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26641por Yeh, Chien-Hung, Bellon, Marcia, Wang, Fang, Zhang, Hong, Fu, Liwu, Nicot, Christophe“…Present treatment options are limited and there is no curative therapy for ATL. Ubiquitin ligase FBXW7 is commonly mutated or functionally inactivated in human cancers. …”
Publicado 2020
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26642por Heo, Jung Won, Kang, Hye Seon, Park, Chan Kwon, Kim, Sung Kyoung, Kim, Ju Sang, Kim, Jin Woo, Kim, Seung Joon, Lee, Sang Haak, Yeo, Chang Dong“…METHODS: We enrolled 457 patients who underwent curative surgery for NSCLC at seven hospitals at The Catholic University of Korea from 2014 to 2018. …”
Publicado 2020
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26643por Patel, Sagar A., Switchenko, Jeffrey M., Fischer-Valuck, Ben, Zhang, Chao, Rose, Brent S., Chen, Ronald C., Jani, Ashesh B., Royce, Trevor J.“…METHODS: Men > 40 years old with localized PC treated with external beam radiation and concomitant ADT for curative intent between 2004 and 2016 were analyzed from the National Cancer Database. …”
Publicado 2020
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26644“…CONCLUSION: Hybrid ESD by duodenoscope is technically challenging, and may be curative for recurrent, laterally spreading papillary adenomas < 2 cm. …”
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26645por Söderström, Henna K, Räsänen, Jari, Saarnio, Juha, Toikkanen, Vesa, Tyrväinen, Tuula, Rantanen, Tuomo, Valtola, Antti, Ohtonen, Pasi, Pääaho, Minna, Kokkola, Arto, Kallio, Raija, Karttunen, Tuomo J, Pohjanen, Vesa-Matti, Ristimäki, Ari, Laine, Simo, Sihvo, Eero, Kauppila, Joonas H“…All patients over 18 years of age, who had either curative surgery, palliative surgery or salvage surgery for primary cancer in the oesophagus are included in this study. …”
Publicado 2020
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26646“…These QTL may be useful in the curated selection of new soybean cultivars for optimized soy-based food products.…”
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26647por Crolley, Valerie E., Hanna, Daire, Joharatnam-Hogan, Nalinie, Chopra, Neha, Bamac, Ekin, Desai, Meera, Lam, Yuk-Chun, Dipro, Sabiq, Kanani, Ruhi, Benson, Jack, Wilson, William, Fox, Thomas A., Shiu, Kai-Keen, Forster, Martin, Bridgewater, John, Hochhauser, Daniel, Khan, Khurum“…OR 0.53; 95% CI 0.30–0.95). Treatment intent (curative versus palliative), hormonal- or immunotherapy and solid versus haematological cancers had no significant effect on risk. …”
Publicado 2020
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26648por Xiao, Binyi, Peng, Jianhong, Wang, Yongchun, Deng, Yuxiang, Ou, Qingjian, Wu, Xiaojun, Lin, Junzhong, Pan, Zhizhong, Zhang, Lin“…BACKGROUND: The aim of this study was to assess the prognostic value of CD8+ tumor infiltrating lymphocytes (TIL) combined with programmed cell death-ligand 1 (PD-L1) expression for patients with solitary colorectal cancer liver metastasis (SCLM) undergoing R0 resection METHODS: Patients undergoing curative hepatectomy for SCLM were reviewed. Immunohistochemical multiplex technique was used for quantifying CD8+ TIL, and immunohistochemical staining was used for assessing PD-L1 expression. …”
Publicado 2020
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26649por He, Yuqing, Deng, Jiaxin, Zhao, Yi, Tao, Huiqian, Dan, Hongxia, Xu, Hao, Chen, Qianming“…METHODS: A systematic review and meta-analysis were conducted to assess the curative effect of PDT. Five electronic databases were searched, PubMed, Web of Science, the Cochrane Library, Embase, and EBSCO up to 1 December, 2019. …”
Publicado 2020
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26650“…Mechanically, miR-16-5p could regulate TLN1 expression via target binding, and depleting TLN1 could counteract the inhibitory effect of miR-16-5p knockdown on the curative effect of TIIA in T98G and A172 cells. CONCLUSION: TIIA exerted the anti-proliferation, anti-migration and anti-invasion role in glioma cells both in vitro and in vivo partially through regulating miR-16-5p/TLN1 axis.…”
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26651por Noriega, Daniel D., Arraes, Fabricio B. M., Antonino, José Dijair, Macedo, Leonardo L. P., Fonseca, Fernando C. A., Togawa, Roberto C., Grynberg, Priscila, Silva, Maria C. M., Negrisoli, Aldomario S., Grossi-de-Sa, Maria F.“…In this study, the objective was to evaluate the transcriptome responses of the SGB’s gut in order to provide curated data of genes that could be used for pest management by RNAi in future studies. …”
Publicado 2020
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26652“…METHODS: Consecutive patients with pathologically confirmed lung ASC receiving curative resection from January 2007 to December 2017 at our center were retrospectively reviewed. …”
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26653“…In particular, we manually curated a benchmark dataset containing 185 GO annotations for 62 circRNAs, namely, circRNA2GO-62. …”
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26654“…BACKGROUND: Although Borrmann type IV (B-4) gastric cancer has a higher mortality rate and presents distant metastasis easily, especially peritoneal metastasis, when diagnosed, some B-4 patients were found to have no distant metastasis by preoperative detection and underwent curative surgery, which was defined as circumscribed B-4 in our study. …”
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26655por Colina, Andreina, Hwang, Hyunsoo, Wang, Huamin, Katz, Matthew H G, Sun, Ryan, Lee, Jeffrey E, Thomas, Jane, Tzeng, Ching-Wei, Wolff, Robert A, Raghav, Kanwal, Overman, Michael J“…OBJECTIVE: Small bowel adenocarcinoma (SBA) is a rare malignancy with limited evidence regarding outcomes after curative resection of localised disease. We aimed to evaluate presentation and prognostic factors affecting overall survival (OS), relapse-free survival (RFS) and recurrence of SBA. …”
Publicado 2020
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26656por Yin, Andrew Lukas, Gheissari, Pargol, Lin, Inna Wanyin, Sobolev, Michael, Pollak, John P, Cole, Curtis, Estrin, Deborah“…Building a platform that focuses on providing and curating the information used for self-assessment could help physicians make more accurately informed changes to their own clinical practice and decision-making.…”
Publicado 2020
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26657por Prawer, Yair D. J., Stroehlein, Andreas J., Young, Neil D., Kapoor, Shilpa, Hall, Ross S., Ghazali, Razi, Batterham, Phillip, Gasser, Robin B., Perry, Trent, Anstead, Clare A.“…METHODS: Here, we employed a bioinformatics workflow to curate the SCP/TAPS protein gene family in L. cuprina. …”
Publicado 2020
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26658por Takekuma, Munetaka, Takahashi, Fumiaki, Mabuchi, Seiji, Kudaka, Wataru, Horie, Koji, Ikeda, Mariko, Shikama, Ayumi, Mitsuhashi, Akira, Nagao, Shoji, Suzuki, Shiro, Mizuno, Mika, Nishio, Shin, Tokunaga, Hideki, Ota, Yukinobu, Kasamatsu, Takahiro, Kitagawa, Ryo, Toita, Takafumi, Kobayashi, Hiroaki, Ishikawa, Mitsuya, Yaegashi, Nobuo“…This indicates that salvage HT could be curative treatment for those patients. Further prospective clinical trials with regard to salvage HT after RT/CCRT are warranted. …”
Publicado 2020
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26659por Harris, Micah K, Yadav, Viveka Nand, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Mullan, Brendan, Miklja, Zachary, Siada, Ruby, Ravindran, Ramya, Cao, Xuhong, Pasternak, Amy, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, Desprez, Pierre, McAllister, Sean, Venneti, Sriram, Koschmann, Carl“…BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors with no curative therapies. Inhibitor of DNA binding (ID) proteins are key regulators of gene differentiation during embryogenesis. …”
Publicado 2020
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26660por Khan, Sara, Solano-Paez, Palma, Suwal, Tannu, Al-Karmi, Salma, Lu, Mei, Ho, Ben, Fouladi, Maryam, Leary, Sarah, Levy, Jean M Mulcahy, Lassaletta, Alvaro, Rivas, Eloy, Reddy, Alyssa, Gillespie, G Yancey, Gupta, Nalin, Yalon-Oren, Michal, Amariglio, Laura, Nakamura, Hideo, Wu, Kuo-Sheng, Wong, Tai-Tong, Ra, Young-Shin, Spina, Milena La, Emanuele, Policlinico Vittorio, Massimi, Luca, Buccoliero, Anna Maria, Hansford, Jordan R, Grundy, Richard G, Adamek, Dariusz, Fangusaro, Jason, Scharnhorst, David, Johnston, Donna, Lafay-Cousin, Lucie, Camelo-Piragua, Sandra, Kabbara, Nabil, Gajjar, Amar, Boutarbouch, Mahjouba, da Costa, Maria Joao Gil, Hanson, Derek, Wood, Paul, Al-Hussaini, Maysa, Amayiri, Nisreen, Wang, Yin, Catchpoole, Daniel, Michaud, Jean, Bendel, Anne E, Ellezam, Benjamin, Gerber, Nicholas, Plant, Ashley, Jeffery, Rubens, Dunham, Christopher, Moertel, Christopher, Walter, Andrew, Ziegler, David, Dodgshun, Andrew, Gottardo, Nicholas, Demir, Ahmet, Ramanujachar, Ramya, Raabe, Eric, Mary, Shago, Dirks, Peter, Taylor, Michael, Eugene, Hwang, Lindsey, Holly, Tihan, Tarik, Mette, Jorgensen, Dahl, Christine, Low, Sharon, Smith, Amy, Hazrati, Lili-Naz, Kresak, Jesse, Gino, Somers, Tan, Enrica, Morales, Andres, Santa-Maria, Vicente, Hawkins, Cynthia, Bartels, Ute, Stephens, Derek, Nobusawa, Sumihito, Dufour, Christelle, Bourdeaut, Franck, Andre, Nicolas, Bouffet, Eric, Huang, Annie“…Uni-and multivariate analyses of clinical and treatment details of curative regimens available for 110 patients identified metastatic disease (p=0.002), brainstem locations(p=0.005), extent of surgery, receipt of multi-modal therapy including high dose chemotherapy and radiation (P<0.001) as significant treatment prognosticators, while C19MC status, age and gender were non-significant risk factors. …”
Publicado 2020
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