “A White Paper, Community Perspective”
  10. 305190
    “…Possible correlations between HRV parameters (mainly the standard deviation of all normal RR intervals, SDNN), clinical features (age, sex, type of MI, history of diabetes, left ventricle ejection fraction), angiographic characteristics (number of coronary arteries with critical stenoses, success and completeness of revascularization) and long-term outcomes were analysed. …”
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    Does heart rate variability correlate with long-term prognosis in myocardial infarction patients treated by early revascularization?
  11. 305191
    “…Strong uphill technique is critical to race performance since uphill segments are the most influential on race outcomes. …”
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    Factors that Influence the Performance of Elite Sprint Cross-Country Skiers
  12. 305192
    “…The test of the primary hypothesis (comparing groups on the proportion who are community ambulators at 16 weeks after randomisation) will be based on a one-sided 0.025-level hypothesis test using a procedure consisting of four interim analyses and one final analysis with critical values chosen by a Hwang-Shih-Decani alpha-spending function. …”
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    Improving community ambulation after hip fracture: protocol for a randomised, controlled trial
  13. 305193
    Publicado 2016
    “…INTERPRETATION: Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. …”
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    Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
  14. 305194
    “…Some of these programs have benefits beyond prevention of HIV—a critical consideration given that injection drug use is increasing across most United States demographic groups. …”
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    Estimation of the cost-effectiveness of HIV prevention portfolios for people who inject drugs in the United States: A model-based analysis
  15. 305195
    “…BACKGROUND: Acute kidney injury (AKI) is a severe disease in critically ill patients. Neutrophil infiltration into kidney was associated with the development of AKI, and P-selectin may be involved in the process of neutrophil recruitment in kidney. …”
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    Effect of Platelet-derived P-selectin on Neutrophil Recruitment in a Mouse Model of Sepsis-induced Acute Kidney Injury
  16. 305196
    “…OBJECTIVES: Legacy measures, such as the modified Harris Hip Score, have traditionally been utilized in the assessment of hip arthroscopy patients, but have been criticized for their application in this active patient population. …”
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    The Application of the Patient Reported Outcomes Information System (PROMIS) on Hip Arthroscopy Patients
  17. 305197
    “…Non-inferiority can be claimed for both reduced-dose and partial-breast radiotherapy, and was confirmed by the test against the critical HR being more than 2·03 (p=0·003 for the reduced-dose group and p=0·016 for the partial-breast group, compared with the whole-breast radiotherapy group). …”
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    Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial
  18. 305198
    “…The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained individuals on exercise performance and body composition. …”
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    International society of sports nutrition position stand: nutrient timing
  19. 305199
    Publicado 2017
    “…By providing estimates over a long time series, this study can monitor risk exposure trends critical to health surveillance and inform policy debates on the importance of addressing risks in context. …”
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    Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
  20. 305200
    “…Understanding how global perturbations in metabolism are related to severity of AD neuropathology and the eventual expression of AD symptoms in at-risk individuals is critical to developing effective disease-modifying treatments. …”
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    Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
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