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27541por Devillier, Raynier, Calmels, Boris, Guia, Sophie, Taha, Mohammed, Fauriat, Cyril, Mfarrej, Bechara, Venton, Geoffroy, Vivier, Eric, Olive, Daniel, Chabannon, Christian, Blaise, Didier, Ugolini, Sophie“…SIMPLE SUMMARY: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative option for high-risk hematologic malignancies. …”
Publicado 2021
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27542por Takahashi, Hidekazu, Okayama, Naoko, Yamaguchi, Natsu, Nomura, Moe, Miyahara, Yuta, Mahbub, MH, Hase, Ryosuke, Morishima, Yasuo, Suehiro, Yutaka, Yamasaki, Takahiro, Tamada, Koji, Takahashi, Satoshi, Tojo, Arinobu, Tanabe, Tsuyoshi“…SIMPLE SUMMARY: Hematopoietic stem-cell transplantation (HSCT) is a curative therapy for blood disorders. Unrelated bone marrow transplantation (uBMT) is a type of allogeneic HSCT that uses the bone marrow of an unrelated donor. …”
Publicado 2021
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27543por Park, Joo Kyung, Kim, Hyemin, Son, Dae-Soon, Kim, Nayoung K. D., Sung, Young Kyung, Cho, Minseob, Lee, Chung, Noh, Dong Hyo, Lee, Se-Hoon, Lee, Kyu Taek, Lee, Jong Kyun, Jang, Kee-Taek, Park, Woong-Yang, Lee, Kwang Hyuck“…SIMPLE SUMMARY: Around 10–20% of patients with pancreatic adenocarcinoma (PDAC) have a curative surgery, but most of them perform endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) for the pathologic confirmation. …”
Publicado 2021
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27544por Bottke, Dirk, Miksch, Jonathan, Thamm, Reinhard, Krohn, Thomas, Bartkowiak, Detlef, Beer, Meinrad, Bolenz, Christian, Beer, Ambros J., Prasad, Vikas, Wiegel, Thomas“…BACKGROUND AND PURPOSE: Salvage radiotherapy (SRT) is the main potentially curative treatment option for prostate cancer patients with post-prostatectomy PSA progression. …”
Publicado 2021
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27545por Antognelli, Cinzia, Mandarano, Martina, Prosperi, Enrico, Sidoni, Angelo, Talesa, Vincenzo Nicola“…ABSTRACT: Metastatic prostate cancer (mPCa) is a disease for which to date there is not curative therapy. Even the recent and attractive immunotherapeutic approaches targeting PD-L1, an immune checkpoint protein which helps cancer cells to escape from immunosurveillance, have proved ineffective. …”
Publicado 2021
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27546por Benech, Nicolas, O'Brien, Jean Marc, Barret, Maximilien, Jacques, Jéremie, Rahmi, Gabriel, Perrod, Guillaume, Hervieu, Valérie, Jaouen, Alexandre, Charissoux, Aurélie, Guillaud, Olivier, Legros, Romain, Walter, Thomas, Saurin, Jean‐Christophe, Rivory, Jérôme, Prat, Fréderic, Lépilliez, Vincent, Ponchon, Thierry, Pioche, Mathieu“…BACKGROUND: Superficial oesophageal adenocarcinoma can be resected endoscopically, but data to define a curative endoscopic resection are scarce. OBJECTIVE: Our study aimed to assess the risk of lymph node metastasis depending on the depth of invasion and histological features of oesophageal adenocarcinoma. …”
Publicado 2021
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27547por She, Wong Hoi, Chan, Albert C. Y., Ma, Ka Wing, Dai, Wing Chiu, Chok, Kenneth S. H., Cheung, Tan To, Lo, Chung Mau“…METHODS: Patients who had primary, curative resection for HCC between 1989 and 2017 were reviewed. …”
Publicado 2021
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27548“…Finally, TMEM131 and DARS genes were identified in this study whose roles have never been interrogated in any kind of cancer, neither as a biomarker nor curative target. All the mentioned mechanisms must be further validated by experimental wet-lab techniques.…”
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27549por Shim, Won Sang, Yim, Kwangil, Kim, Tae-Jung, Sung, Yeoun Eun, Lee, Gyeongyun, Hong, Ji Hyung, Chun, Sang Hoon, Kim, Seoree, An, Ho Jung, Na, Sae Jung, Kim, Jae Jun, Moon, Mi Hyoung, Moon, Seok Whan, Park, Sungsoo, Hong, Soon Auck, Ko, Yoon Ho“…Despite the limitations associated with a relatively small number of patients, the DeepRePath model based on CNNs with transfer learning could predict recurrence after the curative resection of early-stage LUAD using multi-scale pathology images.…”
Publicado 2021
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27550por Purkayastha, Joydeep, Singh, Pritesh Rajeev, Talukdar, Abhijit, Das, Gaurav, Yadav, Jitin, Bannoth, Srinivas“…All patients underwent surgery with curative intent. All patients underwent open surgery of which 66.7% underwent colectomy, 14.8% underwent anterior resection, 11.1% underwent Miles procedure, and 7.4% underwent pelvic exenteration. …”
Publicado 2021
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27551por Parisek, Mira, Loss, Julika, Holler, Ernst, Barata, Anna, Weber, Daniela, Edinger, Matthias, Wolff, Daniel, Schoemans, Helene, Herrmann, Anne“…Background: Allogeneic hematopoietic stem cell transplantation (alloHSCT) is the only curative treatment modality for many patients affected by hematologic malignancies. …”
Publicado 2021
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27552“…Six MADS-box genes (PavDAMs), orthologs to peach and Japanese apricot DAMs, were identified as candidate genes for bloom time regulation. The complete curated genomic structure annotation of these genes is reported. …”
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27553por de la Fouchardière, Christelle, Adham, Mustapha, Marion-Audibert, Anne-Marie, Duclos, Antoine, Darcha, Claude, Berthelet, Olivier, Hervieu, Valérie, Artru, Pascal, Labrosse, Hélène, Fayet, Yohan, Ferroud-Plattet, Bruno, Aublet-Cuvellier, Bruno, Chambon, Georges, Baconnier, Mathieu, Rebischung, Christine, Farsi, Fadila, Ray-Coquard, Isabelle, Mastier, Charles, Ternamian, Pierre-Jean, Williet, Nicolas, Buc, Emmanuel, Walter, Thomas, Herr, Andrée-Laure“…Within the follow-up period, 353 (18.9%) were operated with a curative intent, 743 (39.7%) underwent chemo- and/or radiotherapy, and 776 (41.4%) did not receive any of these treatments. …”
Publicado 2021
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27554por Berger, Amnon A., Liu, Yao, Jin, Kevin, Kaneb, Alicia, Welschmeyer, Alexandra, Cornett, Elyse M., Kaye, Alan David, Imani, Farnad, Khademi, Seyed-Hosein, Varrassi, Giustino, Viswanath, Omar, Urits, Ivan“…Clinical trials studying acupuncture in chronic pain conditions have been promising, and recent evidence supports the use of abdominal pain in chronic abdominal pain conditions as well. Though not curative, acupuncture is a complementary approach that helps reduce symptoms and improved quality of life. …”
Publicado 2021
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27555por Liu, Xianping, Sun, Kunkun, Yang, Fan, Sui, Xizhao, Jiang, Guanchao, Wang, Jun, Li, Xiao“…OBJECTIVES: To accurately describe the pattern, timing and predictors of disease recurrence after curative resection for different types of early‐stage lung adenocarcinoma (LUAD). …”
Publicado 2021
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27556por Fecho, Karamarie, Bizon, Chris, Miller, Frederick, Schurman, Shepherd, Schmitt, Charles, Xue, William, Morton, Kenneth, Wang, Patrick, Tropsha, Alexander“…Users can also posit questions through direct Cypher query of the underlying knowledge graph, which currently contains roughly 6 million nodes or biomedical entities and 140 million edges or predicates describing the relationship between nodes, drawn from over 30 curated data sources. OBJECTIVE: We aimed to apply ROBOKOP to survey data on workplace exposures and immune-mediated diseases from the Environmental Polymorphisms Registry (EPR) within the National Institute of Environmental Health Sciences. …”
Publicado 2021
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27557“…After 3 months of treatment, the curative effect was investigated. Serum tumor markers, peripheral blood Th1/Th2 cells, and side effects and recurrence rate were compared between the two groups. …”
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27558por Tan, Zhen, Lei, Yubin, Zhang, Bo, Shi, Si, Liu, Jiang, Yu, Xianjun, Xu, Jin, Liang, Chen“…Immunotherapy and targeted therapy confirmed an existing certain curative effect in treating PDAC. The aim of this study was to develop an immune-related molecular marker to enhance the ability to predict Stages III and IV PDAC patients. …”
Publicado 2021
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27559por Moraru, Dan Cristian, Scripcariu, Dragoş Viorel, Ferariu, Dan, Scripcariu, Viorel, Filip, Bogdan“…In 5.5 years of evolution, out of 620 patients with rectal cancer treated by curative surgery, 176 patients with lower ampullary rectal cancer treated by abdominoperineal resection (APR) with the closure of the defect by direct suture of the perineal floor were selected. …”
Publicado 2020
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27560por Barnhart, Dale A, Kamali, Innocent, Nyirahabihirwe, Francoise, Mugabo, Carol, Gakuru, Jean de la Paix, Uwase, Mariam, Nizeyumuremyi, Esdras, Musafiri, Tumusime, Gatete, Jean de Dieu, Makuza, Jean Damascene, Kateera, Fredrick, Hedt-Gauthier, Bethany, Ndahimana, Jean d’Amour“…BACKGROUND: Curative direct-acting antiviral treatment (DAA) has made it plausible to implement hepatitis C elimination interventions. …”
Publicado 2021
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