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  1. 244041
    “…Cell Counting Kit-8 (CCK-8), colony formation assay, flow cytometry, immunofluorescence, wound healing assay, transwell assay, and tube-forming assay were used to detect the effect of genipin on hRMECs cultured in high glucose conditions. In vivo, streptozotocin (STZ) induced mice were used, and genipin was administered by intraocular injection (IOI). …”
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    Genipin relieves diabetic retinopathy by down-regulation of advanced glycation end products via the mitochondrial metabolism related signaling pathway
  2. 244042
    “…Tomiyama N. and co-workers (Oncol Lett 15:9929–9933, 2018) (Tomiyama, N) investigated the role of S100A16 in cancer stem cells using Yumoto cells (a CC cell line),The authors found upregulation of S100A16 in Yumoto cells following sphere formation as compared to monolayer culture.Despite a certain degree of understanding, the exact biological function of S100A16 in CC is still unclear. …”
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    Expression and gene regulatory network of S100A16 protein in cervical cancer cells based on data mining
  3. 244043
    “…In CURE ID database, clinical assessment was reported in 52% of published reports, with culture (bacterial/fungal) being the most reported (63%) diagnostic modality. …”
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    844. Landscape Analysis to Identify Effective Drug Repurposing Candidates for the Treatment of Implantation Mycoses: Comparison of World Health Organization Survey Treatment Data and Published Case Reports on CURE ID
  4. 244044
    “…RSV diagnosis was defined using positive test results (PCR, antigen, or culture) and ICD-10-CM diagnosis codes. Comorbidities were identified using diagnosis, procedure, and medication codes. …”
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    2634. All-Cause Hospitalization Following Outpatient Episodes for RSV Among Adults in the United States using an Integrated EHR-Claims Data Source
  5. 244045
    “…BACKGROUND: Whole genome sequencing (WGS) of bacterial pathogens directly from clinical samples or cultured isolates is a promising technique for diagnosing infections, yet challenges remain in using WGS to guide antimicrobial therapy. …”
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    966. Large-Scale Evaluation of AST Prediction using Resistance Marker Presence/Absence vs. Machine Learning on WGS Data
  6. 244046
    “…In 87 per cent of the animals showing a lobar pneumonia positive blood cultures were obtained. The pathological findings, judging from the early stages of the disease, are subject to considerable variation. …”
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    EXPERIMENTAL PNEUMONIA (FRIEDLÄNDER TYPE)
  7. 244047
    “…Results: Single exposure of cultured human dermal fibroblasts to UV-A(+BL) radiation yielded a very high increase in MMP-1 mRNA expression (11 ±1 fold expression for RT-PCR and 76 ±2 fold expression for real-time RT-PCR both at 30°C, 75 ±1 fold expression for real-time RT-PCR at 37°C) and a dose-dependent decrease in cell survival. …”
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    Water-filtered infrared-A radiation (wIRA) is not implicated in cellular degeneration of human skin
  8. 244048
    “…The levels of INF-r and IL-13 in the supernatants of the lymph node cell cultures stimulated with staphylococcal enterotoxin B (SEB) or ConA were increased in the Cy-treated mice, although the serum levels of total IgE were not. …”
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    A Role of Staphyococcus aureus, Interleukin-18, Nerve Growth Factor and Semaphorin 3A, an Axon Guidance Molecule, in Pathogenesis and Treatment of Atopic Dermatitis
  9. 244049
    “…This virus, which was first characterized following its isolation in cell culture in 1995, belongs to the family Orthomyxoviridae, genus, Isavirus. …”
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    Identification of the 3' and 5' terminal sequences of the 8 rna genome segments of european and north american genotypes of infectious salmon anemia virus (an orthomyxovirus) and evidence for quasispecies based on the non-coding sequences of transcripts
  10. 244050
    “…Enzymes can be purified from natural sources such as fungal cultures (e.g., Aspergillus niger, Cochliobolus carbonum, and Galerina marginata), or they can be made by expression of the encoding genes (obtained from the increasing number of microbial genome sequences) in hosts such as E. coli, Pichia pastoris, or a filamentous fungus such as T. reesei. …”
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    GENPLAT: an Automated Platform for Biomass Enzyme Discovery and Cocktail Optimization
  11. 244051
    “…The other two paraphyletic subclades include species that produce abundant stromata in which the large perithecia are immersed, large ascospores, and peculiar anamorphs that form pycnidia or sporodochia either on their natural substrate or in culture. In this study the evolution of species, morphology, and ecology of the three genera, Allantonectria, Nectria, and Pleonectria, are discussed based on the phylogenetic analyses. …”
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    A monograph of Allantonectria, Nectria, and Pleonectria (Nectriaceae, Hypocreales, Ascomycota) and their pycnidial, sporodochial, and synnematous anamorphs
  12. 244052
    “…Annexin V/propidium iodide staining followed by flow cytometric analysis was used to detect apoptosis in cell culture. Then gene expression profile of tumor cells treated with YM155 was analyzed with real-time PCR arrays. …”
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    Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells
  13. 244053
    “…This data would indicate that TEM8 is associated with the tumor vasculature rather than the tumor tissue, thus explaining the increased TEM8 expression in DLD-1 tumors compared to DLD-1 cell cultures. (89)Zr-df–L2mAb specifically targeted TEM8 in vitro and in vivo although the in vitro expression was not necessarily predictive of in vivo expression which seemed to be associated with the tumor vasculature. …”
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    Immuno-PET Imaging of Tumor Endothelial Marker 8 (TEM8)
  14. 244054
    “…Only seven trials reported clinical outcome data which limits our ability to make broad generalizations to different epidemiological settings and cultures. Cutaneous leishmaniasis One four‐arm RCT from Afghanistan compared indoor residual spraying (IRS), insecticide‐treated bednets (ITNs), and insecticide‐treated bedsheets, with no intervention. …”
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    Vector and reservoir control for preventing leishmaniasis
  15. 244055
    “…When we compared FDCs with single‐drug formulations we found little or no difference for sputum smear or culture conversion at the end of treatment (RR 0.99, 95% CI 0.96 to 1.02; 2319 participants, seven trials, high quality evidence), for serious adverse events (RR 1.45, 95% CI 0.90 to 2.33; 3388 participants, six trials, moderate quality evidence), and for adverse events that led to discontinuation of therapy (RR 0.96, 95% CI 0.56 to 1.66; 5530 participants, 13 trials, low quality evidence). …”
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    Fixed‐dose combinations of drugs versus single‐drug formulations for treating pulmonary tuberculosis
  16. 244056
    “…PARTICIPANTS/MATERIALS, SETTING, METHODS: Neonatal mouse gonads were developed in vitro, with tissue analysed at the end of the 4–6 day culture period, following immunofluorescence or hematoxylin and eosin staining. …”
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    Irinotecan metabolite SN38 results in germ cell loss in the testis but not in the ovary of prepubertal mice
  17. 244057
    “…Samples were also analyzed for selected processing-related parameters such as heat coagulation time (HCT), rennet coagulation time (RCT), rate of acid production by starter culture, alcohol stability, and activity of selected enzymes such as alkaline phosphatase activity, catalase activity, proteolytic activity, and lipase activity. …”
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    Comparison of Surti goat milk with cow and buffalo milk for physicochemical characteristics, selected processing-related parameters and activity of selected enzymes
  18. 244058
    “…Two damage models were introduced: 1) treatment with IL-1β (10ng/ml) at 48 hours before co-culture; or 2) controlled mechanical impaction (600 N within 2 ms). …”
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    Protective Effect of Normal Synovium on Damaged Cartilage
  19. 244059
    “…Implementation strategies addressed in the reviews were grouped into four categories – strategies targeting: 1. healthcare organisations (e.g. strategies to change organisational culture; 1 review); 2. healthcare workers by type of intervention (e.g. printed educational materials; 14 reviews); 3. healthcare workers to address a specific problem (e.g. unnecessary antibiotic prescription; 9 reviews); 4. healthcare recipients (e.g. medication adherence; 15 reviews). …”
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    Implementation strategies for health systems in low‐income countries: an overview of systematic reviews
  20. 244060
    “…METHODS AND FINDINGS: Colorectal and lymph node tissues, bone marrow, cerebral spinal fluid (CSF), plasma, and very large numbers of peripheral blood mononuclear cells (PBMCs) were obtained longitudinally from both participants and were studied for HIV persistence in several laboratories using molecular and culture-based detection methods, including a murine viral outgrowth assay (mVOA). …”
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    HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study
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