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  1. 27561
    “…This study presents the meticulous manual curation of more than 200 articles that specifically interrogate the biomarker potential of miRNAs in whole blood, serum, or plasma. …”
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    PlasmiR: A Manual Collection of Circulating microRNAs of Prognostic and Diagnostic Value
  2. 27562
    “…METHODS: Clinical data of 98 patients with confirmed COVID-19 diagnosis were acquired from electronic medical records and curated. The data were analyzed based on the stage of the admission, deterioration, and convalescence, which included age, sex, severity, disease stages, biochemical indicators, immune cells, inflammatory cytokines, and immunoglobulins. …”
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    Analysis of the dynamic relationship between immune profiles and the clinical features of patients with COVID-19
  3. 27563
    “…Treatment with chemoradiation therapy harbors a risk of local residual disease, which can be curatively treated with salvage surgery, but the risk of complications following surgical procedures in radiated tissue is not negligible. …”
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    Salvage surgery for patients with residual disease after chemoradiation therapy for locally advanced cervical cancer: A systematic review on indication, complications, and survival
  4. 27564
    “…METHODS: The clinical and histological records of 389 colorectal cancer (CRC) patients who underwent curative surgery were reviewed. RESULTS: For the ENE system, 244 patients were in the ENE1 group and 145 in the ENE2 system. …”
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    Prognostic implications of ENE and LODDS in relation to lymph node-positive colorectal cancer location
  5. 27565
    “…BACKGROUND: Salvage radiotherapy (sRT) is the main potentially curative treatment after biochemical failure/locoregional relapse post-radical prostatectomy (RP). …”
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    Pathological stage, surgical margin and lymphovascular invasion as prognostic factors after salvage radiotherapy for post-prostatectomy relapsed prostate cancer — outcomes and optimization strategies
  6. 27566
    “…In transcriptomic datasets curated from public repositories, we observed a consistent upregulation (3.26–5.29 fold) of ERLIN1—a gene coding for an ER membrane prohibitin and a regulator of inositol 1, 4, 5-trisphosphate receptors and sterol regulatory element-binding proteins—under septic conditions in healthy neutrophils, monocytes, and whole blood. …”
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    Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis
  7. 27567
    “…Surgical excision of the primary tumor is the curative intent treatment; however, recurrence occurs in approximately 20% of patients. …”
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    Increased CD3(+), CD8(+), or FoxP3(+) T Lymphocyte Infiltrations Are Associated with the Pathogenesis of Colorectal Cancer but Not with the Overall Survival of Patients
  8. 27568
    “…Furthermore, based on the prediction of network pharmacology study, a mouse model of PCOS was established to evaluate the curative role and underlying mechanisms of C. chinensis. …”
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    Network Pharmacology-Based Strategy for Predicting Active Ingredients and Potential Targets of Coptis chinensis Franchin Polycystic Ovary Syndrome
  9. 27569
    “…In the logistic model, as adjusted covariates, sex, age, treatment (palliative vs. curative), tumor type, and the lowest level of neutrophils were used. …”
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    A Multicenter Analysis of the Outcome of Cancer Patients with Neutropenia and COVID-19 Optionally Treated with Granulocyte-Colony Stimulating Factor (G-CSF): A Comparative Analysis
  10. 27570
    “…A subset of the data was formatted, curated, standardized and harmonized. Descriptive analysis was carried out, and results reported. …”
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    Preliminary Results from the FOGSI's National Registry on Pregnancy with COVID-19
  11. 27571
    “…In this study, we compiled a curated database of 2,431 Nucleocytoviricota genomes and used it to examine the gene expression of these viruses in a 2.5-day metatranscriptomic time-series from surface waters of the California Current. …”
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    High Transcriptional Activity and Diverse Functional Repertoires of Hundreds of Giant Viruses in a Coastal Marine System
  12. 27572
    por Zhao, Juan, Zhou, Li, Pan, Yan, Chen, Lan
    Publicado 2021
    “…BACKGROUND: A meta-analysis was conducted to evaluate the curative effect of radical cystectomy in the treatment of muscular invasive bladder cancer (MIBC). …”
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    A systematic review and meta-analysis of radical cystectomy in the treatment of muscular invasive bladder cancer (MIBC)
  13. 27573
    por Lu, Ying, Wu, Ning, Ma, Bin, Qin, Feng
    Publicado 2021
    “…CONCLUSION: Root canal therapy and full crown restoration have a definite curative effect in patients with cracked teeth and chronic pulpitis, which can improve the inflammatory response, restore chewing function, maintain periodontal health, improve the quality of life, and do not increase the incidence of complications, so it has good application value.…”
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    Effect of Root Canal Therapy Combined with Full Crown Restoration on the Level of Inflammatory Factors and Chewing Function in Patients with Cracked Teeth and Chronic Pulpitis
  14. 27574
    “…IMPORTANCE A major by-product of all adeno-associated virus (AAV) vector production systems are “empty” capsids, void of the desired therapeutic gene, and thus do not provide any curative benefit for the treatment of the targeted disease. …”
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    Improved Genome Packaging Efficiency of Adeno-associated Virus Vectors Using Rep Hybrids
  15. 27575
    “…BACKGROUND: Alzheimer’s disease (AD) is the most common type of dementia. However, no curative therapy has been found effective to slow down the process of AD. …”
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    Stress Granules Modulate SYK to Cause Tau-Associated Neurocognitive Deterioration in 5XFAD Mouse After Anesthesia and Surgery
  16. 27576
    “…The detailed information about the curated gene list, cross-species orthologs, PPIN, and pathways was assembled in an interactive data visualization portal using RStudio’s Shiny framework (https://agingnetwork.shinyapps.io/frontiers/).…”
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    Cross-Species and Human Inter-Tissue Network Analysis of Genes Implicated in Longevity and Aging Reveal Strong Support for Nutrient Sensing
  17. 27577
    “…Unfortunately, a quarter of all patients are diagnosed at late stages, when curative surgery is not possible, rendering systemic therapy and/or best supportive care as the only options. …”
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    Immune-Checkpoint Inhibitors for Metastatic Colorectal Cancer: A Systematic Review of Clinical Outcomes
  18. 27578
    “…Haploidentical stem cell transplantation (haploSCT) has greatly improved access to curative treatment for myeloid malignancies in patients without suitable matched sibling/unrelated donors. …”
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    Safety and Efficacy of Haploidentical Peripheral Blood Stem Cell Transplantation for Myeloid Malignancies Using Post-transplantation Cyclophosphamide and Anti-thymocyte Globulin as Graft-versus-Host Disease Prophylaxis
  19. 27579
    “…INTRODUCTION: Gene therapy have recently attracted much attention as a curative therapeutic option for inherited single gene disorders such as hemophilia. …”
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    Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model
  20. 27580
    “…CONCLUSION: The extract of curry leaves at a dose of 300 mg/kg BW with preventive and curative effects can potentially be used as an anti-tumor agent, which effectively induces the apoptosis of tumor cells.…”
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    Effects of ethanol extract of curry leaves (Murraya koenigii) on HER2 and caspase-3 expression in rat model mammary carcinoma
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