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  1. 27081
    “…Importantly, using TCR Vβ spectratyping, we also demonstrated the presence of GvM unique responses potentially associated with the curative capacity of this immunotherapeutic approach.…”
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    Establishment of a Murine Graft-versus-Myeloma Model Using Allogeneic Stem Cell Transplantation
  2. 27082
    “…Two new benchmark datasets are provided, which are over an order of magnitude larger than existing manually curated ones. These tools enable the comprehensive study of several aspects of protein–protein contacts in the PDB and represent a basis for future, even larger scale studies of protein–protein interactions.…”
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    A PDB-wide, evolution-based assessment of protein–protein interfaces
  3. 27083
    “…METHODS: Pathologic data were retrospectively evaluated for 206 patients who underwent curative resection of PA. We investigated how histologic component occupancy rates changed as tumor size and N stage increased. …”
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    Correlation of histological components with tumor invasion in pulmonary adenocarcinoma
  4. 27084
    “…RESULTS: We present a curated list of 220 GPCRs in the sponge genome after excluding incomplete sequences and false positives from our initial dataset of 282 predicted GPCR sequences obtained using Pfam search. …”
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    The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
  5. 27085
    “…Early and normative surgery is the only curative method for MEN 2-related medullary thyroid carcinoma (MTC). …”
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    Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese
  6. 27086
    “…BACKGROUND: Lung cancer stage at diagnosis predicts possible curative treatment. In Denmark and the UK, lung cancer patients have lower survival rates than citizens in most other European countries, which may partly be explained by a comparatively longer diagnostic interval in these two countries. …”
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    The role of general practice in routes to diagnosis of lung cancer in Denmark: a population-based study of general practice involvement, diagnostic activity and diagnostic intervals
  7. 27087
    “…The consistent results were steadily observed across cultivated (Oryza sativa and O. glaberrima) and wild (O. rufipogon and O. nivara) rice species, asserting the necessity of our curation of the crop genome annotations. Our comparative analyses also inferred the common ancestral transcriptome of grass plants and gain- and loss-of-ASV events. …”
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    Comparative genomics of grass EST libraries reveals previously uncharacterized splicing events in crop plants
  8. 27088
    “…La radio-chimiothérapie concomitante postopératoire pourrait être un régime efficace et sûre chez les patients ayant bénéficié d'une gastrectomie à visée curative dans le cancer de l'estomac localement avancé.…”
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    Radio-chimiothérapie adjuvante des adénocarcinomes gastriques: à propos de 34 cas et d'une revue de la literature
  9. 27089
    “…METHODS: This retrospective study included all breast cancer patients received curative BCS without PORT between 2003 and 2013. In the PORT omission group, characteristics and local recurrence differences were compared between the recommended group and the refused group. …”
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    Proportion and Clinical Outcomes of Postoperative Radiotherapy Omission after Breast-Conserving Surgery in Women with Breast Cancer
  10. 27090
    “…However, researches have indicated that the curative effect lies in a combination of auditory and vagal nerve stimulation. …”
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    Transcutaneous electrical stimulation at auricular acupoints innervated by auricular branch of vagus nerve pairing tone for tinnitus: study protocol for a randomized controlled clinical trial
  11. 27091
    por Köhl, Karin, Gremmels, Jürgen
    Publicado 2015
    “…Datasets are linked to the original and curated data files stored on a file server. The ownership stamp, project affiliation and date stamp of a dataset are used to regulate data access, which is restricted to data belonging to the user or to his projects and data, for which the embargo period has ended. …”
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    A software tool for the input and management of phenotypic data using personal digital assistants and other mobile devices
  12. 27092
    “…Tumor recurrence, advanced local growth and metastasis are key factors that frequently prevent these tumors from curative surgical treatment. Preclinical research has demonstrated that the dependency of these tumors on supporting mesenchymal stroma results in susceptibility to cell-based therapies targeting this stroma. …”
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    Treatment of advanced gastrointestinal tumors with genetically modified autologous mesenchymal stromal cells (TREAT-ME1): study protocol of a phase I/II clinical trial
  13. 27093
    “…BACKGROUND: Alzheimer’s disease (AD) is the most common cause of dementia with no curative therapy currently available. Establishment of sensitive and non-invasive biomarkers that promote an early diagnosis of AD is crucial for the effective administration of disease-modifying drugs. …”
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    MicroRNA-Seq Data Analysis Pipeline to Identify Blood Biomarkers for Alzheimer’s Disease from Public Data
  14. 27094
    “…Allogeneic stem cell transplantation (allo-HSCT) is one of the curative treatments for hematologic malignancies, but is hampered by severe complications, such as acute or chronic graft-versus-host-disease (aGvHD; cGvHD) and infections. …”
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    Long term follow up of patients after allogeneic stem cell transplantation and transfusion of HSV-TK transduced T-cells
  15. 27095
    “…METHODS: We investigated associations among P53 mutant (P53(Mut)) expression, and P16 and Smad4 loss-of-expression, with clinical outcome in 120 LAC patients who underwent curative resection, using immunohistochemical (IHC) methods. …”
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    Clinical outcome and expression of mutant P53, P16, and Smad4 in lung adenocarcinoma: a prospective study
  16. 27096
    “…From eight HCC patients undergoing curative surgery, array-based DNA methylation and gene expression data of all annotated genes were analyzed by comparing HCC tissue and homologous cancer-free liver tissue. …”
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    DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma
  17. 27097
    “…Patients received salvage SBRT with curative intent. Dose and fractionation were based on tumor location and size, with a median prescription dose of 48 Gy in 4 fractions (range 20–60 Gy in 1–4 fractions). …”
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    Salvage Stereotactic Body Radiotherapy for Locally Recurrent Non-Small Cell Lung Cancer after Sublobar Resection and I(125) Vicryl Mesh Brachytherapy
  18. 27098
    por Ernst, Patrick, Siu, Amy, Weikum, Gerhard
    Publicado 2015
    “…First, most biomedical KBs are manually built and curated, and cannot keep up with the rate at which new findings are published. …”
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    KnowLife: a versatile approach for constructing a large knowledge graph for biomedical sciences
  19. 27099
    “…Since its introduction in 1947, MTX-containing chemotherapeutic regimens have proven instrumental in achieving curative effects in acute lymphoblastic leukemia (ALL). …”
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    Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia
  20. 27100
    “…Il s'agit d'une étude rétrospective et descriptive de 10 ans (2000- 2009) effectuée dans un CHU de chirurgie générale et d'Oncologie sur 62 patientes ayant développé un cancer de l'ovaire et opérées à visée curative. L’âge moyen des patientes était de 43 ans dont 53,23% avaient plus de 45 ans. …”
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    Une étude rétrospective sur le cancer de l'ovaire avec un recul médian de 42 mois
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