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27501por Jethwa, Krishan R., Day, Courtney N., Sandhyavenu, Harigopal, Gonuguntla, Karthik, Harmsen, William S., Breen, William G., Routman, David M., Garda, Allison E., Hubbard, Joleen M., Halfdanarson, Thorvardur R., Neben-Wittich, Michelle A., Merrell, Kenneth W., Hallemeier, Christopher L., Haddock, Michael G.“…MATERIALS AND METHODS: This was a retrospective review of patients with ASCC who received curative-intent IMRT and concurrent chemotherapy (98%) between 2003 and 2019. …”
Publicado 2021
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27502por Yang, Changhong, Chen, Jialei, Yu, Zhe, Luo, Jing, Li, Xuemei, Zhou, Baoyong, Jiang, Ning“…Surgical resection for GBC is the only effective treatment, but most patients miss the opportunity for curative surgery because of a lack of timely diagnosis. …”
Publicado 2021
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27503por Janse, Ingmar, Beeloo, Rick, Swart, Arno, Visser, Michael, Schouls, Leo, van Duijkeren, Engeline, van Passel, Mark W.J.“…Based on publicly available genome sequences from PATRIC and manually curated CEG sequences from the beta lactam database, we found 7,964 bacterial genomes, belonging to at least 70 distinct species, that carry in total 9,892 CEGs, amongst which bla(NDM), bla(OXA), bla(VIM), bla(IMP) and bla(KPC). …”
Publicado 2021
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27504por Loosen, Sven H., Castoldi, Mirco, Jördens, Markus S., Roy, Sanchary, Vucur, Mihael, Kandler, Jennis, Hammerich, Linda, Mohr, Raphael, Tacke, Frank, Ulmer, Tom F., Neumann, Ulf P., Luedde, Tom, Roderburg, Christoph“…BACKGROUND: Early detection of hepatocellular carcinoma (HCC), the most common primary liver malignancy, is crucial to offer patients a potentially curative treatment strategy such as surgical resection or liver transplantation (LT). …”
Publicado 2021
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27505por Kim, Tae Jun, Lee, Yeong Chan, Min, Yang Won, Lee, Hyuk, Min, Byung-Hoon, Lee, Jun Haeng, Won, Hong-Hee, Song, Kyoung Doo, Jeong, Woo Kyoung, Kim, Jae J.“…We found a significant relationship between the frequency of CT scans and the subsequent incidence of secondary primary malignancies in patients who have undergone curative resection for early gastric cancer (EGC). …”
Publicado 2021
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27506por Shackleton, Erin G., Ali, Haleema Yoosuf, Khan, Masood, Pockley, Graham A., McArdle, Stephanie E.“…ABSTRACT: Prostate cancer (PCa) is the second-most common cancer in men worldwide and treatment options for patients with advanced or aggressive prostate cancer or recurrent disease continue to be of limited success and are rarely curative. Despite immune checkpoint blockade (ICB) efficacy in some melanoma, lung, kidney and breast cancers, immunotherapy efforts have been remarkably unsuccessful in PCa. …”
Publicado 2021
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27507por Yongfeng, Piao, Chuner, Jiang, Lei, Wang, Fengqin, Yan, Zhimin, Ye, Zhenfu, Fu, Haitao, Jiang, Yangming, Jiang, Fangzheng, Wang“…The predictive model based on MRI-enhanced sequence imaging could distinguish the sensitivity and resistance to NAC and provide new biomarkers for the early prediction of the curative effect in NPC patients.…”
Publicado 2021
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27508por Watanabe, J., Sasaki, S., Kusumoto, T., Sakamoto, Y., Yoshida, K., Tomita, N., Maeda, A., Teshima, J., Yokota, M., Tanaka, C., Yamauchi, J., Uetake, H., Itabashi, M., Takahashi, K., Baba, H., Kotake, K., Boku, N., Aiba, K., Morita, S., Takenaka, N., Sugihara, K.“…PATIENTS AND METHODS: Patients who underwent curative resection for pathologically confirmed high-risk stage III colon cancer were randomly assigned to receive either UFT/LV (300 mg/m(2) of UFT and 75 mg/day of LV on days 1-28, every 35 days, five cycles) or SOX (100 mg/m(2) of oxaliplatin on day 1 and 80 mg/m(2)/day of S-1 on days 1-14, every 21 days, eight cycles). …”
Publicado 2021
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27509por Pascal Saint-Firmin, Patrick, Diakite, Birama, Ward, Kevin, Benard, Mitto, Stratton, Sara, Ortiz, Christine, Dutta, Arin, Traore, Seydou“…RESULTS: Thirteen financing sources contributed to CHW program expenditures, 88% of which were from international donors, for a package of 23 curative, preventive, and promotive interventions. …”
Publicado 2021
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27510“…To date, there is no proven curative treatment for this virus; as a result, prevention remains to be the best strategy to combat coronavirus infection (COVID-19). …”
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27511por Yadav, Sushma, Asthana, Anupama, Singh, Ajaya Kumar, Chakraborty, Rupa, Sree Vidya, S., Singh, Ambrish, Carabineiro, Sónia A. C.“…In spite of the growing demand for new antibiotics, in the recent years, the occurrence of fluoroquinolone antibiotics (as a curative agent for urinary tract disorders and respiratory problems) in wastewater have drawn immense attention. …”
Publicado 2021
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27512por Kuroda, Hidekatsu, Nagasawa, Tomoaki, Fujiwara, Yudai, Sato, Hiroki, Abe, Tamami, Kooka, Yohei, Endo, Kei, Oikawa, Takayoshi, Sawara, Kei, Takikawa, Yasuhiro“…Microwave ablation led to a high rate of curative ablation (94.7%) and a low rate of local recurrence (3.3%), with an overall survival rate of 99.3% at 1 year (recurrence-free survival: 81.1%) and 88.4% at 2 years (recurrence-free survival: 60.5%). …”
Publicado 2021
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27513por Lindemann, Kristina, Smogeli, Elisabeth, Småstuen, Milada Cvancarova, Bruheim, Kjersti, Trovik, Jone, Nordberg, Terje, Kristensen, Gunnar B., Werner, Henrica M. J., Nakken, Esten“…ABSTRACT: (1) Background: This study evaluated the clinical outcome after salvage radiotherapy for first pelvic relapse after endometrial cancer (EC). (2) Methods: This multicenter retrospective study included EC patients with first central pelvic relapse without lymph node involvement treated with curative intent. Progression-free (PFS) and overall survival (OS) were calculated with the Kaplan–Meier method and possible predictive factors for risk of relapse and mortality were identified using the Cox model. (3) Results: We included 139 patients with median EQD2 (Equivalent Dose in 2 Gy fractions) to the clinical target volume of 70.0 Gy. …”
Publicado 2021
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27514por Marcus, Damiënne, Lieverse, Relinde I. Y., Klein, Carmen, Abdollahi, Amir, Lambin, Philippe, Dubois, Ludwig J., Yaromina, Ala“…Despite the clinical success of ICI and RT combination, e.g., prolonging overall survival in locally advanced lung cancer, curative outcomes are still not achieved for most cancer entities studied. …”
Publicado 2021
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27515por Dromain, Clarisse, Loaiza‐Bonilla, Arturo, Mirakhur, Beloo, Beveridge, Thomas J.R., Fojo, Antonio Tito“…IMPLICATIONS FOR PRACTICE: The only curative treatment for neuroendocrine tumors (NETs) is surgical resection; however, because of frequent late diagnosis, this is often impossible. …”
Publicado 2021
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27516por Stefano, Mauro, Prosperi, Enrico, Fugazzola, Paola, Benini, Beatrice, Bisulli, Marcello, Coccolini, Federico, Mastronardi, Costantino, Palladino, Alessandro, Tomasoni, Matteo, Agnoletti, Vanni, Giampalma, Emanuela, Ansaloni, Luca“…Introduction: Cholangiocarcinoma (CCA) is the second most common primary tumor of the liver, and the recurrence after hepatic resection (HR), the only curative therapy, is linked with a worse prognosis. …”
Publicado 2021
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27517por Chen, Wen-Ting, Tang, Rui-Mei, Huang, Ying, Pan, Yan-Ping, Wang, Shu-Wen, Wang, Gu-Yun“…At this stage, a large number of randomized controlled studies have reported that Chinese herbal medicine has achieved good curative effect in the treatment of ITP. However, due to the variety of Chinese herbal medicine, there has been no evidence of the effectiveness and safety of Chinese herbal medicine in the treatment of ITP. …”
Publicado 2021
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27518por Zhou, Minran, Yin, Xiaolin, Zheng, Lixin, Fu, Yue, Wang, Yue, Cui, Zelong, Gao, Zhenxing, Wang, Xiaoming, Huang, Tao, Jia, Jihui, Chen, Chunyan“…Once it progresses into the phase of blast crisis (CML-BP), the curative effect is poor, and the fatality rate is extremely high. …”
Publicado 2021
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27519por Ossami Saidy, Ramin Raul, Postel, Maximilian Paul, Pflüger, Michael Johannes, Schoening, Wenzel, Öllinger, Robert, Gül-Klein, Safak, Schmelzle, Moritz, Tacke, Frank, Pratschke, Johann, Eurich, Dennis“…SIMPLE SUMMARY: Liver transplantation is a curative treatment option for a subset of patients with hepatocellular carcinoma (HCC). …”
Publicado 2021
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27520por Modi, Chirag, Dragun, Anthony E., Henson, Clarissa F., Jain, Sheena, Ahlawat, Stuti, Eastwick, Gary, Kubicek, Gregory J., Mezera, Megan, Mulvihill, David J., Perri, Jennifer, Juneja, Badal, Khullar, Karishma, Ennis, Ronald D., Haffty, Bruce G.“…All five patients were treated for different primary tumor sites, the large majority had advanced disease (80%), and all were treated for curative intent. The majority of positive patients were being treated with either sequential or concurrent immunosuppressive systemic therapy (80%). …”
Publicado 2021
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