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27041por Twigt, Bas A, Scholten, Anouk, Valk, Gerlof D, Rinkes, Inne HM Borel, Vriens, Menno R“…In all, parathyroidectomy is the only curative treatment. Nevertheless, there are important differences in clinical expression and treatment. …”
Publicado 2013
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27042“…BACKGROUND: Diagnosis of early-stage hepatocellular carcinoma (HCC) followed by curative resection or liver transplantation offers the best chance for long-term patient survival. …”
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27043por Ho, Judy WC, Lee, Antoinette M, Macfarlane, Duncan J, Fong, Daniel YT, Leung, Sharron, Cerin, Ester, Chan, Wynnie YY, Leung, Ivy PF, Lam, Sharon HS, Taylor, Aliki J, Cheng, Kar-keung“…Two hundred and twenty-two colorectal cancer patients who completed curative treatment without evidence of recurrence will be recruited into the study. …”
Publicado 2013
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27044por Jacobs, Laura Ann, Bewicke-Copley, Findlay, Poolman, Mark Graham, Pink, Ryan Charles, Mulcahy, Laura Ann, Baker, Isabel, Beaman, Ellie-May, Brooks, Travis, Caley, Daniel Paul, Cowling, William, Currie, James Michael Stevenson, Horsburgh, Jessica, Kenehan, Lottie, Keyes, Emma, Leite, Daniel, Massa, Davide, McDermott-Rouse, Adam, Samuel, Priya, Wood, Hannah, Kadhim, Munira, Carter, David Raul Francisco“…To facilitate this we created and manually curated the miRStress database, which describes the changes in miRNA levels following an array of stress types in eukaryotic cells. …”
Publicado 2013
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27045por LI, YAN, MIAO, LIYUN, CAI, HOURONG, DING, JINGJING, XIAO, YONGLONG, YANG, JUN, ZHANG, DEPING“…Furthermore, a panel of formalin-fixed paraffin-embedded NSCLC tissues from 127 patients undergoing curative resection (stages I, II and III) between January, 2003 and December, 2008 were obtained in order to investigate the correlation between GPC5 expression and clinicopathological factors using immunohistochemical methods. …”
Publicado 2013
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27046por Novichkov, Pavel S, Kazakov, Alexey E, Ravcheev, Dmitry A, Leyn, Semen A, Kovaleva, Galina Y, Sutormin, Roman A, Kazanov, Marat D, Riehl, William, Arkin, Adam P, Dubchak, Inna, Rodionov, Dmitry A“…We significantly expanded a reference collection of manually curated regulons we introduced earlier. RegPrecise 3.0 provides access to inferred regulatory interactions organized by phylogenetic, structural and functional properties. …”
Publicado 2013
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27047“…Cataract surgery is a curative and cost-effective intervention. Despite major non-governmental organization (NGO) support, the cataract surgery performed in Southern Region, Ethiopia is currently insufficient to address the need. …”
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27048por Arif, Adnan, Abideen, Zain Ul, Zia, Naeem, Khan, Muhammad Atif, Nawaz, Tariq, Malik, Asif Zafar“…Typically, splenic metastasis from endometrial carcinomas present months to years after curative surgery, chemotherapy or radiotherapy. The most common complaint in symptomatic patients is abdominal pain localized to the left hypochondrium. …”
Publicado 2013
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27049“…CONCLUSIONS: Although its coverage and precision are acceptable, GS, because of its incomplete recall, should not be used as a single source in SR searching. A specialized, curated medical database such as PubMed provides experienced searchers with tools and functionality that help improve recall, and numerous options in order to optimize precision. …”
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27050“…The process flow described provides specific information on the scope and degree of conservation for the analyzed protein sequences and annotations and will be used to enrich the quality of RefSeq records by identifying targets for further improvement in the computational annotation pipeline, and by flagging specific genes for manual curation.…”
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27051“…Species with recorded highest consensus for curative role are a useful pool for further phytochemical and pharmacological validation for better utilization. …”
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27052por Nagy, Alinda, Szláma, György, Szarka, Eszter, Trexler, Mária, Bányai, László, Patthy, László“…To estimate the contribution of errors in gene prediction to differences in DA of predicted proteins, we have used the high quality manually curated UniProtKB/Swiss-Prot database as a reference. …”
Publicado 2011
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27053por Lee, Joo Yong, Lee, Dae Hun, Cho, Nam Hoon, Rha, Koon Ho, Choi, Young Deuk, Hong, Sung Joon, Yang, Seung Choul, Cho, Kang Su“…The comorbidities of a patient should be considered before selecting RP as a curative modality for PCa.…”
Publicado 2014
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27054por Siewe, Basile, Wallace, Jennillee, Rygielski, Sonya, Stapleton, Jack T., Martin, Jeffrey, Deeks, Steven G., Landay, Alan“…Despite antiretroviral therapy (ART), attenuated anti-HIV CTL functions present a major hurdle towards curative measures requiring viral eradication. Therefore, deeper understanding of the mechanisms underlying impaired CTL is crucial before HIV viral eradication is viable. …”
Publicado 2014
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27055por Li, Qigui, O’Neil, Michael, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Pybus, Brandon, Hickman, Mark, Melendez, Victor“…TQ is highly effective for causal prophylaxis in mice at a minimal curative single oral dose of 5 mg/kg, which is a five-fold improvement in potency versus PQ. …”
Publicado 2014
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27056“…These should be useful for studies of specific genes and gene families of interest as well as for curating draft genome assemblies as they become available.…”
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27057The Risa R/Bioconductor package: integrative data analysis from experimental metadata and back againpor González-Beltrán, Alejandra, Neumann, Steffen, Maguire, Eamonn, Sansone, Susanna-Assunta, Rocca-Serra, Philippe“…RESULTS: The Risa package bridges the gap between the metadata collection and curation in an ISA-compliant way and the data analysis using the widely used statistical computing environment R. …”
Publicado 2014
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27058por Campbell, Lee, Al-Jayyoussi, Ghaith, Gutteridge, Robert, Gumbleton, Nigel, Griffiths, Rosie, Gumbleton, Simon, Smith, Mathew W, Griffiths, David FR, Gumbleton, Mark“…BACKGROUND: Up to 40% of patients initially diagnosed with clinically-confined renal cell carcinoma (RCC) and who undergo curative surgery will nevertheless relapse with metastatic disease (mRCC) associated with poor long term survival. …”
Publicado 2013
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27059por Fristedt, Richard, Gaber, Alexander, Hedner, Charlotta, Nodin, Björn, Uhlén, Mathias, Eberhard, Jakob, Jirström, Karin“…High PIGR expression was an independent predictor of a prolonged OS (HR = 0.60, 95% CI 0.36-0.99) and RFS (HR = 0.49, 95% CI 0.27-0.90) in patients with radically resected (R0) primary tumours and of an improved RFS (HR = 0.32, 95% CI 0.15-0.69) in curatively treated patients with R0 resection/distant metastasis-free disease. …”
Publicado 2014
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27060“…However, this approach might fail if the employed libraries are not up to date with the latest research, don't capture relevant biological themes or are curated at a different level of granularity than is required to appropriately analyze the input gene set. …”
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