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26241“…Conclusion: Local and regional therapies remain a mainstay of curative and palliative treatment of patients with HCC. …”
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26242por Itami, Jun, Kobayashi, Kenya, Mori, Taisuke, Honma, Yoshitaka, Kubo, Yuko, Murakami, Naoya, Omura, Go, Okuma, Kae, Inaba, Koji, Takahashi, Kana, Kashihara, Tairo, Shimizu, Yuri, Takahashi, Ayaka, Nakayama, Yuko, Matsumoto, Fumihiko, Yoshimoto, Seiichi, Igaki, Hiroshi“…Materials and Methods: Between 2010 and 2018, 122 patients with HPV-related OPSCC in stages III and IV by the TNM classification 7th edition (TNM-7) were treated curatively at a single institution in Japan. The median age was 62.7 years. …”
Publicado 2022
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26243“…OBJECTIVE: To determine the clinical characteristics, management, and oncologic outcomes for patients with localized renal cell carcinoma (RCC) who develop ATR following curative-intent MIS for partial or radical nephrectomy. …”
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26244por Moziak, Kirsten, Picarda, Elodie, Perez, Natalia Muñoz, Galbo, Phillip, Zheng, Deyou, Zang, Xingxing, Martin, Allison“…BACKGROUND: There is currently no curative therapy for recurrent/refractory MB. Novel approaches to MB include immunotherapy, such as targeting the immune checkpoint molecule B7-H3. …”
Publicado 2022
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26245por Taylor, Jessica, Toker, Joseph, Masih, Katherine, Nathan, Erica, Terranova, Sabrina, Gilbertson, Richard“…Unfortunately, while curative, this treatment is associated with major, long-term, debilitating motor, developmental, and neuroendocrine side effects. …”
Publicado 2022
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26246por Leão, Inês, Garcia, Catarina, Antunes, Pedro, Campolargo, Ana, Dias, Isabel, Coimbra, Edite, Oliveira, Pedro, Zenha, Horácio, Costa, Horácio, Capela, Andreia, Viamonte, Sofia, Alves, Alberto J., Joaquim, Ana“…This prospective observational study (NCT04996147) aimed to analyse the acute impact of HNC curative multimodal treatment on health-related quality of life (HRQoL), nutritional status, physical and cognitive functions, and ET preferences. …”
Publicado 2022
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26247por La Barbera, Giorgia, Nommesen, Katrine Dalmo, Cuparencu, Catalina, Stanstrup, Jan, Dragsted, Lars Ove“…In this paper, we present a four-step approach used to compile and curate a database for the annotation of DNA adducts in biological samples. …”
Publicado 2022
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26248“…An analysis of the association between SLC6A8 and the tumor immune microenvironment (TIME) of LUAD was performed through the TISIDB database and estimation of stromal and immune cells in malignant tumor tissues using expression data (ESTIMATE) algorithm. Then, based on the curated list of SLC6A8-related immunomodulators, three genes (NT5E, CD40LG, CD80) were selected to construct SLC6A8-related immune signatures to further evaluate the immune aspect of LUAD prognosis. …”
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26249“…METHOD: To identify serum miRNAs that would be useful in screening multiple types of cancers, microarray cancer datasets were curated, yielding 13 different types of cancer with a total of 3352 cancer samples and 2809 non-cancer samples. …”
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26250“…METHODS: This is one of the first nutrition studies to apply content analysis techniques to TikTok, a social media app with over a billion active global users offering continuous streams of curated short-form videos. In August 2021, two independent coders downloaded the first-appearing 200 TikTok videos under the hashtag #mediterraneandiet. …”
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26251“…METHODS: Data were extracted using the NIH iSearch portfolio analysis platform to curate grant applications to the NIH and NHLBI. Keywords included nutrition or diet, followed by omics, metabolomics, lipidomics, proteomics, transcriptomics, genomics, and epigenomics. …”
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26252“…Atrial fibrillation (AF), a commonly seen cardiac disease without optimal curative treatment option, is usually treated by traditional Chinese medicine in China. …”
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26253por He, Beihui, Chen, Zheng, Nie, Yunmeng, Luo, Minmin, Xu, Sumei, Yan, Junbin, Chen, Zhiyun“…The hepatic pathology and biochemical indicators of rats were used to judge the modeling results and the curative effect of SQP. Western blotting and qRT–PCR were used to verify the expression of crucial target genes at the protein and RNA levels, respectively. …”
Publicado 2022
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26254“…Additional features of MRP include a curated search function, and filters that refine the topic-based pages and related resources to only those applicable to selected project inclusions and organizational unit. …”
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26255“…CONCLUSION: Through this study, we tried to evaluate the role of theaflavin-3,3’-digallate on multiple targets of SARS-CoV-2, and the positive in-silico results which were obtained on various pharmacodynamic and pharmacokinetic parameters, give a ray of hope as a potential therapeutic drug to this rapidly spreading disease. The search for a curative therapy for SARS-CoV-2 is still ongoing. The favourable preliminary results of TF3 through in-silico analysis offers a ray of hope in ending this devasting pandemic. …”
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26256por Lee, Dong-Hyun, Kim, Geun-Jeon, Kim, Hyun-Bum, Shin, Hyun-Il, Kim, Choung-Soo, Nam, Inn-Chul, Cho, Jung-Hae, Joo, Young-Hoon, Cho, Kwang-Jae, Sun, Dong-Il, Park, Young-Hak, Park, Jun-Ook“…We retrospectively reviewed the clinicopathological data of 418 patients diagnosed with squamous cell carcinomas of the oral cavity or oropharynx who underwent initial surgery (with curative intent) at our institute between 2010 and 2016. …”
Publicado 2022
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26257por Taiarol, Lorenzo, Bigogno, Chiara, Sesana, Silvia, Kravicz, Marcelo, Viale, Francesca, Pozzi, Eleonora, Monza, Laura, Carozzi, Valentina Alda, Meregalli, Cristina, Valtorta, Silvia, Moresco, Rosa Maria, Koch, Marcus, Barbugian, Federica, Russo, Laura, Dondio, Giulio, Steinkühler, Christian, Re, Francesca“…Currently, there are no curative treatments; therefore, the discovery of novel molecules with anti-tumor activity or suitable drug delivery systems are important research topics. …”
Publicado 2022
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26258por Shvetsov, Nikita, Grønnesby, Morten, Pedersen, Edvard, Møllersen, Kajsa, Busund, Lill-Tove Rasmussen, Schwienbacher, Ruth, Bongo, Lars Ailo, Kilvaer, Thomas Karsten“…However, to ensure success, AI often requires a time-consuming curation of data. In our approach, we repurposed AI pipelines and training data for cell segmentation and classification to identify tissue-infiltrating lymphocytes (TILs) in lung cancer tissue. …”
Publicado 2022
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26259por Sjöblom, Anni, Carpén, Timo, Stenman, Ulf-Håkan, Jouhi, Lauri, Haglund, Caj, Syrjänen, Stina, Mattila, Petri, Mäkitie, Antti, Hagström, Jaana“…Materials and methods: A total of 90 patients with OPSCC treated with curative intent at the Helsinki University Hospital (HUS), Helsinki, Finland, during 2012–2016 were included. …”
Publicado 2022
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26260por Cristofoletti, Cristina, Bresin, Antonella, Fioretti, Martina, Russo, Giandomenico, Narducci, Maria Grazia“…With the exception of allogenic transplantation, no curative chance is available to treat SS, and it is a priority to find new therapies that target SS cells within all disease compartments. …”
Publicado 2022
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