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27421“…Griscelli syndrome is a rare disorder characterized by partial albinism, silver hair and immune failure with alteration in genes necessary for melanin transport, which is curative by stem cell transplant. Although late endocrinopathies are quite common in other disorders after stem cell transplant, these complications have not been reported in Griscelli syndrome. …”
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27422“…Clinical data in EHR and institutional registries are typically free text narratives absent common data elements (CDE). Curating existing data into CDE with machine learning (ML) may inform contemporary approaches (RWE, N-of-1 trials, and precision medicine) that are dependent on large high-quality datasets. …”
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27423por Chishti, Shahrukh, Jaggi, Karan Raj, Saini, Anuj, Agarwal, Gaurav, Ranjan, Ashish“…The current iteration relies on static, manually curated values for calculating the degree of association. …”
Publicado 2020
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27424por Chen, Guizhen, Wang, Xue, Zhang, Shuo, Xu, Xiaokang, Liang, Junquan, Xu, Yunxiang“…There are still several factors restrict our research such as no unified standard of diagnostic criteria and curative effect evaluation. TRIAL REGISTRATION: Chinese Clinical Trial Registry, ChiCTR-INR-16009724, registered in November 2016.…”
Publicado 2020
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27425“…LESSONS: S-1 plus apatinib followed by a timely esophagectomy with curative intent might be an alternative option for chemotherapy-refractory SCCE in selected patients. …”
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27426“…OBJECTIVE: To investigate the curative and adverse effects (AEs) of additional use of nimotuzumab combined with induction chemotherapy and concurrent chemoradiotherapy in unresectable locoregionally advanced hypopharyngeal carcinoma. …”
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27427por Zhang, Ting, Wang, Mengmeng, Zhang, Xiangnan, Hu, Jie, Dou, Weijia, Fan, Qingling, Feng, Dayun, Liu, Lei“…BACKGROUND: Liver resection has been widely applied as a curative measure in the treatment of hepatocellular carcinoma (HCC) patients. …”
Publicado 2020
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27428por Catanzaro, Michele, Lanni, Cristina, Basagni, Filippo, Rosini, Michela, Govoni, Stefano, Amadio, Marialaura“…Age-related macular degeneration (AMD) is a common disease with a multifactorial aetiology, still lacking effective and curative therapies. Among the early events triggering AMD is the deterioration of the retinal pigment epithelium (RPE), whose fundamental functions assure good health of the retina. …”
Publicado 2020
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27429por Zhang, Mengping, Huang, He, Li, Xueying, Huang, Ying, Chen, Chunyan, Fang, Xiaojie, Wang, Zhao, Guo, Chengcheng, Lam, Sioteng, Fu, Xiaohong, Hong, Huangming, Tian, Ying, Lu, Taixiang, Lin, Tongyu“…Conclusions: This regimen resulted in significantly improved efficacy and survival, which indicates a potentially curative role for chemotherapy-naïve mNPC, especially in newly diagnosed patients. …”
Publicado 2020
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27430Publicado 2015“…It may be considered as reference index of the treatment and observation index of curative effect.…”
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27431por Russakoff, Daniel B., Mannil, Suria S., Oakley, Jonathan D., Ran, An Ran, Cheung, Carol Y., Dasari, Srilakshmi, Riyazzuddin, Mohammed, Nagaraj, Sriharsha, Rao, Harsha L., Chang, Dolly, Chang, Robert T.“…Referable glaucoma included true glaucoma, pre-perimetric glaucoma, and high-risk suspects, based on qualitative fundus photographs, visual fields, OCT reports, and clinical examinations, including intraocular pressure (IOP) and treatment history as the binary (two class) ground truth. The curated real-world dataset did not include eyes with retinal disease or nonglaucomatous optic neuropathies. …”
Publicado 2020
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27432Publicado 2017“…The effective rate of rFⅦa was 25.0% (2/5) in 5 patients with cerebral hemorrhage, 66.7% (6/9) in 9 patients with hematuria and 41.7% in 12 patients with gastrointestinal hemorrhage. The curative effect for 3 patients with joints and muscle bleeding and 5 patients with skin, nasal, pharyngeal and gum bleeding was excellent. …”
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27433por Sorop, Andrei, Iacob, Razvan, Iacob, Speranta, Constantinescu, Diana, Chitoiu, Leona, Fertig, Tudor Emanuel, Dinischiotu, Anca, Chivu-Economescu, Mihaela, Bacalbasa, Nicolae, Savu, Lorand, Gheorghe, Liliana, Dima, Simona, Popescu, Irinel“…METHODS: The study group included 106 subjects: 48 patients diagnosed with HCC during screening, who underwent a potentially curative treatment (surgical resection or liver transplantation), 38 patients with liver cirrhosis (LC) on the waiting list for liver transplantation, and 20 healthy volunteers. …”
Publicado 2020
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27434Correlation of PD-L1 and SOCS3 Co-expression with the Prognosis of Hepatocellular Carcinoma Patientspor Chen, Liuxi, Huang, Xingxing, Zhang, Wenzheng, Liu, Ying, Chen, Bi, Xiang, Yu, Zhang, Ruonan, Zhang, Mingming, Feng, Jiao, Liu, Shuiping, Duan, Ting, Chen, Xiaying, Wang, Wengang, Pan, Ting, Yan, Lili, Jin, Ting, Li, Guohua, Li, Yongqiang, Xie, Tian, Sui, Xinbing“…Methods: We assessed the expression of PD-L1, CD276, SOCS3, CD4 and CD8 by immunohistochemistry in tumor tissue from 74 HCC patients who underwent curative hepatectomy. Results: High expression of PD-L1 was significantly associated with high Edmondson grade (p<0.01) and elevated enzyme (p=0.037); high expression of CD276 was significantly correlated with high Edmondson grade (p=0.021); high expression of SOCS3 was significantly associated with age (p=0.026) and tumor size (p=0.041), while PD-L1 showed no significant correlation. …”
Publicado 2020
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27435“…A total of 304 participants with CRC who had experienced curative surgery were included. Logistic regression analysis was performed to analyse the relationship between blood lipid levels and CRC severity. …”
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27436por Gambardella, Claudio, Clarizia, Guglielmo, Patrone, Renato, Offi, Chiara, Mauriello, Claudio, Romano, Roberto, Filardo, Marco, Conzo, Alessandra, Sanguinetti, Alessandro, Polistena, Andrea, Avenia, Nicola, Conzo, Giovanni“…Axillary lymph nodes dissection represents the treatment of choice in locally advanced breast cancer for prognostic and curative purposes. Seroma formation, an abnormal collection of fluid in the dead space of the axilla, is described in Literature with a wide range of incidence (3–85%). …”
Publicado 2019
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27437por Tan, Aihua, Wang, Miyuan, Liu, Jia, Huang, Kailin, Dai, Disha, Li, Lei, Shi, Heyuan, Wang, Ping“…Albeit a spike in related literatures, the curative effect and safety of the treatment are still in lack of evidence. …”
Publicado 2020
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27438por Seyedin, Steven N., Gannon, Margaret K., Plichta, Kristin A., Abushahin, Laith, Berg, Daniel J., Arshava, Evgeny V., Parekh, Kalpaj R., Keech, John C., Caster, Joseph M., Welsh, James W., Allen, Bryan G.“…Methods: This single-institution retrospective study assessed outcomes in patients who received SBRT for locoregional failure of esophageal cancer after initial curative-intent treatment. Only patients who had received neoadjuvant chemoradiation (≥41.4 Gy) for esophageal cancer were selected. …”
Publicado 2020
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27439por Liu, DM, Hadjivassiliou, A, Valenti, D, Ho, SG, Klass, D, Chung, JB, Kim, PT, Boucher, LM“…Evolving from percutaneous ethanol injection (PEI), thermal ablation utilizing radiofrequency ablation (RFA) and microwave ablation (MWA) have become the standard approach in the treatment of isolated lesions that fit within the size criteria for curative intent therapy (typically 3-4cm). With the evolution of more intense thermal ablation, such as MWA, the dramatic increase in both the size of ablation zone and intensity of heat generation have extended the limits of this technique. …”
Publicado 2020
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27440“…The measurement of B7-H1 or IL-10 in sera following surgery may provide an additional tool for assessing the curative effects of surgery in CRC patients.…”
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