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  1. 244001
    “…MS-Hu6 showed the same level of "humanness" as human IgG1 in silico, and was non–immunogenic in ELISPOT assays for IL-2 and IFNγ in human peripheral blood mononuclear cell cultures. In conclusion, MS-Hu6 is efficacious, durable and manufacturable, and is therefore poised for future human testing as a multipurpose therapeutic for obesity, osteoporosis, and perhaps for AD.References: (1)Sun et al., Cell, 2006, PMID: 16630814; Ji et al, PNAS, 2018, PMID: 29440419; (3)Liu et al., Nature, 2017, PMID: 28538730; (4)Xiong et al., Nature (In press); (5)Gera et al., PNAS, 2020, PMID: 33127753 Presentation: Monday, June 13, 2022 12:30 p.m. - 2:30 p.m.…”
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    PMON51 A Single Multipurpose FSH–Blocking Therapeutic for Osteoporosis, Obesity and Alzheimer's Disease
  2. 244002
    “…The abundance of sterol regulatory element binding transcription factor 1 precursor (pSREBP1) and its mature fragment (nSREBP1) was upregulated by T09, but not LXRB overexpression. In the cells cultured with T09, knockdown of LXRB downregulated the abundance for pSREBP1 and nSREBP1. …”
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    The LXRB-SREBP1 network regulates lipogenic homeostasis by controlling the synthesis of polyunsaturated fatty acids in goat mammary epithelial cells
  3. 244003
    “…This cell line was used for characterization of [(18)F]FGln uptake and retention by transport analysis in cell culture and by PET/MRI (magnetic resonance imaging) in animal models. …”
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    PET/MR Imaging of a Lung Metastasis Model of Clear Cell Renal Cell Carcinoma with (2S,4R)-4-[(18)F]Fluoroglutamine
  4. 244004
    “…Experimental Design: Murine muscle myoblasts (C2C12) or primary murine muscle cultures were treated with PARP inhibitors (PJ34(10uM) or BYK204165(1uM)) or transfected with silencing RNA targeting PARP1. …”
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    OR07-5 PARP1 Contributes to the Glucocorticoid Receptor Transcriptional Response And Influences the Skeletal Muscle Phenotype
  5. 244005
    por Staccini, Pascal, Lau, Annie Y.S.
    Publicado 2022
    “…There is universal agreement on the necessity of a healthcare policy that addresses issues of gender, age, sexual orientation, and different cultures to ensure health equity for all, regardless of age or resources available. …”
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    Consuming Health Information and Vulnerable Populations: Factors of Engagement and Ongoing Usage
  6. 244006
    “…Only 37.9% of HAIs had documented positive microbiological culture result with gram negative bacteria including Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii and Citrobacter been the most common microorganisms and accounted for 40%–100% of the pathogens. …”
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    Healthcare-associated infections in Africa: a systematic review and meta-analysis of point prevalence studies
  7. 244007
    “…FujiLAM and AlereLAM urine assays, Xpert MTB/RIF Ultra assay on sputum or urine, sputum culture for Mycobacterium tuberculosis, and CD4 count were systematically carried out for all patients. …”
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    Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study
  8. 244008
    “…PBMCs from PWH on ART were cultured with or without gag-specific peptide stimulation and cytokine production was detected by flow cytometry. …”
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    2072. Of Mice and Men: HIV-induced CD38 expression on CD8+ T lymphocytes contributes to mitochondrial dysfunction and chronic inflammation despite antiretroviral therapy
  9. 244009
    “…Socioeconomic disparities need to be addressed, and equitable access to culturally sensitive comprehensive psychosocial assessments must be ensured. …”
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    Self-harm in children and adolescents by ethnic group: an observational cohort study from the Multicentre Study of Self-Harm in England
  10. 244010
    “…The expression of ADAR1, EV-D68 VP1, and HPIV3 hemagglutinin–neuraminidase (HN) proteins was identified using western blotting. The median tissue culture infectious dose (TCID(50)) was applied to detect viral titers. …”
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    ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway
  11. 244011
    “…Accepted SIBO diagnostic methods were both available breath tests (n-total = 15) and aspirate culture (n-total = 3). We found that among patients with non-alcoholic liver diseases, the random overall event rate of SIBO was 0.350 (95% CI, 0.244–0.472), p = 0.017. …”
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    The Prevalence of Small Intestinal Bacterial Overgrowth in Patients with Non-Alcoholic Liver Diseases: NAFLD, NASH, Fibrosis, Cirrhosis—A Systematic Review, Meta-Analysis and Meta-Regression
  12. 244012
    por Sella‐Weiss, Oshrat
    Publicado 2022
    “…Lastly, reduced food consumption during lunch might negatively impact overall nutrient intake, particularly in cultures where lunch is the main meal of the day. WHAT THIS PAPER ADDS: WHAT IS ALREADY KNOWN ON THE SUBJECT: Despite widespread agreement on the importance of STC, institutional care providers widely use NSTC. …”
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    What could go wrong? Non‐standardized versus standardized food texture classification
  13. 244013
    “…METHODS: The intervention is based on an initiative that was previously developed in Canada and then also pilot-tested in Lima, Peru, with the Center for Addiction and Mental Health (Ontario, Canada). The model will be culturally adapted with CESFAM PHC provider and user inputs to be relevant and valid to Chile. …”
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    Reducing stigma toward mental illness and substance use issues in primary health care in Chile: Protocol of a cluster controlled trial study
  14. 244014
    “…ATGL expression was determined by immunoblot and qRT-PCR, and the impact of ATGL function or protein knockdown, alone and in combination with BETi, was assessed by analyzing cell proliferation, mitochondrial function, and metabolic activity in TNBC and non-TNBC cells culture models. RESULTS: TNBC cells treated with two BETi markedly increased ATGL expression and lipolytic function and decreased intracellular lipid content in a dose and time-dependent manner. …”
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    BETi enhance ATGL expression and its lipase activity to exert their antitumoral effects in triple-negative breast cancer (TNBC) cells
  15. 244015
    “…In steps, the CD133 + /Lin-/CD45- cells were collected by fluorescence-activated cell sorting (FACS) labeled with CD133, Lin and CD45 antibodies, which were cultured and amplified in vitro. The biological features of CD133 + /Lin-/CD45- cells were studied in different aspects, including morphological trait observed with inverted microscope, ultrastructural characteristics observed under transmission electron microscope, expression of pluripotent markersidentified by immunofluorescent staining and Alkaline phosphatase staining. …”
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    Isolation of Swine Bone Marrow Lin-/CD45-/CD133 + Cells and Cardio-protective Effects of its Exosomes
  16. 244016
    “…Normal ovarian epithelial cell lines (HOSEpiC) and OC cell lines (OVCAR3、HEY、SKOV3) were cultured. Western blot was applied to analyze the expression of NUF2 in these cell lines. …”
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    NUF2 promotes tumorigenesis by interacting with HNRNPA2B1 via PI3K/AKT/mTOR pathway in ovarian cancer
  17. 244017
    “…In addition, we detected hAβ in conditioned medium from lens explant cultures prepared from Tg(+) mice, but not Tg(−) control mice, a finding consistent with constitutive hAβ generation in the lens. …”
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    Alzheimer’s disease amyloid-β pathology in the lens of the eye
  18. 244018
    “…The samples were initially tested for somatic cell counts (SCC) using Somatos mini(®) automatic cell counter. Culture and sensitivity testing was then carried out on any milk sample that had SCC ≥ 200,000 cells/mL. …”
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    The prevalence, antimicrobial sensitivity, and factors associated with camel mastitis in Isiolo County, Kenya
  19. 244019
    “…Environmental surface and hand hygiene were assessed using 3M™ Clean-Trace™ ATP test, 3M™ Petrifilm™ plates and bacteriological culture of Enterococcus species and E. coli. Cross contamination was assessed using results of antimicrobial susceptibility testing. …”
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    Improving infection control in a veterinary hospital: a detailed study on patterns of faecal contamination to inform changes in practice
  20. 244020
    “…METHODS: Prospective study of the antifungal sensitivity testing (natamycin, amphotericin B, voriconazole, itraconazole, fluconazole, posaconazole, caspofungin, micafungin) of fungal isolates from 50 cases of culture positive fungal keratitis by using E test method. …”
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    Evaluation of antifungal susceptibility and clinical characteristics in fungal keratitis in a tertiary care center in North India
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