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26421por Lundström, Simon, Agger, Erik, Lydrup, Marie-Louise, Jörgren, Fredrik, Buchwald, Pamela“…METHODS: Patients who had undergone surgery for rectal cancer with curative intention between 2011 and 2014 were extracted from the Swedish Colorectal Cancer Registry. …”
Publicado 2023
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26422por Laetsch, Theodore W., Maude, Shannon L., Rives, Susana, Hiramatsu, Hidefumi, Bittencourt, Henrique, Bader, Peter, Baruchel, André, Boyer, Michael, De Moerloose, Barbara, Qayed, Muna, Buechner, Jochen, Pulsipher, Michael A., Myers, Gary Douglas, Stefanski, Heather E., Martin, Paul L., Nemecek, Eneida, Peters, Christina, Yanik, Gregory, Khaw, Seong Lin, Davis, Kara L., Krueger, Joerg, Balduzzi, Adriana, Boissel, Nicolas, Tiwari, Ranjan, O'Donovan, Darragh, Grupp, Stephan A.“…These findings demonstrate favorable long-term safety and suggest tisagenlecleucel as a curative treatment option for heavily pretreated pediatric and young adult patients with R/R B-ALL.…”
Publicado 2023
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26423por Alsalman, Mortadah, Alhamoud, Hassan, Alabdullah, Zainab, Alsleem, Raghad, Almarzooq, Zainab, Alsalem, Fatemah, Alsulaiman, Ahmed, Albeladi, Abdullah, Alsalman, Zaenb“…CONCLUSION: SCD is an inherited disease with economic, physical, and psychological burdens. However, curative options are costly, and hence, prevention is key. …”
Publicado 2023
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26424por Alkhamis, Fahad A., Alabdali, Majed M., Alsulaiman, Abdulla A., Alamri, Abdullah S., Alali, Rudaynah, Akhtar, Mohammed S., Alsalman, Sadiq A., Cyrus, Cyril, Albakr, Aishah I., Alduhalan, Anas S., Gandla, Divya, Al-Romaih, Khaldoun, Abouelhoda, Mohamed, Loza, Bao-Li, Keating, Brendan, Al-Ali, Amein K.“…We performed whole exome sequencing on 387 ischemic stroke subjects from Saudi Arabian hospital networks with up to 20,230 controls from the Saudi Human Genome Project and performed gene burden analyses of variants in 177 a priori loci derived from knowledge-driven curation of monogenic and genome-wide association studies of stroke. …”
Publicado 2023
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26425por Yu, Zhen, Chan, Shixin, Wang, Xu, Sun, Rui, Wang, Ming, Wang, Zhenglin, Zuo, Xiaomin, Chen, Jiajie, Zhang, Huabing, Chen, Wei“…CONCLUSION: Combined therapy with 5-FU and RUT exerted a superior curative effect in CRC than treatment with either single drug alone and has potential as a novel therapeutic modality for the treatment of CRC.…”
Publicado 2023
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26426por Meng, Lingfeng, Hou, Huimin, Zhang, Peng, Gu, Yinjun, Shi, Benkang, Li, Yan, Wang, Qingwei, Zhang, Yifei, Ren, Lijuan, Chen, Qi, Yuan, Zhen, Guo, Fan, Li, Dianyou, Ma, Yunfu, Dong, Sheng, Liu, Zhijun, Shang, Aijia, Li, Bo, Xu, Wei, Lv, Jianwei, Zhang, Yaoguang“…However, regular postoperative programming is crucial for the maintenance of the curative effects of electronic sacral stimulator devices. …”
Publicado 2023
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26427por Allweiss, Lena, Testoni, Barbara, Yu, Mei, Lucifora, Julie, Ko, Chunkyu, Qu, Bingqian, Lütgehetmann, Marc, Guo, Haitao, Urban, Stephan, Fletcher, Simon P, Protzer, Ulrike, Levrero, Massimo, Zoulim, Fabien, Dandri, Maura“…OBJECTIVES: A major goal of curative hepatitis B virus (HBV) treatments is the reduction or inactivation of intrahepatic viral covalently closed circular DNA (cccDNA). …”
Publicado 2023
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26428por Maimaiti, Palida, Aisilahong, Guhaer, Shu, Jiao Jiao, Rozi, Parhat, Keqike, Nuerbiya, Miao, Tianyu, Wang, Ningning“…CONCLUSION: Our results indicate that multidisciplinary rehabilitation treatments had a curative effect on both contracture of joints and the abnormal femoral circulations.…”
Publicado 2023
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26429por Guo, Fei, Yan, Yuting, Sun, Li, Han, Ruili, Zheng, Lanlan, Qin, Yuan, Wang, Shuang, Sun, Xude, Ji, Zhaohua, Gao, Changjun“…CONCLUSION: TEAS has an obvious curative effect in preventing POD and pain in the earlier stage of surgical patients. …”
Publicado 2023
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26430por Saini, Shashi, Anand, Anshul, Singh, Abhishek, Mahapatra, Baishakhi, Sirohi, Shruti, Singh, Samer, Singh, Rakesh K.“…In ancient Indian literature, metallic “bhasma,” particularly that of “swarna” or gold (fine gold particles), is indicated as one of the most prominent metal-based therapeutic medicine, which is known to impart protective and curative properties in various health issues. In this work, we elucidated the potential of swarna bhasma (SB) on the effector properties of phagocytes and antigen-activated CD4(+) T cells in augmenting the immunogenicity of L. donovani antigens. …”
Publicado 2023
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26431por Holmberg, Dag, Gottlieb-Vedi, Eivind, Hedberg, Jakob, Lindblad, Mats, Mattsson, Fredrik, Lagergren, Jesper“…This study aimed to assess whether these medications improve the survival after curatively intended treatment (including esophagectomy) for esophageal cancer in an unselected setting. …”
Publicado 2023
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26432por Bedewi, Jemal, Girum, Tadele, Tsegay, Tesfalidet, Derese, Mohamed, Yasin, Fedila, Kasahun, Abebaw Wasie“…Residence, marital status, knowledge of vaccine presence, knowledge of curative drug presence, knowledge of the incubation period, the self-rated level of knowledge and perceived risk to be infected with COVID-19 are significantly associated factors with adherence to preventive behaviours.…”
Publicado 2023
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26433por Yang, Wensu, Xia, Zhaoxin, Zhu, Yi, Tang, Hao, Xu, Huaming, Hu, Xinyi, Lin, Chunhui, Jiang, Tong, He, Pei, Shen, Jilu“…RESULTS: Our results demonstrated that FMT had a curative effect on T2D by ameliorating hyperlipidemia and hyperglycemia. …”
Publicado 2023
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26434por Takagi, Chisato, Sato, Michio, Tomita, Masato, Sugita, Atsushi, Tokuda, Toshiki, Fujiwara, Koki, Ando, Nobutoshi“…BACKGROUND: Surgical resection plays a critical role in the curative therapy of patients with gallbladder cancer. …”
Publicado 2023
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26435“…These locations were further geographically delineated into 15 cluster datasets curated from the Humanitarian Data Exchange (HDX) which were monitored by one or two taskforce members based on the size of the assigned cluster. …”
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26436por Honda, Daisuke, Ohsawa, Isao, Aizawa, Masashi, Tomino, Yasuhiko, Asanuma, Katsuhiko“…Recently, several therapeutic options have been developed for acute attacks and prophylaxis in the treatment of HAE; however, currently, there is no curative therapy for HAE. CASE PRESENTATION: Here we report the case of a 48-year-old male patient who presented with a long-standing history of HAE and underwent bone marrow transplantation (BMT) for acute myeloid leukemia (AML) at the age of 39 years and has been in complete remission of AML and HAE thereafter. …”
Publicado 2023
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26437por Wagdy, Reham, Abdel-Kader, Reham M., El-Khatib, Ahmed H., Linscheid, Michael W., Handoussa, Heba, Hamdi, Nabila“…BACKGROUND: Neuroinflammation and oxidative stress are critical players in the pathogenesis of numerous neurodegenerative diseases, such as Alzheimer’s disease (AD) which is responsible for most cases of dementia in the elderly. With the lack of curative treatments, natural phenolics are potential candidates to delay the onset and progression of such age-related disorders due to their potent antioxidant and anti-inflammatory effects. …”
Publicado 2023
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26438por Boldrini, Luca, Romano, Angela, Chiloiro, Giuditta, Corradini, Stefanie, De Luca, Viola, Verusio, Valeria, D’Aviero, Andrea, Castelluccia, Alessandra, Alitto, Anna Rita, Catucci, Francesco, Grimaldi, Gianmarco, Trapp, Christian, Hörner-Rieber, Juliane, Marchesano, Domenico, Frascino, Vincenzo, Mattiucci, Gian Carlo, Valentini, Vincenzo, Gentile, Piercarlo, Gambacorta, Maria Antonietta“…In this context, stereotactic body radiation therapy (SBRT) allows the delivery of high doses, with curative intent. Magnetic Resonance guided Radiation Therapy (MRgRT) has shown promising results in terms of safety, feasibility and efficacy of delivering SBRT thanks to the enhanced soft tissue contrast and the online adaptive workflow. …”
Publicado 2023
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26439por Liu, Kehui, Ding, Yezhou, Wang, Yun, Zhao, Qingqing, Yan, Lei, Xie, Jingdong, Liu, Yunye, Xie, Qing, Cai, Wei, Bao, Shisan, Wang, Hui“…Liver tissue was obtained from liver biopsy in CHB, HBV related cirrhosis patients or curative resection in HBV-HCC patients. Serum IL-34 and MCSF, or intrahepatic IL-34, MCSF and CD68(+) tumor associate macrophages (TAMs) were determined using ELISA or immunohistochemistry. …”
Publicado 2022
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26440por Huang, Rui, Li, Zhihui, Yang, Fan, Zhang, Yu, Jiang, Yanhui, Li, Churong, Gao, Hui, Li, Guanghui, Liu, Yimin, Guo, Wenyan, Yang, Dingqiang, Zhang, Shichuan, Li, Jie, Wen, Hao, Lang, Jinyi, Zhang, Peng“…Here, we evaluated the outcomes of patients treated with intensity‐modulated‐based pulsed low‐dose‐rate radiotherapy (PLDR‐IMRT) to enhance the curative effect of salvage treatment and reduce RT‐related SAEs. …”
Publicado 2023
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