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  1. 27221
    “…BACKGROUND: Glioblastoma (GBM) is a highly aggressive primary brain cancer, for which curative therapies are not available. An emerging therapeutic approach suggested to have potential to target malignant gliomas has been based on the use of multipotent mesenchymal stem cells (MSCs), either unmodified or engineered to deliver anticancer therapeutic agents, as these cells present an intrinsic capacity to migrate towards malignant tumors. …”
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    Impact of mesenchymal stem cells’ secretome on glioblastoma pathophysiology
  2. 27222
    “…In over two thirds (69%) of the countries, the content of services was mixed, consisting of preventive and curative services, and in 29% preventive only. OHS financing was organized according to a mixed model among 63% and by employers only among 33% of the respondents. …”
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    A global survey on occupational health services in selected international commission on occupational health (ICOH) member countries
  3. 27223
    “…The majority were men (85%), white (55%) with genotype 1 HCV (66%), Child-Pugh score A (85%), tumor stage 4 (41%) and eligible for potentially curative options (74%). The SVR12 (ITT) data are depicted in table. …”
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    The use of Direct-Acting Antivirals in Hepatitis C Virus-Infected Patients with Hepatocellular Carcinoma
  4. 27224
    “…BACKGROUND: Those in safety-net hospitals are especially vulnerable to lack of access to specialty care and curative treatment (Tx) for hepatitis C (HCV). We examined predictors of receiving HCV Tx in safety-net hospitals. …”
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    Mental Health, Heart Disease, and Lack of Insurance Associated with Not Receiving Hepatitis C Treatment in Safety-Net Hospitals
  5. 27225
    por Beck, Tim N., Golemis, Erica A.
    Publicado 2016
    “…Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and is frequently impervious to curative treatment efforts. Similar to other cancers associated with prolonged exposure to carcinogens, HNSCCs often have a high burden of mutations, contributing to substantial inter- and intra-tumor heterogeneity. …”
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    Genomic insights into head and neck cancer
  6. 27226
    “…One projection included the interventions and targets from Mali’s ten-year health strategy (PDDSS) for 2014-2023, and two others modeled intervention packages that included scale up of antenatal, intrapartum, and curative interventions, as well as reductions in stunting and wasting. …”
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    Using the Lives Saved Tool to aid country planning in meeting mortality targets: a case study from Mali
  7. 27227
    “…The aim of the study was to review the operative experiences of emergency hysterectomy for life-threatening postpartum hemorrhage (PPH) performed over a 12-year period at Fujian Provincial Maternity and Children's Hospital; to examine the incidence and risk factors for emergency obstetric hysterectomy; and to evaluate the curative effectiveness and safety of subtotal hysterectomy for life-threatening PPH. …”
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    Emergency obstetric hysterectomy for life-threatening postpartum hemorrhage: A 12-year review
  8. 27228
    “…Transcatheter arterial chemoembolization (TACE) is the main treatment for intermediate end-stage HCC, while it is only a palliative and not a curative treatment due to the existence of residual tumors, and radiofrequency ablation (RFA) has limitations in complete ablation of large HCC. …”
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    Transcatheter Arterial Chemoembolization Combined with Simultaneous Computed Tomography-guided Radiofrequency Ablation for Large Hepatocellular Carcinomas
  9. 27229
    “…We broke down high-cost beneficiaries by demographics, the most cost-incurring condition per beneficiary and expensive treatment use. SETTING: Dutch curative health system, a health system with universal coverage. …”
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    Characteristics and healthcare utilisation patterns of high-cost beneficiaries in the Netherlands: a cross-sectional claims database study
  10. 27230
    “…Due to late stage and waiting times, only 13.5% of the patients received curative radiotherapy doses. HIV-positive CCPs presented more often with advanced disease compared to HIV negative CCPs ((44.6%) versus 39.7%, p = 0.007). …”
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    Cervical cancer patients presentation and survival in the only oncology referral hospital, Ethiopia: a retrospective cohort study
  11. 27231
    “…Although morphologically CoCC mimics intrahepatic cholangiocarcinoma (ICC), CoCC exhibits a unique intermediate biologic behavior between hepatocellular carcinoma (HCC) and ICC. Curative resection is required for prolonged survival in patients with CoCC. …”
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    Successful local treatment for repeated hepatic recurrences of cholangiolocellular carcinoma: a report on a long-term survivor
  12. 27232
    “…BACKGROUND: Fruits of Withania coagulans (Solanaceae) reported to possess several bioactive compounds as curative agents for various clinical conditions. Cisplatin is a chemotherapeutic drug to treat sarcomas, carcinomas, lymphomas, cervical cancer, germ cell tumors, etc. …”
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    Protective Effect of Withania coagulans Fruit Extract on Cisplatin-induced Nephrotoxicity in Rats
  13. 27233
    “…However, relevant randomized controlled trials showing the curative effect of these techniques remain lacking to date. …”
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    Effect of joint mobilization techniques for primary total knee arthroplasty: Study protocol for a randomized controlled trial
  14. 27234
    “…Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in humans, but still no curative treatment has been developed. Although many explicative theories have been proposed, precise pathophysiological mechanisms are unknown. …”
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    Involvement of Astrocytes in Alzheimer’s Disease from a Neuroinflammatory and Oxidative Stress Perspective
  15. 27235
    “…The association of pathway classified TNBC sub-groups to clinical outcomes was tested using Cox regression model. RESULTS: Among 4729 curated canonical pathways in GSEA database, 133 Yin pathways (FDR < 0.05) and 71 Yang pathways (p-value <0.05) were discovered in TNBC. …”
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    The exploration of contrasting pathways in Triple Negative Breast Cancer (TNBC)
  16. 27236
    “…A salvage treatment with acceptable toxicity might postpone the start of androgen deprivation treatment, might have a positive influence on the patients’ quality of life, and might even be curative. Here, toxicity and biochemical outcome are described after magnetic resonance imaging–guided focal salvage high-dose-rate brachytherapy in patients with radiorecurrent prostate cancer. …”
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    Focal MRI-Guided Salvage High-Dose-Rate Brachytherapy in Patients With Radiorecurrent Prostate Cancer
  17. 27237
    “…RESULTS: By manually curating experimental data from research articles, we obtained 332, 144, 135, and 140 verified substrate sites for K (lysine), R (arginine), T (threonine), and P (proline) residues, respectively, from 241 carbonylated proteins. …”
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    MDD-carb: a combinatorial model for the identification of protein carbonylation sites with substrate motifs
  18. 27238
    “…We retrospectively analyzed 161 patients who underwent curative resection for node-positive AGC between 2001 and 2010, evaluating the association between FR, lymph node ratio (LNR), and micrometastasis, and the relationship between FR and clinicopathologic findings, overall survival (OS) and disease-free survival (DFS). …”
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    Prognostic value of fibrosis ratio in metastatic lymph nodes of node-positive advanced gastric cancer
  19. 27239
    “…BACKGROUND: Oxidative stress as well as bacterial and fungal infections are common source of diseases while plants are source of medication for curative or protective purposes. Hence, aim of study was to compare the pharmacological potential of seven grass species in two different solvents i.e. ethanol and acetone. …”
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    Evaluation of biological potential of selected species of family Poaceae from Bahawalpur, Pakistan
  20. 27240
    “…BACKGROUND: Given the world’s aging population, it is important to identify strategies that promote healthy cognitive aging and minimize cognitive decline. Currently, no curative pharmaceutical therapy exists for cognitive impairment and dementia. …”
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    The effects of an 8-week computerized cognitive training program in older adults: a study protocol for a randomized controlled trial
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