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  1. 243761
    “…Phenotypic as well as the following key words were searched: targeted therapy; rapid identification; rapid; Gram positive; Gram negative; reduce(ed); cost(s); pneumoslide; PBP2; tube coagulase; matrix-assisted laser desorption/ionization time of flight; MALDI TOF; blood culture; EMR; electronic reporting; call to provider; collaboration; pharmacy; laboratory; bacteria; yeast; ICU; and others. …”
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    Effectiveness of Practices To Increase Timeliness of Providing Targeted Therapy for Inpatients with Bloodstream Infections: a Laboratory Medicine Best Practices Systematic Review and Meta-analysis
  2. 243762
    “…Dissociated cells from supraspinatus tissue of TT+DN versus sham mice were either analyzed by flow cytometry for PDGFRα and GFP expression at established postop time points or sorted and cultured for in vitro differentiation experiments to assess the fibroadipogenic potential of these cell populations. …”
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    PDGFRα+ Progenitor Cells Contribute to Muscle Fibroadipogensis Following Massive Rotator Cuff Tears in a Mouse Model
  3. 243763
    “…The chondrogenic differentiation of MDSCs following BMP2 delivery was assayed using cell culture. The mRNA expression of Aggrecan and Col2A were significantly higher in each BMP2 group compared to control or vehicle only (P<0.05). …”
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    Sustained Release of Bone Morphogenetic Protein 2 via Coacervate improves Muscle Derived Stem Cell Mediated Cartilage Regeneration in MIA-induced Osteoarthritis
  4. 243764
    “…Dysfunctions in DNA repair mechanisms, expressed as chromosome damage, were assessed in cultures with aphidicolin by the GEE test. RESULTS: Cytogenetic analyses were performed in 47 exposed individuals. …”
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    Persistence of Breakage in Specific Chromosome Bands 6 Years after Acute Exposure to Oil
  5. 243765
    “…The secreted cytokines and growth factors in cultured media were quantified using a Bio-Plex200 multiplex array system. …”
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    Overexpression of the miR-141/200c cluster promotes the migratory and invasive ability of triple-negative breast cancer cells through the activation of the FAK and PI3K/AKT signaling pathways by secreting VEGF-A
  6. 243766
    “…ChIP-seq studies using chromatin prepared from mouse lens and cultured lens cells demonstrate that Pax6-bound regions are mostly enriched with H3K4me2 and H3K4me1 in enhancers and promoters, though H3K4me3 marks only Pax6-containing promoters. …”
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    Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers
  7. 243767
    “…We found a strong narrative framework related to exemption seeking and a culture of distrust of government and medical institutions. …”
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    “Mommy Blogs” and the Vaccination Exemption Narrative: Results From A Machine-Learning Approach for Story Aggregation on Parenting Social Media Sites
  8. 243768
    “…Although further assessment is required, these data suggest that via ongoing cooperation in a culture of improved preparedness, an integrated military/civilian national trauma network has also positively impacted civilian results via reduced mortality in ISS ≥ 16 and reduced late inter-hospital transfers. …”
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    Potential benefits of an integrated military/civilian trauma system: experiences from two major regional conflicts
  9. 243769
    “…METHODS: HEPA 1–6 cells which could respectively overexpress TM6SF2 wild type and E167K variant were cultured and HEPA 1–6 cells with zero load plasmids were used as matched control. …”
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    E167K polymorphism of TM6SF2 gene affects cell cycle of hepatocellular carcinoma cell HEPA 1-6
  10. 243770
    “…METHODS: To better understand the role of modified PRs in breast cancer, we measured total and phospho-Ser294 PRs in 209 human breast tumors represented on 2754 individual tissue spots within a tissue microarray and assayed the regulation of this site in human tumor explants cultured ex vivo. To complement this analysis, we assayed PR target gene regulation in T47D luminal breast cancer models following treatment with progestin (promegestone; R5020) and antiprogestins (mifepristone, onapristone, or aglepristone) in conditions under which the receptor is regulated by Lys388 SUMOylation (K388 intact) or is SUMO-deficient (via K388R mutation to mimic persistent Ser294 phosphorylation). …”
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    Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs
  11. 243771
    “…Overall, low levels of reported risk were identified, and results illustrate important gaps in the understanding of risk among MSM across societies that could be addressed through culturally-tailored prevention messaging.…”
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    Perceptions of HIV Seriousness, Risk, and Threat Among Online Samples of HIV-Negative Men Who Have Sex With Men in Seven Countries
  12. 243772
    “…METHODS: A cross-sectional study among 520 teachers measured health literacy using the selfadministered, culturally adapted Sinhalese translation of Health Literacy Survey-European Union (HLS-EU). …”
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    Level of health literacy and factors associated with it among school teachers in an education zone in Colombo, Sri Lanka
  13. 243773
    “…METHODS: Allogenic MSCs were harvested from bone marrow and expanded in specific media (20% fetal bovine serum, 50 U ml(-1) penicillin, 50 mg ml(-1) streptomycin, 20 mg ml(-1) gentamicin, and 5 ng ml(-1) bFGF (fibroblast growth factor) in low glucose Dulbecco’s modified Eagle media) under standard cell culture conditions (37(o) C with 5% CO(2)). Surgery was carried out in 10 mature New Zealand white rabbits (8 months old). …”
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    Cartilage Repair with Mesenchymal Stem Cells (MSCs) Delivered in a Novel Chondroitin Sulfate / Polyethylene Glycol Hydrogel in a Rabbit Animal Model”
  14. 243774
    “…Second generation surgical technique was performed using autologous cultured chondrocytes (Vericel, Inc; Boston, MA) secured with a type I/III collagen bilayer membrane. …”
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    Second Generation Autologous Chondrocyte Implantation in the Patella: Improved Pain Relief and Functional Outcomes among U.S. Army Servicemembers
  15. 243775
    “…BACKGROUND: Daodi-herb is a part of Chinese culture, which has been naturally selected by traditional Chinese medicine clinical practice for many years. …”
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    Differences in chemical constituents of Artemisia annua L from different geographical regions in China
  16. 243776
    “…It also suggests that the research culture is slow to change in regard to how important and relevant treatment research questions are identified and prioritised. …”
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    Patients’, clinicians’ and the research communities’ priorities for treatment research: there is an important mismatch
  17. 243777
    “…The biggest challenge was in overcoming the differences in approach to lay co-researchers between NHS Trusts. Organisational culture has been slow to incorporate PPI and this has not yet been fully addressed. …”
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    A SHARED study-the benefits and costs of setting up a health research study involving lay co-researchers and how we overcame the challenges
  18. 243778
    “…FUNDING: Bill & Melinda Gates Foundation, Japan Ministry of Education, Science, Sports and Culture, Japan Ministry of Health, Labour and Welfare, AXA CR Fixed Income Fund and AXA Research Fund.…”
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    Population health and regional variations of disease burden in Japan, 1990–2015: a systematic subnational analysis for the Global Burden of Disease Study 2015
  19. 243779
    “…Here we demonstrate feasibility of Neurapheresis for MDR GBM and characterize system parameters for bacterial clearance. METHODS: PAK cultures were grown and diluted to 1 × 10(7) cells/mL in artificial CSF or Luria-Miller broth. …”
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    Feasibility of Neurapheresis™ as a Therapy for Multidrug Resistant Gram-negative Bacterial Meningitis
  20. 243780
    “…METHODS: In a multicenter prospective observational cohort study we collected surveillance cultures of nares, oropharynx, groin, perianal area, wounds, device site(s) and 10 environmental sites collected at enrollment, day 14, and every 30 days thereafter from 651 newly admitted patients. …”
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    Relatedness of MRSA and VRE Strains Isolated from Post-acute Care Patients and Their Environment: a Longitudinal Assessment
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