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  1. 26981
    “…In general, repeated doses are more curative than single. There is a zone between the therapeutic and toxic doses, both single and repeated, for all these chemicals alike, where the natural resistance of the animal to an infection is reduced. …”
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    STUDY OF THE ACTION OF FOUR AROMATIC CINCHONA DERIVATIVES ON PNEUMOCOCCUS. A COMPARISON WITH OPTOCHIN
  2. 26982
    “…The accuracy of the proposed method was close to the accuracy of manually-curated peak matching, which required tens of man-hours for the analyzed data sets. …”
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    A dynamic programming approach for the alignment of signal peaks in multiple gas chromatography-mass spectrometry experiments
  3. 26983
    “…BACKGROUND: Experimentally verified protein-protein interactions (PPI) cannot be easily retrieved by researchers unless they are stored in PPI databases. The curation of such databases can be made faster by ranking newly-published articles' relevance to PPI, a task which we approach here by designing a machine-learning-based PPI classifier. …”
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    Exploiting likely-positive and unlabeled data to improve the identification of protein-protein interaction articles
  4. 26984
    “…BACKGROUND: Providing reproductive and sexual health services is an important and challenging aspect of caring for displaced populations, and preventive and curative sexual health services may play a role in reducing HIV transmission in complex emergencies. …”
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    Reproductive health for refugees by refugees in Guinea II: sexually transmitted infections
  5. 26985
    “…Using the new EST evidence, automated and manual curation has resulted in substantial improvements to the over 24,000 gene models, which will be valuable to researchers studying this model organism as well as for comparative genomics purposes.…”
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    Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure
  6. 26986
    “…RESULTS: The cohort comprised 2,831 patients. Curative regimens containing an artemisinin derivative were given to 90.8% (n = 2,574) of patients, although 33% (n = 936) of patients received an artemisinin-based monotherapy. …”
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    Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy
  7. 26987
    “…OBJECTIVE: Curative surgery is not an option for many patients with clinical stage I non-small-cell lung carcinoma (NSCLC), but radical radiosurgery may be effective. …”
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    Radical cyberknife radiosurgery with tumor tracking: an effective treatment for inoperable small peripheral stage I non-small cell lung cancer
  8. 26988
    “…However, a comprehensive manual curation remains to be performed. Gene Ontology (GO) annotation is a valuable means of assigning functional information using standardized vocabulary. …”
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    Gene Ontology annotation of the rice blast fungus, Magnaporthe oryzae
  9. 26989
    “…Assembly and manual curation yielded sequence scaffolds of 172 kbp (3CAR) and 94 kbp (CYP720B4) long. …”
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    Targeted isolation, sequence assembly and characterization of two white spruce (Picea glauca) BAC clones for terpenoid synthase and cytochrome P450 genes involved in conifer defence reveal insights into a conifer genome
  10. 26990
    por Witter, Sophie, Garshong, Bertha
    Publicado 2009
    “…The NHIS has had a considerable impact on the health system as a whole, taking on a growing role in funding curative care. In 2009, it is expected to contribute 41% of the overall resource envelope. …”
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    Something old or something new? Social health insurance in Ghana
  11. 26991
    “…As the primary clinical endpoint, overall-survival in patients receiving postoperative radiation therapy vs. patients without adjuvant therapy following curative intended surgery is compared. The aim of the study is to enroll 560 adult males and females for 1:1 randomization to one of the two treatment arms (irradiation/no irradiation). …”
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    Effectiveness of adjuvant radiotherapy in patients with oropharyngeal and floor of mouth squamous cell carcinoma and concomitant histological verification of singular ipsilateral cervical lymph node metastasis (pN1-state) - A prospective multicenter randomized controlled clinical trial using a comprehensive cohort design
  12. 26992
    “…Accurate gene annotation is facilitated by the annotation of pseudogenes and regulatory elements. Manually curated gene models will be incorporated into the Ensembl and Consensus Coding Sequence (CCDS) reference sets. …”
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    Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome
  13. 26993
    “…UniProt database includes a controlled and curated vocabulary of specific descriptors or keywords. …”
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    Projection of gene-protein networks to the functional space of the proteome and its application to analysis of organism complexity
  14. 26994
    “…We conclude that given the present density of health facilities in Kenya, geographic access to curative services does not influence population-level mortality.…”
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    Geographic access to care is not a determinant of child mortality in a rural Kenyan setting with high health facility density
  15. 26995
    por Boominathan, Lakshmanane
    Publicado 2010
    “…Here, I present evidence for the first time that the tumor suppressors p53, p63, and p73 function as both positive and negative regulators of the miRNA processing components. Curated p53-dependent miRNA expression data was used to identify p53-miRs that target the components of the miRNA-processing complex. …”
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    The Tumor Suppressors p53, p63, and p73 Are Regulators of MicroRNA Processing Complex
  16. 26996
    “…CONCLUSION: Smad6 together with Smad2 may be prognostic factors, independent of nodal status in oral SCC after curative resection. The underlying mechanism which involves aberrant TGFβ signaling should be better clarified in the future.…”
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    Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients
  17. 26997
    “…METHODS/DESIGN: Using a single-center, randomized design, 160 subjects (40 patients/study arm) with histologically confirmed stage I-IIIA NSCLC following curative-intent complete surgical resection at Duke University Medical Center (DUMC) will be potentially eligible for this trial. …”
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    The lung cancer exercise training study: a randomized trial of aerobic training, resistance training, or both in postsurgical lung cancer patients: rationale and design
  18. 26998
    “…Despite its status as a developing nation, South Africa has a relatively strong history of marine taxonomic research and maintains comprehensive and well-curated museum collections totaling over 291,000 records. …”
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    Marine Biodiversity in South Africa: An Evaluation of Current States of Knowledge
  19. 26999
    “…We introduce the Nutrigenomics Organisation (NuGO, http://www.nugo.org) as a membership association responsible for establishing and curating the dbNP. Within NuGO, all efforts related to dbNP (i.e. usage, coordination, integration, facilitation and maintenance) will be directed towards a sustainable and federated infrastructure.…”
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    Challenges of molecular nutrition research 6: the nutritional phenotype database to store, share and evaluate nutritional systems biology studies
  20. 27000
    “…Even in those patients with low-grade gliomas, that imply a moderately good prognosis, treatment is almost never curative. Recent studies have demonstrated the existence of a small fraction of glioma cells with characteristics of neural stem cells which are able to grow in vitro forming neurospheres and that can be isolated in vivo using surface markers such as CD133. …”
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    Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas
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